Lisa Breckels (née Simpson)
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A subcellular map of the human proteome
PJ Thul, L Åkesson, M Wiking, D Mahdessian, A Geladaki, H Ait Blal, ...
Science 356 (6340), eaal3321, 2017
A draft map of the mouse pluripotent stem cell spatial proteome
A Christoforou, CM Mulvey, LM Breckels, A Geladaki, T Hurrell, ...
Nature communications 7 (1), 9992, 2016
A comprehensive subcellular atlas of the Toxoplasma proteome via hyperLOPIT provides spatial context for protein functions
K Barylyuk, L Koreny, H Ke, S Butterworth, OM Crook, I Lassadi, V Gupta, ...
Cell host & microbe 28 (5), 752-766. e9, 2020
Combining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics
A Geladaki, N Kočevar Britovšek, LM Breckels, TS Smith, OL Vennard, ...
Nature communications 10 (1), 331, 2019
Using hyperLOPIT to perform high-resolution mapping of the spatial proteome
CM Mulvey, LM Breckels, A Geladaki, NK Britovšek, DJH Nightingale, ...
Nature protocols 12 (6), 1110-1135, 2017
Mass-spectrometry-based spatial proteomics data analysis using pRoloc and pRolocdata
L Gatto, LM Breckels, S Wieczorek, T Burger, KS Lilley
Bioinformatics 30 (9), 1322-1324, 2014
Deciphering thylakoid sub-compartments using a mass spectrometry-based approach
M Tomizioli, C Lazar, S Brugière, T Burger, D Salvi, L Gatto, L Moyet, ...
Molecular & Cellular Proteomics 13 (8), 2147-2167, 2014
The effect of organelle discovery upon sub-cellular protein localisation
LM Breckels, L Gatto, A Christoforou, AJ Groen, KS Lilley, MWB Trotter
Journal of proteomics 88, 129-140, 2013
Identification of Trans-Golgi Network Proteins in Arabidopsis thaliana Root Tissue
AJ Groen, G Sancho-Andres, LM Breckels, L Gatto, F Aniento, KS Lilley
Journal of proteome research 13 (2), 763-776, 2014
Bioinformatics and molecular modelling approaches to GPCR oligomerization
LM Simpson, B Taddese, ID Wall, CA Reynolds
Current opinion in pharmacology 10 (1), 30-37, 2010
A subcellular map of the human proteome. Science 356: eaal3321
PJ Thul, L Åkesson, M Wiking, D Mahdessian, A Geladaki, H Ait Blal, ...
Learning from heterogeneous data sources: an application in spatial proteomics
LM Breckels, SB Holden, D Wojnar, CM Mulvey, A Christoforou, A Groen, ...
PLoS computational biology 12 (5), e1004920, 2016
Visualization of proteomics data using R and Bioconductor
L Gatto, LM Breckels, T Naake, S Gibb
Proteomics 15 (8), 1375-1389, 2015
A foundation for reliable spatial proteomics data analysis
L Gatto, LM Breckels, T Burger, DJH Nightingale, AJ Groen, C Campbell, ...
Molecular & Cellular Proteomics 13 (8), 1937-1952, 2014
Proteome mapping of a cyanobacterium reveals distinct compartment organization and cell-dispersed metabolism
LL Baers, LM Breckels, LA Mills, L Gatto, MJ Deery, TJ Stevens, CJ Howe, ...
Plant Physiology 181 (4), 1721-1738, 2019
A Bioconductor workflow for processing and analysing spatial proteomics data
LM Breckels, CM Mulvey, KS Lilley, L Gatto
F1000Research 5, 2016
Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
JJH Shin, OM Crook, AC Borgeaud, J Cattin-Ortolá, SY Peak-Chew, ...
Nature communications 11 (1), 5987, 2020
Modeling GPCR active state conformations: The β2‐adrenergic receptor
LM Simpson, ID Wall, FE Blaney, CA Reynolds
Proteins: Structure, Function, and Bioinformatics 79 (5), 1441-1457, 2011
Assessing sub-cellular resolution in spatial proteomics experiments
L Gatto, LM Breckels, KS Lilley
Current opinion in chemical biology 48, 123-149, 2019
Spatiotemporal proteomic profiling of the pro-inflammatory response to lipopolysaccharide in the THP-1 human leukaemia cell line
CM Mulvey, LM Breckels, OM Crook, DJ Sanders, ALR Ribeiro, ...
Nature Communications 12 (1), 5773, 2021
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Articles 1–20