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Andrew McGuire
Andrew McGuire
Assistant Professor, Vaccine and Infectious Disease Division
Verified email at fredhutch.org - Homepage
Title
Cited by
Cited by
Year
Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein
AC Walls, YJ Park, MA Tortorici, A Wall, AT McGuire, D Veesler
Cell 181 (2), 281-292. e6, 2020
70382020
Rational HIV immunogen design to target specific germline B cell receptors
J Jardine, JP Julien, S Menis, T Ota, O Kalyuzhniy, A McGuire, D Sok, ...
Science 340 (6133), 711-716, 2013
6472013
mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection
L Stamatatos, J Czartoski, YH Wan, LJ Homad, V Rubin, H Glantz, ...
Science 372 (6549), 1413-1418, 2021
3142021
Analysis of a SARS-CoV-2-infected individual reveals development of potent neutralizing antibodies with limited somatic mutation
E Seydoux, LJ Homad, AJ MacCamy, KR Parks, NK Hurlburt, ...
Immunity 53 (1), 98-105. e5, 2020
3032020
Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies
AT McGuire, S Hoot, AM Dreyer, A Lippy, A Stuart, KW Cohen, J Jardine, ...
Journal of Experimental Medicine 210 (4), 655-663, 2013
2982013
Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice
P Dosenovic, L von Boehmer, A Escolano, J Jardine, NT Freund, AD Gitlin, ...
Cell 161 (7), 1505-1515, 2015
2452015
Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs
S Hoot, AT McGuire, KW Cohen, RK Strong, L Hangartner, F Klein, ...
PLoS pathogens 9 (1), e1003106, 2013
1982013
Induction of HIV neutralizing antibody lineages in mice with diverse precursor repertoires
M Tian, C Cheng, X Chen, H Duan, HL Cheng, M Dao, Z Sheng, M Kimble, ...
Cell 166 (6), 1471-1484. e18, 2016
1562016
Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice
AT McGuire, MD Gray, P Dosenovic, AD Gitlin, NT Freund, J Petersen, ...
Nature communications 7 (1), 1-10, 2016
1472016
Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation
NK Hurlburt, E Seydoux, YH Wan, VV Edara, AB Stuart, J Feng, ...
Nature communications 11 (1), 1-7, 2020
1222020
Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies
AT McGuire, AM Dreyer, S Carbonetti, A Lippy, J Glenn, JF Scheid, ...
Science 346 (6215), 1380-1383, 2014
1172014
Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections
X Xiong, MA Tortorici, J Snijder, C Yoshioka, AC Walls, W Li, AT McGuire, ...
Journal of virology 92 (4), e01628-17, 2018
1152018
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
M Medina-Ramírez, F Garces, A Escolano, P Skog, SW de Taeye, ...
Journal of Experimental Medicine 214 (9), 2573-2590, 2017
1122017
Molecular signatures of hemagglutinin stem-directed heterosubtypic human neutralizing antibodies against influenza A viruses
Y Avnir, AS Tallarico, Q Zhu, AS Bennett, G Connelly, J Sheehan, J Sui, ...
PLoS pathogens 10 (5), e1004103, 2014
1062014
Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques
A Escolano, HB Gristick, ME Abernathy, J Merkenschlager, R Gautam, ...
Nature 570 (7762), 468-473, 2019
1002019
Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study
KM Hastie, H Li, D Bedinger, SL Schendel, SM Dennison, K Li, ...
Science 374 (6566), 472-478, 2021
822021
An antibody targeting the fusion machinery neutralizes dual-tropic infection and defines a site of vulnerability on Epstein-Barr virus
J Snijder, MS Ortego, C Weidle, AB Stuart, MD Gray, MJ McElrath, ...
Immunity 48 (4), 799-811. e9, 2018
782018
Germline‐targeting immunogens
L Stamatatos, M Pancera, AT McGuire
Immunological reviews 275 (1), 203-216, 2017
782017
Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D
AT McGuire, JA Glenn, A Lippy, L Stamatatos
Journal of virology 88 (5), 2645-2657, 2014
772014
A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses
A Tauzin, M Nayrac, M Benlarbi, SY Gong, R Gasser, ...
Cell host & microbe 29 (7), 1137-1150. e6, 2021
722021
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