C. Ronald Kahn
C. Ronald Kahn
Joslin Diabetes Center and Harvard Medical School
Verified email at - Homepage
Cited by
Cited by
Insulin signalling and the regulation of glucose and lipid metabolism
AR Saltiel, CR Kahn
Nature 414 (6865), 799-806, 2001
Identification and importance of brown adipose tissue in adult humans
AM Cypess, S Lehman, G Williams, I Tal, D Rodman, AB Goldfine, FC Kuo, ...
New England journal of medicine 360 (15), 1509-1517, 2009
Critical nodes in signalling pathways: insights into insulin action
CM Taniguchi, B Emanuelli, CR Kahn
Nature reviews Molecular cell biology 7 (2), 85-96, 2006
Role of brain insulin receptor in control of body weight and reproduction
JC Bruning, D Gautam, DJ Burks, J Gillette, M Schubert, PC Orban, ...
Science 289 (5487), 2122-2125, 2000
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
ME Patti, AJ Butte, S Crunkhorn, K Cusi, R Berria, S Kashyap, Y Miyazaki, ...
Proceedings of the National Academy of Sciences 100 (14), 8466-8471, 2003
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
JC Yoon, P Puigserver, G Chen, J Donovan, Z Wu, J Rhee, G Adelmant, ...
Nature 413 (6852), 131-138, 2001
Type 2 diabetes mellitus
RA DeFronzo, E Ferrannini, L Groop, RR Henry, WH Herman, JJ Holst, ...
Nature reviews Disease primers 1 (1), 1-22, 2015
The insulin signaling system.
MF White, CR Kahn
Journal of biological chemistry 269 (1), 1-4, 1994
Suppression of aging in mice by the hormone Klotho
H Kurosu, M Yamamoto, JD Clark, JV Pastor, A Nandi, P Gurnani, ...
Science 309 (5742), 1829-1833, 2005
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
XJ Sun, P Rothenberg, CR Kahn, JM Backer, E Araki, PA Wilden, ...
Nature 352 (6330), 73-77, 1991
Developmental origin of fat: tracking obesity to its source
S Gesta, YH Tseng, CR Kahn
Cell 131 (2), 242-256, 2007
Antioxidants prevent health-promoting effects of physical exercise in humans
M Ristow, K Zarse, A Oberbach, N Klöting, M Birringer, M Kiehntopf, ...
Proceedings of the National Academy of Sciences 106 (21), 8665-8670, 2009
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
MD Hirschey, T Shimazu, E Goetzman, E Jing, B Schwer, DB Lombard, ...
Nature 464 (7285), 121-125, 2010
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
E Araki, MA Lipes, ME Patti, JC Brüning, B Haag III, RS Johnson, ...
Nature 372 (6502), 186-190, 1994
Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study
BC Martin, JH Warram, AS Krolewski, JS Soeldner, CR Kahn, ...
The Lancet 340 (8825), 925-929, 1992
Insulin receptor signaling in normal and insulin-resistant states
J Boucher, A Kleinridders, CR Kahn
Cold Spring Harbor perspectives in biology 6 (1), a009191, 2014
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
MD Michael, RN Kulkarni, C Postic, SF Previs, GI Shulman, ...
Molecular cell 6 (1), 87-97, 2000
Extended longevity in mice lacking the insulin receptor in adipose tissue
M Bluher, BB Kahn, CR Kahn
Science 299 (5606), 572-574, 2003
Insulin resistance differentially affects the PI 3-kinase–and MAP kinase–mediated signaling in human muscle
K Cusi, K Maezono, A Osman, M Pendergrass, ME Patti, T Pratipanawatr, ...
The Journal of clinical investigation 105 (3), 311-320, 2000
Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes
RN Kulkarni, JC Brüning, JN Winnay, C Postic, MA Magnuson, CR Kahn
Cell 96 (3), 329-339, 1999
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