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Johan Jirholt
Johan Jirholt
RIA iMed, AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
B cell‐deficient mice do not develop type II collagen‐induced arthritis (CIA)
Svensson, Jirholt, Holmdahl, Jansson
Clinical & Experimental Immunology 111 (3), 521-526, 1998
4261998
Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis
M Sundvall, J Jirholt, HT Yang, L Jansson, Å Engström, U Pettersson, ...
Nature genetics 10 (3), 313-317, 1995
2261995
Genetic linkage analysis of collagen‐induced arthritis in the mouse
J Jirholt, A Cook, T Emahazion, M Sundvall, L Jansson, N Nordquist, ...
European journal of immunology 28 (10), 3321-3328, 1998
1651998
Identification of genes controlling collagen-induced arthritis in mice: striking homology with susceptibility loci previously identified in the rat
HT Yang, J Jirholt, L Svensson, M Sundvall, L Jansson, U Pettersson, ...
The Journal of Immunology 163 (5), 2916-2921, 1999
1351999
Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia
B Åsling, J Jirholt, P Hammond, M Knutsson, A Walentinsson, G Davidson, ...
Gut 58 (8), 1063-1069, 2009
1012009
Screening of several H-2 congenic mouse strains identified H-2q mice as highly susceptible to MOG-induced EAE with minimal adjuvant requirement
KB Abdul-Majid, J Jirholt, C Stadelmann, A Stefferl, P Kjellén, E Wallström, ...
Journal of neuroimmunology 111 (1-2), 23-33, 2000
932000
Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases
TR Merriman, HJ Cordell, IA Eaves, PA Danoy, F Coraddu, R Barber, ...
Diabetes 50 (1), 184-194, 2001
802001
Benzoxazepines Achieve Potent Suppression of IL‐17 Release in Human T‐Helper 17 (TH17) Cells through an Induced‐Fit Binding Mode to the Nuclear …
RI Olsson, Y Xue, S von Berg, A Aagaard, J McPheat, EL Hansson, ...
ChemMedChem 11 (2), 207-216, 2016
632016
Retinoid-related orphan receptor γ (RORγ) adult induced knockout mice develop lymphoblastic lymphoma
M Liljevald, M Rehnberg, M Söderberg, M Ramnegård, J Börjesson, ...
Autoimmunity reviews 15 (11), 1062-1070, 2016
542016
The genetics of rheumatoid arthritis and the need for animal models to find and understand the underlying genes
J Jirholt, AKB Lindqvist, R Holmdahl
Arthritis Research & Therapy 3, 1-11, 2001
502001
Potent and orally bioavailable inverse agonists of RORγt resulting from structure-based design
F Narjes, Y Xue, S von Berg, J Malmberg, A Llinas, RI Olsson, J Jirholt, ...
Journal of Medicinal Chemistry 61 (17), 7796-7813, 2018
332018
Identification of susceptibility genes for experimental autoimmune encephalomyelitis that overcome the effect of protective alleles at the eae2 locus
J Jirholt, AK Lindqvist, J Karlsson, Å Andersson, R Holmdahl
International immunology 14 (1), 79-85, 2002
202002
Discovery of potent and orally bioavailable inverse agonists of the retinoic acid receptor-related orphan receptor C2
S von Berg, Y Xue, M Collins, A Llinas, RI Olsson, T Halvarsson, ...
ACS Medicinal Chemistry Letters 10 (6), 972-977, 2019
172019
4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease
J Jirholt, B Åsling, P Hammond, G Davidson, M Knutsson, A Walentinsson, ...
PloS one 6 (4), e19095, 2011
162011
HLA-DR7 and HLA-DQ2: Transgenic mouse strains tested as a model system for ximelagatran hepatotoxicity
H Lundgren, K Martinsson, K Cederbrant, J Jirholt, D Mucs, ...
PloS one 12 (9), e0184744, 2017
142017
AZD0284, a potent, selective, and orally bioavailable inverse agonist of retinoic acid receptor-related orphan receptor C2
F Narjes, A Llinas, S von Berg, J Jirholt, S Lever, R Pehrson, M Collins, ...
Journal of Medicinal Chemistry 64 (18), 13807-13829, 2021
112021
Elucidation of pathways leading to rheumatoid arthritis by genetic analysis of animal models
R Holmdahl, R Bockermann, J Jirholt, A Johansson, P Olofsson, S Lu
Rheumatoid Arthritis 3, 17-35, 2001
72001
The role of lL-17 in the OVA-LPS driven model of lung inflammation
M Rehnberg, M Ramnegård, N Krutrök, L Yrlid, J Jirholt
European Respiratory Journal 46 (suppl 59), 2015
32015
Genetic analysis of murine models for multiple sclerosis
R Holmdahl, J Jirholt, L Jansson, M Sundvall
Human Polygenic Diseases: Animal models. Amsterdam: Harwood Academic …, 1998
31998
Calcineurin-inhibition drives IL13 and IL5 production in differentiating and memory T cells in a Ca++-dependent manner
K Björhall, U Gehrmann, J Jirholt
European Respiratory Journal 52 (suppl 62), 2018
12018
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