Aminopeptidase N (CD13) as a target for cancer chemotherapy M Wickström, R Larsson, P Nygren, J Gullbo Cancer science 102 (3), 501-508, 2011 | 368 | 2011 |
Cyclotides: a novel type of cytotoxic agents P Lindholm, U Göransson, S Johansson, P Claeson, J Gullbo, ... Molecular Cancer Therapeutics 1 (6), 365-369, 2002 | 368 | 2002 |
Cytotoxic Cyclotides from Viola tricolor E Svangård, U Göransson, Z Hocaoglu, J Gullbo, R Larsson, P Claeson, ... Journal of Natural Products 67 (2), 144-147, 2004 | 269 | 2004 |
Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments X Zhang, M Fryknäs, E Hernlund, W Fayad, A De Milito, MH Olofsson, ... Nature communications 5 (1), 3295, 2014 | 243 | 2014 |
APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells N Mohell, J Alfredsson, Å Fransson, M Uustalu, S Byström, J Gullbo, ... Cell death & disease 6 (6), e1794-e1794, 2015 | 186 | 2015 |
Cytotoxicity of digitoxin and related cardiac glycosides in human tumor cells S Johansson, P Lindholm, J Gullbo, R Larsson, L Bohlin, P Claeson Anti-cancer drugs 12 (5), 475-483, 2001 | 168 | 2001 |
Mechanism of action of cytotoxic cyclotides: cycloviolacin O2 disrupts lipid membranes E Svangård, R Burman, S Gunasekera, H Lövborg, J Gullbo, ... Journal of natural products 70 (4), 643-647, 2007 | 166 | 2007 |
The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity A Herrmann, R Burman, JS Mylne, G Karlsson, J Gullbo, DJ Craik, ... Phytochemistry 69 (4), 939-952, 2008 | 164 | 2008 |
Effects of hypoxia on human cancer cell line chemosensitivity S Strese, M Fryknäs, R Larsson, J Gullbo BMC cancer 13, 1-11, 2013 | 157 | 2013 |
Inhibition of proteasome activity, nuclear factor‐KB translocation and cell survival by the antialcoholism drug disulfiram H Lövborg, F Öberg, L Rickardson, J Gullbo, P Nygren, R Larsson International journal of cancer 118 (6), 1577-1580, 2006 | 156 | 2006 |
The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells X Wang, M Mazurkiewicz, EK Hillert, MH Olofsson, S Pierrou, P Hillertz, ... Scientific reports 6 (1), 26979, 2016 | 153 | 2016 |
The traditional medical uses and cytotoxic activities of sixty-one Egyptian plants: discovery of an active cardiac glycoside from Urginea maritima HR El-Seedi, R Burman, A Mansour, Z Turki, L Boulos, J Gullbo, ... Journal of Ethnopharmacology 145 (3), 746-757, 2013 | 150 | 2013 |
Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients M Wickström, K Danielsson, L Rickardson, J Gullbo, P Nygren, A Isaksson, ... Biochemical pharmacology 73 (1), 25-33, 2007 | 138 | 2007 |
Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs J Felth, L Rickardson, J Rosén, M Wickstrom, M Fryknäs, M Lindskog, ... Journal of natural products 72 (11), 1969-1974, 2009 | 126 | 2009 |
Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2 A Herrmann, E Svangård, P Claeson, J Gullbo, L Bohlin, U Göransson Cellular and Molecular Life Sciences CMLS 63, 235-245, 2006 | 118 | 2006 |
Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles L Rickardson, M Fryknäs, S Dhar, H Lövborg, J Gullbo, M Rydåker, ... British journal of cancer 93 (4), 483-492, 2005 | 111 | 2005 |
Synthesis and Evaluation of Derivatives of the Proteasome Deubiquitinase Inhibitor b‐AP 15 X Wang, P D'Arcy, TR Caulfield, A Paulus, K Chitta, C Mohanty, J Gullbo, ... Chemical biology & drug design 86 (5), 1036-1048, 2015 | 102 | 2015 |
Inhibitors and promoters of tubulin polymerization: Synthesis and biological evaluation of chalcones and related dienones as potential anticancer agents C Dyrager, M Wickström, M Fridén-Saxin, A Friberg, K Dahlén, ... Bioorganic & medicinal chemistry 19 (8), 2659-2665, 2011 | 94 | 2011 |
Hsp90 is expressed and represents a therapeutic target in human oesophageal cancer using the inhibitor 17-allylamino-17-demethoxygeldanamycin X Wu, A Wanders, P Wardega, B Tinge, L Gedda, S Bergstrom, L Sooman, ... British journal of cancer 100 (2), 334-343, 2009 | 82 | 2009 |
Melflufen-a peptidase-potentiated alkylating agent in clinical trials M Wickström, P Nygren, R Larsson, J Harmenberg, J Lindberg, P Sjöberg, ... Oncotarget 8 (39), 66641, 2017 | 79 | 2017 |