| A PfRH5-based vaccine is efficacious against heterologous strain blood-stage Plasmodium falciparum infection in aotus monkeys AD Douglas, GC Baldeviano, CM Lucas, LA Lugo-Roman, C Crosnier, ... Cell host & microbe 17 (1), 130-139, 2015 | 266 | 2015 |
| Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5 AD Douglas, AR Williams, E Knuepfer, JJ Illingworth, JM Furze, ... The Journal of Immunology 192 (1), 245-258, 2014 | 179 | 2014 |
| Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions RO Payne, SE Silk, SC Elias, K Miura, A Diouf, F Galaway, H De Graaf, ... JCI insight 2 (21), 2017 | 153 | 2017 |
| Human antibodies that slow erythrocyte invasion potentiate malaria-neutralizing antibodies DGW Alanine, D Quinkert, R Kumarasingha, S Mehmood, FR Donnellan, ... Cell 178 (1), 216-228. e21, 2019 | 148 | 2019 |
| Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies RO Payne, SE Silk, SC Elias, KH Milne, TA Rawlinson, D Llewellyn, ... JCI insight 2 (12), 2017 | 109 | 2017 |
| Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial SH Hodgson, P Choudhary, SC Elias, KH Milne, TW Rampling, S Biswas, ... Molecular Therapy 22 (12), 2142-2154, 2014 | 78 | 2014 |
| Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system KA Hjerrild, J Jin, KE Wright, RE Brown, JM Marshall, GM Labbé, SE Silk, ... Scientific reports 6 (1), 30357, 2016 | 72 | 2016 |
| A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates AD Douglas, GC Baldeviano, J Jin, K Miura, A Diouf, ZA Zenonos, ... Nature communications 10 (1), 1953, 2019 | 70 | 2019 |
| Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody TA Rawlinson, NM Barber, F Mohring, JS Cho, V Kosaisavee, SF Gérard, ... Nature microbiology 4 (9), 1497-1507, 2019 | 62 | 2019 |
| Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of … L Foquet, C Schafer, NK Minkah, DGW Alanine, EL Flannery, RWJ Steel, ... Frontiers in immunology 9, 524, 2018 | 52 | 2018 |
| Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens JJ Illingworth, DG Alanine, R Brown, JM Marshall, HE Bartlett, SE Silk, ... Frontiers in immunology 10, 1254, 2019 | 48 | 2019 |
| Heterotypic interactions drive antibody synergy against a malaria vaccine candidate RJ Ragotte, D Pulido, AM Lias, D Quinkert, DGW Alanine, A Jamwal, ... Nature communications 13 (1), 933, 2022 | 34 | 2022 |
| Use of Humanised Rat Basophilic Leukaemia Cell Line RS-ATL8 for the Assessment of Allergenicity of Schistosoma mansoni Proteins D Wan, F Ludolf, DGW Alanine, O Stretton, E Ali Ali, N Al-Barwary, ... PLoS Neglected Tropical Diseases 8 (9), e3124, 2014 | 27 | 2014 |
| Functional characterization and comparison of Plasmodium falciparum proteins as targets of transmission-blocking antibodies D Nikolaeva, JJ Illingworth, K Miura, DGW Alanine, IJ Brian, Y Li, AJ Fyfe, ... Molecular & Cellular Proteomics 19 (1), 155-166, 2020 | 24 | 2020 |
| Antibodies from malaria-exposed Malians generally interact additively or synergistically with human vaccine-induced RH5 antibodies AC Willcox, AS Huber, A Diouf, JR Barrett, SE Silk, D Pulido, LDW King, ... Cell Reports Medicine 2 (7), 2021 | 9 | 2021 |
| Characterization of human FcεRIα chain expression and gene copy number in humanized rat basophilic leukaemia (RBL) reporter cell lines EA Ali, M Kalli, D Wan, R Nakamura, D Onion, DGW Alanine, MJC Alcocer, ... PLoS One 14 (8), e0221034, 2019 | 9 | 2019 |
| Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex BG Williams, LDW King, D Pulido, D Quinkert, AM Lias, SE Silk, ... Nature Communications 15 (1), 4857, 2024 | 6 | 2024 |
| Therapeutic antibodies DGW Alanine, MR Goulart US Patent App. 18/417,116, 2024 | | 2024 |
| Treatment and prevention of malaria S Draper, M Higgins, DGW Alanine US Patent App. 17/284,617, 2022 | | 2022 |
| Adeno‐associated viral vectored delivery of a monoclonal antibody gene against blood‐stage malaria M Bardelli, D Alanine, F Donnellan, D Quinkert, J Marshall, S Draper Human Gene Therapy 30 (8), 2019 | | 2019 |
Simon J DraperProfessor of Vaccinology and Translational Medicine, University of OxfordVerified email at paediatrics.ox.ac.uk
