Michael Otto
Michael Otto
Senior Investigator, NIAID
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Cited by
Cited by
Staphylococcus epidermidis — the 'accidental' pathogen
M Otto
Nature reviews microbiology 7 (8), 555-567, 2009
Community-associated meticillin-resistant Staphylococcus aureus
FR DeLeo, M Otto, BN Kreiswirth, HF Chambers
The Lancet 375 (9725), 1557-1568, 2010
Staphylococcal biofilms
M Otto
Bacterial biofilms, 207-228, 2008
Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA
R Wang, KR Braughton, D Kretschmer, THL Bach, SY Queck, M Li, ...
Nature medicine 13 (12), 1510-1514, 2007
Inactivation of the dlt Operon inStaphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides
A Peschel, M Otto, RW Jack, H Kalbacher, G Jung, F Gotz
Journal of Biological Chemistry 274 (13), 8405-8410, 1999
Staphylococcus epidermidis infections
C Vuong, M Otto
Microbes and infection 4 (4), 481-489, 2002
Staphylococcus aureus Resistance to Human Defensins and Evasion of Neutrophil Killing via the Novel Virulence Factor Mprf Is Based on Modification of Membrane Lipidsá…
A Peschel, RW Jack, M Otto, LV Collins, P Staubitz, G Nicholson, ...
The Journal of experimental medicine 193 (9), 1067-1076, 2001
Polysaccharide intercellular adhesin (PIA) protects Staphylococcus epidermidis against major components of the human innate immune system
C Vuong, JM Voyich, ER Fischer, KR Braughton, AR Whitney, FR DeLeo, ...
Cellular microbiology 6 (3), 269-275, 2004
A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion, and virulence
C Vuong, S Kocianova, JM Voyich, Y Yao, ER Fischer, FR DeLeo, M Otto
Journal of Biological Chemistry 279 (52), 54881-54886, 2004
Staphylococcus aureus toxins
M Otto
Current opinion in microbiology 17, 32-37, 2014
Is Panton‐Valentine Leukocidin the Major Virulence Determinant in Community‐Associated Methicillin‐Resistant Staphylococcus aureus Disease?
JM Voyich, M Otto, B Mathema, KR Braughton, AR Whitney, D Welty, ...
The Journal of infectious diseases 194 (12), 1761-1770, 2006
How Staphylococcus aureus biofilms develop their characteristic structure
S Periasamy, HS Joo, AC Duong, THL Bach, VY Tan, SS Chatterjee, ...
Proceedings of the National Academy of Sciences 109 (4), 1281-1286, 2012
Staphylococcal infections: mechanisms of biofilm maturation and detachment as critical determinants of pathogenicity
M Otto
Annual review of medicine 64, 175-188, 2013
Pathogenicity and virulence of Staphylococcus aureus
GYC Cheung, JS Bae, M Otto
Virulence 12 (1), 547-569, 2021
Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance
SW Dickey, GYC Cheung, M Otto
Nature Reviews Drug Discovery 16 (7), 457-471, 2017
Impact of the agr Quorum-Sensing System on Adherence to Polystyrene in Staphylococcus aureus
C Vuong, HL Saenz, F G÷tz, M Otto
The Journal of infectious diseases 182 (6), 1688-1693, 2000
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus
SY Queck, M Jameson-Lee, AE Villaruz, THL Bach, BA Khan, ...
Molecular cell 32 (1), 150-158, 2008
Poring over pores: α-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia
J Bubeck Wardenburg, T Bae, M Otto, FR DeLeo, O Schneewind
Nature medicine 13 (12), 1405-1406, 2007
Basis of Virulence in Community-Associated Methicillin-Resistant Staphylococcus aureus
M Otto
Annual review of microbiology 64, 143-162, 2010
Staphylococcus δ-toxin induces allergic skin disease by activating mast cells
Y Nakamura, J Oscherwitz, KB Cease, SM Chan, R Mu˝oz-Planillo, ...
Nature 503 (7476), 397-401, 2013
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