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Amit Sharma, PhD
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BET proteins promote efficient murine leukemia virus integration at transcription start sites
A Sharma, RC Larue, MR Plumb, N Malani, F Male, A Slaughter, JJ Kessl, ...
Proceedings of the National Academy of Sciences 110 (29), 12036-12041, 2013
2072013
RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions
C Bolinger, A Sharma, D Singh, L Yu, K Boris-Lawrie
Nucleic acids research 38 (5), 1686-1696, 2010
1582010
Molecular mechanisms of retroviral integration site selection
M Kvaratskhelia, A Sharma, RC Larue, E Serrao, A Engelman
Nucleic acids research 42 (16), 10209-10225, 2014
1552014
A new class of multimerization selective inhibitors of HIV-1 integrase
A Sharma, A Slaughter, N Jena, L Feng, JJ Kessl, HJ Fadel, N Malani, ...
PLoS pathogens 10 (5), e1004171, 2014
1382014
The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors
L Feng, A Sharma, A Slaughter, N Jena, Y Koh, N Shkriabai, RC Larue, ...
Journal of Biological Chemistry 288 (22), 15813-15820, 2013
1082013
Thriving under stress: selective translation of HIV-1 structural protein mRNA during Vpr-mediated impairment of eIF4E translation activity
A Sharma, A Yilmaz, K Marsh, A Cochrane, K Boris-Lawrie
PLoS pathogens 8 (3), e1002612, 2012
1002012
Rationally designed ACE2-derived peptides inhibit SARS-CoV-2
RC Larue, E Xing, AD Kenney, Y Zhang, JA Tuazon, J Li, JS Yount, PK Li, ...
Bioconjugate chemistry 32 (1), 215-223, 2020
782020
Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction
S Aiyer, GVT Swapna, N Malani, JM Aramini, WM Schneider, MR Plumb, ...
Nucleic acids research 42 (9), 5917-5928, 2014
762014
Butyrate reprograms expression of specific interferon-stimulated genes
M Chemudupati, AD Kenney, AC Smith, RJ Fillinger, L Zhang, A Zani, ...
Journal of virology 94 (16), 10.1128/jvi. 00326-20, 2020
622020
Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes
RC Larue, MR Plumb, BL Crowe, N Shkriabai, A Sharma, J DiFiore, ...
Nucleic acids research 42 (8), 4868-4881, 2014
462014
The competitive interplay between allosteric HIV-1 integrase inhibitor BI/D and LEDGF/p75 during the early stage of HIV-1 replication adversely affects inhibitor potency
L Feng, V Dharmarajan, E Serrao, A Hoyte, RC Larue, A Slaughter, ...
ACS chemical biology 11 (5), 1313-1321, 2016
412016
Nonsegmented Negative-Sense RNA Viruses Utilize N6-Methyladenosine (m6A) as a Common Strategy To Evade Host Innate Immunity
M Lu, M Xue, HT Wang, EL Kairis, S Ahmad, J Wei, Z Zhang, Q Liu, ...
Journal of virology 95 (9), 10.1128/jvi. 01939-20, 2021
362021
HIV transmission biology: translation for HIV prevention
K Ronen, A Sharma, J Overbaugh
Aids 29 (17), 2219-2227, 2015
362015
Identification of owl monkey CD4 receptors broadly compatible with early-stage HIV-1 isolates
NR Meyerson, A Sharma, GK Wilkerson, J Overbaugh, SL Sawyer
Journal of virology 89 (16), 8611-8622, 2015
292015
Inhibition of SARS-CoV-2 infection by human defensin HNP1 and retrocyclin RC-101
E Kudryashova, A Zani, G Vilmen, A Sharma, W Lu, JS Yount, ...
Journal of molecular biology 434 (6), 167225, 2022
262022
Development of SHIV s with circulating, transmitted HIV‐1 variants
A Sharma, DF Boyd, J Overbaugh
Journal of medical primatology 44 (5), 296-300, 2015
252015
Cellular RNA helicases and HIV-1: insights from genome-wide, proteomic, and molecular studies
CY Chen, X Liu, K Boris-Lawrie, A Sharma, KT Jeang
Virus research 171 (2), 357-365, 2013
232013
The robust restriction of Zika virus by type-I interferon in A549 cells varies by viral lineage and is not determined by IFITM3
TA Gobillot, D Humes, A Sharma, C Kikawa, J Overbaugh
Viruses 12 (5), 503, 2020
202020
5-methylcytosine (m5C) RNA modification controls the innate immune response to virus infection by regulating type I interferons
Y Zhang, LS Zhang, Q Dai, P Chen, M Lu, EL Kairis, V Murugaiah, J Xu, ...
Proceedings of the National Academy of Sciences 119 (42), e2123338119, 2022
192022
Viral RNA N6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus
M Xue, Y Zhang, H Wang, EL Kairis, M Lu, S Ahmad, Z Attia, O Harder, ...
PLoS pathogens 17 (12), e1010142, 2021
192021
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