| ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43 R Stoica, KJ De Vos, S Paillusson, S Mueller, RM Sancho, KF Lau, ... Nature communications 5 (1), 3996, 2014 | 585 | 2014 |
| VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis KJ De Vos, GM Morotz, R Stoica, EL Tudor, KF Lau, S Ackerley, A Warley, ... Human molecular genetics 21 (6), 1299-1311, 2012 | 501 | 2012 |
| Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content KJ De Vos, AL Chapman, ME Tennant, C Manser, EL Tudor, KF Lau, ... Human molecular genetics 16 (22), 2720-2728, 2007 | 484 | 2007 |
| Expression analysis of glycogen synthase kinase‐3 in human tissues KF Lau, CCJ Miller, BH Anderton, PC Shaw The Journal of peptide research 54 (1), 85-91, 1999 | 160 | 1999 |
| Phosphorylation of thr668 in the cytoplasmic domain of the Alzheimer's disease amyloid precursor protein by stress‐activated protein kinase 1b (Jun N‐terminal … CL Standen, J Brownlees, AJ Grierson, S Kesavapany, KF Lau, ... Journal of neurochemistry 76 (1), 316-320, 2001 | 158 | 2001 |
| CAG expansion induces nucleolar stress in polyglutamine diseases H Tsoi, TCK Lau, SY Tsang, KF Lau, HYE Chan Proceedings of the National Academy of Sciences 109 (33), 13428-13433, 2012 | 150 | 2012 |
| BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper B Angeletti, KJ Waldron, KB Freeman, H Bawagan, I Hussain, CCJ Miller, ... Journal of Biological Chemistry 280 (18), 17930-17937, 2005 | 147 | 2005 |
| X11α and X11β interact with presenilin-1 via their PDZ domains KF Lau, DM McLoughlin, C Standen, CCJ Miller Molecular and Cellular Neuroscience 16 (5), 557-565, 2000 | 129 | 2000 |
| The X11 proteins, Aβ production and Alzheimer's disease CCJ Miller, DM McLoughlin, KF Lau, ME Tennant, B Rogelj Trends in neurosciences 29 (5), 280-285, 2006 | 123 | 2006 |
| p35/cdk5 binds and phosphorylates β‐catenin and regulates β‐catenin/presenilin‐1 interaction S Kesavapany, KF Lau, DM McLoughlin, J Brownlees, S Ackerley, ... European Journal of Neuroscience 13 (2), 241-247, 2001 | 122 | 2001 |
| The neuronal adaptor protein X11α reduces Aβ levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice JH Lee, KF Lau, MS Perkinton, CL Standen, SJA Shemilt, L Mercken, ... Journal of Biological Chemistry 278 (47), 47025-47029, 2003 | 109 | 2003 |
| Molecular cloning and characterization of the human glycogen synthase kinase-3β promoter KF Lau, CCJ Miller, BH Anderton, PC Shaw Genomics 60 (2), 121-128, 1999 | 106 | 1999 |
| The c-Abl tyrosine kinase phosphorylates the Fe65 adaptor protein to stimulate Fe65/amyloid precursor protein nuclear signaling MS Perkinton, CL Standen, KF Lau, S Kesavapany, HL Byers, M Ward, ... Journal of Biological Chemistry 279 (21), 22084-22091, 2004 | 99 | 2004 |
| Isolation and chromosomal mapping of human glycogen synthase kinase-3 α and-3β encoding genes PC Shaw, AF Davies, KF Lau, M Garcia-Barcelo, MMY Waye, ... Genome 41 (5), 720-727, 1998 | 96 | 1998 |
| The lysosomal protein cathepsin L is a progranulin protease CW Lee, JN Stankowski, J Chew, CN Cook, YW Lam, S Almeida, ... Molecular neurodegeneration 12, 1-9, 2017 | 92 | 2017 |
| Cyclin-dependent kinase-5/p35 phosphorylates Presenilin 1 to regulate carboxy-terminal fragment stability KF Lau, DR Howlett, S Kesavapany, CL Standen, C Dingwall, ... Molecular and Cellular Neuroscience 20 (1), 13-20, 2002 | 92 | 2002 |
| Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology EL Tudor, CM Galtrey, MS Perkinton, KF Lau, KJ De Vos, JC Mitchell, ... Neuroscience 167 (3), 774-785, 2010 | 91 | 2010 |
| A novel missense mutation in CCDC88C activates the JNK pathway and causes a dominant form of spinocerebellar ataxia H Tsoi, CS Allen, ZS Chen, NKN Ng, AYY Chan, LYP Yuen, JM Abrigo, ... Journal of Medical Genetics 51 (9), 590-595, 2014 | 87 | 2014 |
| Glycogen synthase kinase-3β-mediated tau phosphorylation in cultured cell lines CWC Lee, KF Lau, CCJ Miller, PC Shaw Neuroreport 14 (2), 257-260, 2003 | 86 | 2003 |
| Cryptotanshinone, an acetylcholinesterase inhibitor from Salvia miltiorrhiza, ameliorates scopolamine-induced amnesia in Morris water maze task KKK Wong, MTW Ho, HQ Lin, KF Lau, JA Rudd, RCK Chung, KP Fung, ... Planta medica 76 (03), 228-234, 2010 | 85 | 2010 |
