AI-based structure prediction empowers integrative structural analysis of human nuclear pores S Mosalaganti, A Obarska-Kosinska, M Siggel, R Taniguchi, B Turoňová, ... Science 376 (6598), eabm9506, 2022 | 218* | 2022 |
Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex X Wu, M Siggel, S Ovchinnikov, W Mi, V Svetlov, E Nudler, M Liao, ... Science 368 (6489), eaaz2449, 2020 | 198 | 2020 |
Dynamic cluster formation determines viscosity and diffusion in dense protein solutions S von Bülow, M Siggel, M Linke, G Hummer Proceedings of the National Academy of Sciences 116 (20), 9843-9852, 2019 | 155 | 2019 |
PyContact: rapid, customizable, and visual analysis of noncovalent interactions in MD simulations M Scheurer, P Rodenkirch, M Siggel, RC Bernardi, K Schulten, ... Biophysical journal 114 (3), 577-583, 2018 | 100 | 2018 |
Visualizing the disordered nuclear transport machinery in situ M Yu, M Heidari, S Mikhaleva, PS Tan, S Mingu, H Ruan, ... Nature 617 (7959), 162-169, 2023 | 61* | 2023 |
Antimalarial inhibitors targeting serine hydroxymethyltransferase (SHMT) with in vivo efficacy and analysis of their binding mode based on X-ray cocrystal structures G Schwertz, MC Witschel, M Rottmann, R Bonnert, U Leartsakulpanich, ... Journal of medicinal chemistry 60 (12), 4840-4860, 2017 | 48 | 2017 |
Variable microtubule architecture in the malaria parasite JL Ferreira, V Pražák, D Vasishtan, M Siggel, F Hentzschel, AM Binder, ... Nature Communications 14 (1), 1216, 2023 | 35* | 2023 |
Membrane fusion and drug delivery with carbon nanotube porins NT Ho, M Siggel, KV Camacho, RM Bhaskara, JM Hicks, YC Yao, ... Proceedings of the National Academy of Sciences 118 (19), e2016974118, 2021 | 35 | 2021 |
FAM134B-RHD protein clustering drives spontaneous budding of asymmetric membranes M Siggel, RM Bhaskara, MK Moesser, I Dikic, G Hummer The Journal of Physical Chemistry Letters 12 (7), 1926-1931, 2021 | 28 | 2021 |
MDBenchmark: A toolkit to optimize the performance of molecular dynamics simulations M Gecht, M Siggel, M Linke, G Hummer, J Köfinger The Journal of Chemical Physics 153 (14), 2020 | 20 | 2020 |
Phospholipid scramblases remodel the shape of asymmetric membranes M Siggel, RM Bhaskara, G Hummer The Journal of Physical Chemistry Letters 10 (20), 6351-6354, 2019 | 16 | 2019 |
TriMem: A parallelized hybrid Monte Carlo software for efficient simulations of lipid membranes M Siggel, S Kehl, K Reuter, J Köfinger, G Hummer The journal of chemical physics 157 (17), 2022 | 12 | 2022 |
Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles E Sitarska, SD Almeida, MS Beckwith, J Stopp, J Czuchnowski, M Siggel, ... Nature Communications 14 (1), 5644, 2023 | 11 | 2023 |
Tracking of fluorescently labeled polymer particles reveals surface effects during shear-controlled aggregation S Caimi, A Cingolani, B Jaquet, M Siggel, M Lattuada, M Morbidelli Langmuir 33 (49), 14038-14044, 2017 | 11 | 2017 |
PyTME (Python Template Matching Engine): A fast, flexible, and multi-purpose template matching library for cryogenic electron microscopy data VJ Maurer, M Siggel, J Kosinski SoftwareX 25, 101636, 2024 | 9 | 2024 |
The distance between the plasma membrane and the actomyosin cortex acts as a nanogate to control cell surface mechanics S Lembo, L Strauss, D Cheng, J Vermeil, M Siggel, M Toro-Nahuelpan, ... BioRxiv, 2023.01. 31.526409, 2023 | 8 | 2023 |
ColabSeg: An interactive tool for editing, processing, and visualizing membrane segmentations from cryo-ET data M Siggel, RK Jensen, VJ Maurer, J Mahamid, J Kosinski Journal of Structural Biology 216 (2), 108067, 2024 | 4 | 2024 |
What shapes template‐matching performance in cryogenic electron tomography in situ? VJ Maurer, M Siggel, J Kosinski Acta Crystallographica Section D: Structural Biology, 2024 | 2* | 2024 |
Nanotube-vesicle compositions and uses thereof A Noy, NT HO, G Hummer, M Siggel US Patent App. 17/121,578, 2021 | 1 | 2021 |
Integrative Structural Analysis of Human Nuclear Pore Complex S Mosalaganti, A Obarska-Kosinska, M Siggel, R Taniguchi, B Turoňová, ... Microscopy and Microanalysis 28 (S1), 1114-1114, 2022 | | 2022 |