Darin J. Falk
Darin J. Falk
Assistant Professor, University of Florida
Verified email at
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Cited by
Trolox attenuates mechanical ventilation–induced diaphragmatic dysfunction and proteolysis
JL Betters, DS Criswell, RA Shanely, D Van Gammeren, D Falk, ...
American journal of respiratory and critical care medicine 170 (11), 1179-1184, 2004
Caspase-3 regulation of diaphragm myonuclear domain during mechanical ventilation–induced atrophy
JM McClung, AN Kavazis, KC DeRuisseau, DJ Falk, MA Deering, Y Lee, ...
American journal of respiratory and critical care medicine 175 (2), 150-159, 2007
Ischemia-reperfusion-induced calpain activation and SERCA2a degradation are attenuated by exercise training and calpain inhibition
JP French, JC Quindry, DJ Falk, JL Staib, Y Lee, KKW Wang, SK Powers
American Journal of Physiology-Heart and Circulatory Physiology 290 (1 …, 2006
Antioxidant administration attenuates mechanical ventilation‐induced rat diaphragm muscle atrophy independent of protein kinase B (PKB–Akt) signalling
JM McClung, AN Kavazis, MA Whidden, KC DeRuisseau, DJ Falk, ...
The Journal of physiology 585 (1), 203-215, 2007
Mechanical ventilation induces alterations of the ubiquitin-proteasome pathway in the diaphragm
KC DeRuisseau, AN Kavazis, MA Deering, DJ Falk, D Van Gammeren, ...
Journal of applied physiology 98 (4), 1314-1321, 2005
Characterization of a transgenic short hairpin RNA-induced murine model of Tafazzin deficiency
MS Soustek, DJ Falk, CS Mah, MJ Toth, M Schlame, AS Lewin, BJ Byrne
Human gene therapy 22 (7), 865-871, 2011
Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction
MA Whidden, JM McClung, DJ Falk, MB Hudson, AJ Smuder, WB Nelson, ...
Journal of applied physiology 106 (2), 385-394, 2009
The respiratory neuromuscular system in Pompe disease
DD Fuller, MK ElMallah, BK Smith, M Corti, LA Lawson, DJ Falk, BJ Byrne
Respiratory physiology & neurobiology 189 (2), 241-249, 2013
Pompe disease gene therapy
BJ Byrne, DJ Falk, CA Pacak, S Nayak, RW Herzog, ME Elder, SW Collins, ...
Human molecular genetics 20 (R1), R61-R68, 2011
B-cell depletion is protective against anti-AAV capsid immune response: a human subject case study
M Corti, ME Elder, DJ Falk, L Lawson, BK Smith, S Nayak, TJ Conlon, ...
Molecular Therapy-Methods & Clinical Development 1, 2014
Mechanical ventilation promotes redox status alterations in the diaphragm
DJ Falk, KC DeRuisseau, DL Van Gammeren, MA Deering, AN Kavazis, ...
Journal of applied physiology 101 (4), 1017-1024, 2006
Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation
JM McClung, D Van Gammeren, MA Whidden, DJ Falk, AN Kavazis, ...
Critical care medicine 37 (4), 1373, 2009
Sustained correction of motoneuron histopathology following intramuscular delivery of AAV in pompe mice
MK ElMallah, DJ Falk, S Nayak, RA Federico, MS Sandhu, A Poirier, ...
Molecular Therapy 22 (4), 702-712, 2014
Peripheral nerve and neuromuscular junction pathology in Pompe disease
DJ Falk, AG Todd, S Lee, MS Soustek, MK ElMallah, DD Fuller, ...
Human molecular genetics 24 (3), 625-636, 2015
Redox regulation of diaphragm proteolysis during mechanical ventilation
JM McClung, MA Whidden, AN Kavazis, DJ Falk, KC DeRuisseau, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2008
Gel-mediated delivery of AAV1 vectors corrects ventilatory function in Pompe mice with established disease
CS Mah, DJ Falk, SA Germain, JS Kelley, MA Lewis, DA Cloutier, ...
Molecular Therapy 18 (3), 502-510, 2010
Intrapleural administration of AAV9 improves neural and cardiorespiratory function in Pompe disease
DJ Falk, CS Mah, MS Soustek, KZ Lee, MK ElMallah, DA Cloutier, ...
Molecular Therapy 21 (9), 1661-1667, 2013
Comparative impact of AAV and enzyme replacement therapy on respiratory and cardiac function in adult Pompe mice
DJ Falk, MS Soustek, AG Todd, CS Mah, DA Cloutier, JS Kelley, ...
Molecular Therapy-Methods & Clinical Development 2, 2015
Gene therapy approaches for lysosomal storage disease: next-generation treatment
BJ Byrne, DJ Falk, N Clément, CS Mah
Human gene therapy 23 (8), 808-815, 2012
Correcting N euromuscular D eficits W ith G ene T herapy in P ompe D isease
AG Todd, JA McElroy, RW Grange, DD Fuller, GA Walter, BJ Byrne, ...
Annals of neurology 78 (2), 222-234, 2015
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