| MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors WJ Jessen, SJ Miller, E Jousma, J Wu, TA Rizvi, ME Brundage, D Eaves, ... The Journal of clinical investigation 123 (1), 340-347, 2013 | 364 | 2013 |
| Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer S Kaiser, YK Park, JL Franklin, RB Halberg, M Yu, WJ Jessen, ... Genome biology 8, 1-26, 2007 | 361 | 2007 |
| Activator protein-1 transcription factors are associated with progression and recurrence of prostate cancer X Ouyang, WJ Jessen, H Al-Ahmadie, AM Serio, Y Lin, WJ Shih, ... Cancer research 68 (7), 2132-2144, 2008 | 156 | 2008 |
| Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene SJ Miller, WJ Jessen, T Mehta, A Hardiman, E Sites, S Kaiser, AG Jegga, ... EMBO molecular medicine 1 (4), 236-248, 2009 | 143 | 2009 |
| PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral … VW Keng, EP Rahrmann, AL Watson, BR Tschida, CL Moertel, WJ Jessen, ... Cancer research 72 (13), 3405-3413, 2012 | 97 | 2012 |
| Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3. 1; Pten mutant mice W Banach-Petrosky, WJ Jessen, X Ouyang, H Gao, J Rao, J Quinn, ... Cancer research 67 (19), 9089-9096, 2007 | 97 | 2007 |
| The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer H Shen, N Powers, N Saini, CES Comstock, A Sharma, K Weaver, ... Cancer research 68 (24), 10154-10162, 2008 | 96 | 2008 |
| Ras-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target AV Patel, D Eaves, WJ Jessen, TA Rizvi, JA Ecsedy, MG Qian, BJ Aronow, ... Clinical cancer research 18 (18), 5020-5030, 2012 | 75 | 2012 |
| Active PHO5 chromatin encompasses variable numbers of nucleosomes at individual promoters WJ Jessen, SA Hoose, JA Kilgore, MP Kladde Nature structural & molecular biology 13 (3), 256-263, 2006 | 65 | 2006 |
| Insertional mutagenesis identifies a STAT3/Arid1b/β-catenin pathway driving neurofibroma initiation J Wu, VW Keng, DM Patmore, JJ Kendall, AV Patel, E Jousma, WJ Jessen, ... Cell reports 14 (8), 1979-1990, 2016 | 62 | 2016 |
| Trametinib induces neurofibroma shrinkage and enables surgery P Vaassen, N Dürr, A Röhrig, R Willing, T Rosenbaum Neuropediatrics 50 (05), 300-303, 2019 | 51 | 2019 |
| Cyclin D1 is a selective modifier of androgen-dependent signaling and androgen receptor function CES Comstock, MA Augello, MJ Schiewer, J Karch, CJ Burd, A Ertel, ... Journal of Biological Chemistry 286 (10), 8117-8127, 2011 | 51 | 2011 |
| Targeted cytosine methylation for in vivo detection of protein–DNA interactions CD Carvin, A Dhasarathy, LB Friesenhahn, WJ Jessen, MP Kladde Proceedings of the National Academy of Sciences 100 (13), 7743-7748, 2003 | 45 | 2003 |
| Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2 K Tanaka, A Eskin, F Chareyre, WJ Jessen, J Manent, M Niwa-Kawakita, ... Clinical Cancer Research 19 (14), 3856-3870, 2013 | 41 | 2013 |
| Mapping chromatin structure in vivo using DNA methyltransferases WJ Jessen, A Dhasarathy, SA Hoose, CD Carvin, AL Risinger, MP Kladde Methods 33 (1), 68-80, 2004 | 38 | 2004 |
| Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice JS Fletcher, J Wu, WJ Jessen, J Pundavela, JA Miller, E Dombi, MO Kim, ... JCI insight 4 (3), 2019 | 37 | 2019 |
| Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin TR Hummel, WJ Jessen, SJ Miller, L Kluwe, VF Mautner, MR Wallace, ... Clinical Cancer Research 16 (20), 5048-5057, 2010 | 36 | 2010 |
| Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data X Liu, WJ Jessen, S Sivaganesan, BJ Aronow, M Medvedovic BMC bioinformatics 8, 1-20, 2007 | 34 | 2007 |
| Runx1 contributes to neurofibromatosis type 1 neurofibroma formation H Li, X Zhao, X Yan, WJ Jessen, MO Kim, E Dombi, PP Liu, G Huang, ... Oncogene 35 (11), 1468-1474, 2016 | 24 | 2016 |
| Global methylation profiles in buccal cells of long-term smokers and moist snuff consumers WJ Jessen, MF Borgerding, GL Prasad Biomarkers 23 (7), 625-639, 2018 | 17 | 2018 |
