John E Bowen
John E Bowen
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Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ...
Cell 182 (5), 1295-1310. e20, 2020
Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
L Piccoli, YJ Park, MA Tortorici, N Czudnochowski, AC Walls, ...
Cell 183 (4), 1024-1042. e21, 2020
Sensitivity of SARS-CoV-2 B. 1.1. 7 to mRNA vaccine-elicited antibodies
DA Collier, A De Marco, IATM Ferreira, B Meng, RP Datir, AC Walls, ...
Nature 593 (7857), 136-141, 2021
N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2
M McCallum, A De Marco, FA Lempp, MA Tortorici, D Pinto, AC Walls, ...
Cell 184 (9), 2332-2347. e16, 2021
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
MA Tortorici, M Beltramello, FA Lempp, D Pinto, HV Dang, LE Rosen, ...
Science 370 (6519), 950-957, 2020
Spread of a SARS-CoV-2 variant through Europe in the summer of 2020
EB Hodcroft, M Zuber, S Nadeau, TG Vaughan, KHD Crawford, ...
Nature 595 (7869), 707-712, 2021
SARS-CoV-2 immune evasion by variant B. 1.427/B. 1.429
M McCallum, J Bassi, A De Marco, A Chen, AC Walls, J Di Iulio, ...
BioRxiv, 2021
Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation
M McCallum, AC Walls, JE Bowen, D Corti, D Veesler
Nature structural & molecular biology 27 (10), 942-949, 2020
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park, A Addetia, D Pinto, ...
Nature 597 (7874), 97-102, 2021
Broad sarbecovirus neutralization by a human monoclonal antibody
MA Tortorici, N Czudnochowski, TN Starr, R Marzi, AC Walls, F Zatta, ...
Nature 597 (7874), 103-108, 2021
Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies
FA Lempp, LB Soriaga, M Montiel-Ruiz, F Benigni, J Noack, YJ Park, ...
Nature 598 (7880), 342-347, 2021
Structural basis for broad coronavirus neutralization
MM Sauer, MA Tortorici, YJ Park, AC Walls, L Homad, OJ Acton, ...
Nature Structural & Molecular Biology, 1-9, 2021
Broad betacoronavirus neutralization by a stem helix–specific human antibody
D Pinto, MM Sauer, N Czudnochowski, JS Low, MA Tortorici, MP Housley, ...
Science 373 (6559), 1109-1116, 2021
Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
E Cameroni, JE Bowen, LE Rosen, C Saliba, SK Zepeda, K Culap, ...
Nature, 1-9, 2021
Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants
M McCallum, AC Walls, KR Sprouse, JE Bowen, LE Rosen, HV Dang, ...
Science 374 (6575), 1621-1626, 2021
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
AC Walls, MC Miranda, MN Pham, A Schaefer, A Greaney, ...
bioRxiv, 2021
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy
AJ Greaney, TN Starr, RT Eguia, AN Loes, K Khan, F Karim, S Cele, ...
Biorxiv, 2021
Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
YJ Park, A De Marco, TN Starr, Z Liu, D Pinto, AC Walls, F Zatta, ...
Science, eabm8143, 2021
Multivalent designed proteins protect against SARS-CoV-2 variants of concern
AC Hunt, JB Case, YJ Park, L Cao, K Wu, AC Walls, Z Liu, JE Bowen, ...
bioRxiv, 2021
Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement
M McCallum, N Czudnochowski, LE Rosen, SK Zepeda, JE Bowen, ...
BioRxiv, 2021
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