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Rab Prinjha
Rab Prinjha
Former Head of Immunology Research GSK
Verified email at gsk.com
Title
Cited by
Cited by
Year
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ...
Nature 478 (7370), 529-533, 2011
17092011
Suppression of inflammation by a synthetic histone mimic
E Nicodeme, KL Jeffrey, U Schaefer, S Beinke, S Dewell, C Chung, ...
Nature 468 (7327), 1119-1123, 2010
16872010
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
JP Cogswell, J Ward, IA Taylor, M Waters, Y Shi, B Cannon, K Kelnar, ...
Journal of Alzheimer's disease 14 (1), 27-41, 2008
10962008
Inhibitor of neurite outgrowth in humans
WFS Prinjha R, Moore SE, Vinson M, Blake S, Morrow R, Christie G ...
Nature 403, 383-4, 2000
8812000
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
MU Kaikkonen, NJ Spann, S Heinz, CE Romanoski, KA Allison, ...
Molecular cell 51 (3), 310-325, 2013
7092013
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation
HD Lewis, J Liddle, JE Coote, SJ Atkinson, MD Barker, BD Bax, KL Bicker, ...
Nature chemical biology 11 (3), 189-191, 2015
6562015
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
H Li, S Wetten, L Li, PLS Jean, R Upmanyu, L Surh, D Hosford, ...
Archives of neurology 65 (1), 45-53, 2008
5932008
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
SE Baranzini, J Wang, RA Gibson, N Galwey, Y Naegelin, F Barkhof, ...
Human molecular genetics 18 (4), 767-778, 2009
5772009
BET inhibitor resistance emerges from leukaemia stem cells
CY Fong, O Gilan, EYN Lam, AF Rubin, S Ftouni, D Tyler, K Stanley, ...
Nature 525 (7570), 538-542, 2015
5192015
Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins
RJ Giger, JF Cloutier, A Sahay, RK Prinjha, DV Levengood, SE Moore, ...
Neuron 25 (1), 29-41, 2000
5122000
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer
ML Burr, CE Sparbier, KL Chan, YC Chan, A Kersbergen, EYN Lam, ...
Cancer cell 36 (4), 385-401. e8, 2019
4552019
Discovery and characterization of small molecule inhibitors of the BET family bromodomains
C Chung, H Coste, JH White, O Mirguet, J Wilde, RL Gosmini, C Delves, ...
Journal of medicinal chemistry 54 (11), 3827-3838, 2011
4272011
Broadly neutralizing antibodies and viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice
A Halper-Stromberg, CL Lu, F Klein, JA Horwitz, S Bournazos, L Nogueira, ...
Cell 158 (5), 989-999, 2014
4192014
Cloning and functional expression of a human orthologue of rat vanilloid receptor-1
P Hayes, HJ Meadows, MJ Gunthorpe, MH Harries, MD Duckworth, ...
Pain 88 (2), 205-215, 2000
3912000
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
P Ntziachristos, A Tsirigos, GG Welstead, T Trimarchi, S Bakogianni, L Xu, ...
Nature 514 (7523), 513-517, 2014
3832014
Discovery of epigenetic regulator I-BET762: lead optimization to afford a clinical candidate inhibitor of the BET bromodomains
O Mirguet, R Gosmini, J Toum, CA Clément, M Barnathan, JM Brusq, ...
Journal of medicinal chemistry 56 (19), 7501-7515, 2013
3492013
Suppression of the antiviral response by an influenza histone mimic
I Marazzi, JSY Ho, J Kim, B Manicassamy, S Dewell, RA Albrecht, ...
Nature 483 (7390), 428-433, 2012
3292012
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation
O Gilan, I Rioja, K Knezevic, MJ Bell, MM Yeung, NR Harker, EYN Lam, ...
Science 368 (6489), 387-394, 2020
3122020
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
D Levy, AJ Kuo, Y Chang, U Schaefer, C Kitson, P Cheung, A Espejo, ...
Nature immunology 12 (1), 29, 2011
2912011
Place your BETs: the therapeutic potential of bromodomains
RK Prinjha, J Witherington, K Lee
Trends in pharmacological sciences 33 (3), 146-153, 2012
2752012
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Articles 1–20