Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist HM Stoveken, AG Hajduczok, L Xu, GG Tall Proceedings of the National Academy of Sciences 112 (19), 6194-6199, 2015 | 232 | 2015 |
Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells S Giera, R Luo, Y Ying, SD Ackerman, SJ Jeong, HM Stoveken, CJ Folts, ... Elife 7, e33385, 2018 | 110 | 2018 |
Structural basis for regulation of GPR56/ADGRG1 by its alternatively spliced extracellular domains GS Salzman, SD Ackerman, C Ding, A Koide, K Leon, R Luo, ... Neuron 91 (6), 1292-1304, 2016 | 110 | 2016 |
GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force J Yeung, R Adili, EN Stringham, R Luo, A Vizurraga, LK Rosselli-Murai, ... Proceedings of the National Academy of Sciences 117 (45), 28275-28286, 2020 | 68 | 2020 |
Gedunin-and Khivorin-derivatives are small-molecule partial agonists for adhesion G protein-coupled receptors GPR56/ADGRG1 and GPR114/ADGRG5 HM Stoveken, SD Larsen, AV Smrcka, GG Tall Molecular pharmacology 93 (5), 477-488, 2018 | 61 | 2018 |
Dihydromunduletone is a small-molecule selective adhesion G protein–coupled receptor antagonist HM Stoveken, LL Bahr, MW Anders, AP Wojtovich, AV Smrcka, GG Tall Molecular pharmacology 90 (3), 214-224, 2016 | 61 | 2016 |
G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3 S Mathiasen, T Palmisano, NA Perry, HM Stoveken, A Vizurraga, ... Nature chemical biology 16 (12), 1343-1350, 2020 | 51 | 2020 |
Genetic behavioral screen identifies an orphan anti-opioid system D Wang, HM Stoveken, S Zucca, M Dao, C Orlandi, C Song, I Masuho, ... Science 365 (6459), 1267-1273, 2019 | 48 | 2019 |
A comprehensive mutagenesis screen of the adhesion GPCR latrophilin-1/ADGRL1 O Nazarko, A Kibrom, J Winkler, K Leon, H Stoveken, G Salzman, ... IScience 3, 264-278, 2018 | 41 | 2018 |
Genetic variant in human PAR (Protease-Activated Receptor) 4 enhances thrombus formation resulting in resistance to antiplatelet therapeutics BE Tourdot, H Stoveken, D Trumbo, J Yeung, Y Kanthi, LC Edelstein, ... Arteriosclerosis, thrombosis, and vascular biology 38 (7), 1632-1643, 2018 | 39 | 2018 |
The orphan receptor GPR139 signals via Gq/11 to oppose opioid effects HM Stoveken, S Zucca, I Masuho, B Grill, KA Martemyanov Journal of Biological Chemistry 295 (31), 10822-10830, 2020 | 19 | 2020 |
Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange MM Papasergi-Scott, HM Stoveken, L MacConnachie, PY Chan, M Gabay, ... Science Signaling 11 (532), eaap8113, 2018 | 17 | 2018 |
The role of orphan receptor GPR139 in neuropsychiatric behavior M Dao, HM Stoveken, Y Cao, KA Martemyanov Neuropsychopharmacology 47 (4), 902-913, 2022 | 15 | 2022 |
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking N Maza, D Wang, C Kowalski, HM Stoveken, M Dao, OK Sial, AC Giles, ... Nature neuroscience 25 (9), 1179-1190, 2022 | 13 | 2022 |
Identification of Potential Modulators of the RGS7/Gβ5/R7BP Complex HM Stoveken, V Fernandez-Vega, BS Muntean, DN Patil, J Shumate, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (9), 1177-1188, 2021 | 2 | 2021 |
Publisher Correction: G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3 S Mathiasen, T Palmisano, NA Perry, HM Stoveken, A Vizurraga, ... Nature Chemical Biology 16 (12), 1440-1440, 2020 | | 2020 |
Activation of Adhesion G Protein-coupled Receptors by a Tethered Agonist: Mechanism of Action and Pharmacological Modulation HM Stoveken University of Rochester, 2016 | | 2016 |