C. Dirk Keene, MD, PhD
C. Dirk Keene, MD, PhD
Nancy and Buster Alvord Endowed Chair and Director of Neuropathology, University of Washington
Verified email at - Homepage
Cited by
Cited by
Pluripotency of mesenchymal stem cells derived from adult marrow
Y Jiang, BN Jahagirdar, RL Reinhardt, RE Schwartz, CD Keene, ...
Nature 418 (6893), 41-49, 2002
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
Conserved cell types with divergent features in human versus mouse cortex
RD Hodge, TE Bakken, JA Miller, KA Smith, ER Barkan, LT Graybuck, ...
Nature 573 (7772), 61-68, 2019
Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
LR Zhao, WM Duan, M Reyes, CD Keene, CM Verfaillie, WC Low
Experimental neurology 174 (1), 11-20, 2002
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
PT Nelson, DW Dickson, JQ Trojanowski, CR Jack, PA Boyle, K Arfanakis, ...
Brain 142 (6), 1503-1527, 2019
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy
AC McKee, NJ Cairns, DW Dickson, RD Folkerth, C Dirk Keene, I Litvan, ...
Acta neuropathologica 131, 75-86, 2016
TREM2 haplodeficiency in mice and humans impairs the microglia barrier function leading to decreased amyloid compaction and severe axonal dystrophy
P Yuan, C Condello, CD Keene, Y Wang, TD Bird, SM Paul, W Luo, ...
Neuron 90 (4), 724-739, 2016
An anatomic transcriptional atlas of human glioblastoma
RB Puchalski, N Shah, J Miller, R Dalley, SR Nomura, JG Yoon, KA Smith, ...
Science 360 (6389), 660-663, 2018
Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
DJ Irwin, M Grossman, D Weintraub, HI Hurtig, JE Duda, SX Xie, EB Lee, ...
The Lancet Neurology 16 (1), 55-65, 2017
Association of traumatic brain injury with late-life neurodegenerative conditions and neuropathologic findings
PK Crane, LE Gibbons, K Dams-O’Connor, E Trittschuh, JB Leverenz, ...
JAMA neurology 73 (9), 1062-1069, 2016
Comparative cellular analysis of motor cortex in human, marmoset and mouse
TE Bakken, NL Jorstad, Q Hu, BB Lake, W Tian, BE Kalmbach, M Crow, ...
Nature 598 (7879), 111-119, 2021
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease
CD Keene, CMP Rodrigues, T Eich, MS Chhabra, CJ Steer, WC Low
Proceedings of the National Academy of Sciences 99 (16), 10671-10676, 2002
Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
EM Reiman, JF Arboleda-Velasquez, YT Quiroz, MJ Huentelman, ...
Nature communications 11 (1), 667, 2020
Orbital neoplasms in adults: clinical, radiologic, and pathologic review
TD Tailor, D Gupta, RW Dalley, CD Keene, Y Anzai
Radiographics 33 (6), 1739-1758, 2013
A multimodal cell census and atlas of the mammalian primary motor cortex
Principal manuscript editors, Analysis coordination, ...
Nature 598 (7879), 86-102, 2021
Sex-specific association of apolipoprotein E with cerebrospinal fluid levels of tau
TJ Hohman, L Dumitrescu, LL Barnes, M Thambisetty, G Beecham, ...
JAMA neurology 75 (8), 989-998, 2018
Highly resolved in vivo 1H NMR spectroscopy of the mouse brain at 9.4 T
I Tkáč, PG Henry, P Andersen, CD Keene, WC Low, R Gruetter
Magnetic Resonance in Medicine: An Official Journal of the International …, 2004
Homozygous mutations in CSF1R cause a pediatric-onset leukoencephalopathy and can result in congenital absence of microglia
N Oosterhof, IJ Chang, EG Karimiani, LE Kuil, DM Jensen, R Daza, ...
The American Journal of Human Genetics 104 (5), 936-947, 2019
Thymidine analogs are transferred from prelabeled donor to host cells in the central nervous system after transplantation: a word of caution
TC Burns, XR Ortiz-González, M Gutiérrez-Pérez, CD Keene, R Sharda, ...
Stem cells 24 (4), 1121-1127, 2006
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