Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis L Duan, Y Miura, M Dimri, B Majumder, IL Dodge, AL Reddi, A Ghosh, ... Journal of Biological Chemistry 278 (31), 28950-28960, 2003 | 272 | 2003 |
The Cbl family and other ubiquitin ligases: destructive forces in control of antigen receptor signaling L Duan, AL Reddi, A Ghosh, M Dimri, H Band Immunity 21 (1), 7-17, 2004 | 164 | 2004 |
Cytosolic phospholipase A2 participates with TNF-α in the induction of apoptosis of human macrophages infected with Mycobacterium tuberculosis H37Ra L Duan, H Gan, J Arm, HG Remold The Journal of Immunology 166 (12), 7469-7476, 2001 | 138 | 2001 |
Critical role of mitochondrial damage in determining outcome of macrophage infection with Mycobacterium tuberculosis L Duan, H Gan, DE Golan, HG Remold The Journal of Immunology 169 (9), 5181-5187, 2002 | 111 | 2002 |
Modeling breast cancer–associated c-Src and EGFR overexpression in human MECs: c-Src and EGFR cooperatively promote aberrant three-dimensional acinar structure and invasive … M Dimri, M Naramura, L Duan, J Chen, C Ortega-Cava, G Chen, ... Cancer research 67 (9), 4164-4172, 2007 | 105 | 2007 |
Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers SM Raja, RJ Clubb, C Ortega-Cava, SH Williams, TA Bailey, L Duan, ... Cancer biology & therapy 11 (2), 263-276, 2011 | 82 | 2011 |
Cbl-mediated ubiquitinylation and negative regulation of Vav Y Miura-Shimura, L Duan, NL Rao, AL Reddi, H Shimura, R Rottapel, ... Journal of Biological Chemistry 278 (40), 38495-38504, 2003 | 79 | 2003 |
A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCγ1 activation and angiogenesis AJ Singh, RD Meyer, G Navruzbekov, R Shelke, L Duan, H Band, ... Proceedings of the National Academy of Sciences 104 (13), 5413-5418, 2007 | 75 | 2007 |
Enhancement of antimycobacterial activity of macrophages by stabilization of inner mitochondrial membrane potential H Gan, X He, L Duan, E Mirabile-Levens, H Kornfeld, HG Remold The Journal of infectious diseases 191 (8), 1292-1300, 2005 | 63 | 2005 |
Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration L Duan, SM Raja, G Chen, S Virmani, SH Williams, RJ Clubb, ... Journal of biological chemistry 286 (1), 620-633, 2011 | 57 | 2011 |
Overexpression of RhoA induces preneoplastic transformation of primary mammary epithelial cells X Zhao, L Lu, N Pokhriyal, H Ma, L Duan, S Lin, N Jafari, H Band, V Band Cancer research 69 (2), 483-491, 2009 | 55 | 2009 |
p53-regulated autophagy is controlled by glycolysis and determines cell fate L Duan, RE Perez, B Davaadelger, EN Dedkova, LA Blatter, CG Maki Oncotarget 6 (27), 23135, 2015 | 52 | 2015 |
Binding of Cbl to a phospholipase Cγ1-docking site on platelet-derived growth factor receptor β provides a dual mechanism of negative regulation AL Reddi, GG Ying, L Duan, G Chen, M Dimri, P Douillard, BJ Druker, ... Journal of biological chemistry 282 (40), 29336-29347, 2007 | 52 | 2007 |
Prolylcarboxypeptidase regulates proliferation, autophagy, and resistance to 4-hydroxytamoxifen-induced cytotoxicity in estrogen receptor-positive breast cancer cells L Duan, N Motchoulski, B Danzer, I Davidovich, Z Shariat-Madar, ... Journal of biological chemistry 286 (4), 2864-2876, 2011 | 43 | 2011 |
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1 L Duan, RE Perez, M Hansen, S Gitelis, CG Maki Cancer biology & therapy 15 (12), 1600-1612, 2014 | 35 | 2014 |
Distinct roles for Rho versus Rac/Cdc42 GTPases downstream of Vav2 in regulating mammary epithelial acinar architecture L Duan, G Chen, S Virmani, GG Ying, SM Raja, BM Chung, MA Rainey, ... Journal of biological chemistry 285 (2), 1555-1568, 2010 | 34 | 2010 |
The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT L Duan, G Ying, B Danzer, RE Perez, Z Shariat-Madar, VV Levenson, ... Journal of Biological Chemistry 289 (31), 21694-21705, 2014 | 30 | 2014 |
The IGF-1R/AKT pathway determines cell fate in response to p53 L Duan, CG Maki Translational cancer research 5 (6), 664, 2016 | 29 | 2016 |
Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor B Davaadelger, L Duan, RE Perez, S Gitelis, CG Maki Oncotarget 7 (19), 27511, 2016 | 29 | 2016 |
Biochemical basis for the requirement of kinase activity for Cbl-dependent ubiquitinylation and degradation of a target tyrosine kinase AK Ghosh, AL Reddi, NL Rao, L Duan, V Band, H Band Journal of Biological Chemistry 279 (34), 36132-36141, 2004 | 28 | 2004 |