AAV cis-regulatory sequences are correlated with ocular toxicity W Xiong, DM Wu, Y Xue, SK Wang, MJ Chung, X Ji, P Rana, SR Zhao, ... Proceedings of the National Academy of Sciences 116 (12), 5785-5794, 2019 | 179 | 2019 |
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses YK Chan, SK Wang, CJ Chu, DA Copland, AJ Letizia, H Costa Verdera, ... Science translational medicine 13 (580), eabd3438, 2021 | 133 | 2021 |
CRALBP supports the mammalian retinal visual cycle and cone vision Y Xue, SQ Shen, J Jui, AC Rupp, LC Byrne, S Hattar, JG Flannery, ... The Journal of clinical investigation 125 (2), 727-738, 2015 | 120 | 2015 |
Microglia modulation by TGF-β1 protects cones in mouse models of retinal degeneration SK Wang, Y Xue, CL Cepko The Journal of clinical investigation 130 (8), 4360-4369, 2020 | 58 | 2020 |
Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development D Razafsky, C Ward, C Potter, W Zhu, Y Xue, VJ Kefalov, LG Fong, ... Molecular biology of the cell 27 (12), 1928-1937, 2016 | 42 | 2016 |
Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa SK Wang, Y Xue, P Rana, CM Hong, CL Cepko Proceedings of the National Academy of Sciences 116 (20), 10140-10149, 2019 | 39 | 2019 |
Nrf2 overexpression rescues the RPE in mouse models of retinitis pigmentosa DM Wu, X Ji, MV Ivanchenko, M Chung, M Piper, P Rana, SK Wang, ... JCI insight 6 (2), 2021 | 38 | 2021 |
AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa Y Xue, SK Wang, P Rana, ER West, CM Hong, H Feng, DM Wu, ... elife 10, e66240, 2021 | 32 | 2021 |
Circadian and light-driven regulation of rod dark adaptation Y Xue, S Shen, J Corbo, V Kefalov Scientific Reports 5, 17616, 2015 | 28 | 2015 |
The role of retinol dehydrogenase 10 in the cone visual cycle Y Xue, S Sato, D Razafsky, B Sahu, SQ Shen, C Potter, LL Sandell, ... Scientific reports 7 (1), 2390, 2017 | 18 | 2017 |
Augmentation of CD47/SIRPα signaling protects cones in genetic models of retinal degeneration SK Wang, Y Xue, CL Cepko JCI Insight 6 (16), e150796, 2021 | 8 | 2021 |
Mislocalization of cone nuclei impairs cone function in mice Y Xue, D Razafsky, D Hodizc, VJ Kefalov FASEB journal: official publication of the Federation of American Societies …, 2020 | 6 | 2020 |
Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models Y Xue, X Sun, SK Wang, GB Collin, VJ Kefalov, CL Cepko Proceedings of the National Academy of Sciences 120 (23), e2217885120, 2023 | 3 | 2023 |
Gene Therapies for Retinitis Pigmentosa that Target Glucose Metabolism Y Xue, CL Cepko Cold Spring Harbor Perspectives in Medicine, a041289, 2023 | 2 | 2023 |
Variant txnip compositions and methods of use thereof for the treatment of degenerative ocular diseases Y Xue, CL Cepko US Patent App. 18/017,093, 2023 | | 2023 |
High temporal frequency light response in mouse retina is mediated by ON and OFF bipolar cells and requires FAT3 signaling EC Avilés, SK Wang, S Patel, S Shi, L Lin, VJ Kefalov, LV Goodrich, ... bioRxiv, 2023 | | 2023 |
Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model Y Xue, Y Zhou, CL Cepko bioRxiv, 2023.08. 03.551766, 2023 | | 2023 |
Txnip Gene Therapy of Retinitis Pigmentosa Improves Cone Health Y Xue Retinal Degenerative Diseases XIX: Mechanisms and Experimental Therapy, 143-146, 2023 | | 2023 |
Txnip and ldhb compositions and methods for the treatment of degenerative ocular diseases Y Xue, CL Cepko US Patent App. 17/428,670, 2022 | | 2022 |
Adaptive optics fluorescence lifetime ophthalmoscopy of iGlucoSnFR-TS suggests increased glucose in RPE of rho-/-compared to healthy mice K Kunala, Y Xue, K Huynh, Q Yang, K Parkins, S Steven, A Dubra, ... Investigative Ophthalmology & Visual Science 62 (8), 50-50, 2021 | | 2021 |