| Spatially resolved, highly multiplexed RNA profiling in single cells KH Chen*, AN Boettiger*, JR Moffitt*, S Wang, X Zhuang Science 348 (6233), aaa6090, *equal authorship, 2015 | 2431 | 2015 |
| Recent advances in optical tweezers JR Moffitt, YR Chemla, SB Smith, C Bustamante Annu. Rev. Biochem. 77, 205-228, 2008 | 1397 | 2008 |
| Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region JR Moffitt, D Bambah-Mukku, SW Eichhorn, E Vaughn, K Shekhar, ... Science 362 (6416), eaau5324, 2018 | 1065 | 2018 |
| Super-resolution imaging reveals distinct chromatin folding for different epigenetic states AN Boettiger, B Bintu, JR Moffitt, S Wang, BJ Beliveau, G Fudenberg, ... Nature 529 (7586), 418-422, 2016 | 893 | 2016 |
| Spatial organization of chromatin domains and compartments in single chromosomes S Wang, JH Su, BJ Beliveau, B Bintu, JR Moffitt, C Wu, X Zhuang Biophysical Journal 112 (3), 217a, 2017 | 682 | 2017 |
| High-throughput single-cell gene-expression profiling with multiplexed error-robust fluorescence in situ hybridization JR Moffitt*`, J Hao`, G Wang`, KH Chen, HP Babcock, X Zhuang* Proceedings of the National Academy of Sciences 113 (39), *co-corresponding …, 2016 | 518 | 2016 |
| Characterization and development of photoactivatable fluorescent proteins for single-molecule–based superresolution imaging S Wang, JR Moffitt, GT Dempsey, XS Xie, X Zhuang Proceedings of the National Academy of Sciences 111 (23), 8452-8457, 2014 | 407 | 2014 |
| MAFG-driven astrocytes promote CNS inflammation MA Wheeler, IC Clark, EC Tjon, Z Li, SEJ Zandee, CP Couturier, ... Nature 578 (7796), 593-599, 2020 | 404 | 2020 |
| Differential detection of dual traps improves the spatial resolution of optical tweezers JR Moffitt*, YR Chemla*, D Izhaky, C Bustamante Proceedings of the National Academy of Sciences 103 (24), 9006, *equal …, 2006 | 387 | 2006 |
| Intersubunit coordination in a homomeric ring ATPase JR Moffitt*, YR Chemla*, K Aathavan, S Grimes, PJ Jardine, DL Anderson, ... Nature 457 (7228), 446-450, *equal authorship, 2009 | 342 | 2009 |
| High-performance multiplexed fluorescence in situ hybridization in culture and tissue with matrix imprinting and clearing JR Moffitt, J Hao, D Bambah-Mukku, T Lu, C Dulac, X Zhuang Proceedings of the National Academy of Sciences 113 (50), 14456-14461, 2016 | 304 | 2016 |
| The emerging landscape of spatial profiling technologies JR Moffitt, E Lundberg, H Heyn Nature Reviews Genetics 23 (12), 741-759, 2022 | 264 | 2022 |
| Multiplexed imaging of high-density libraries of RNAs with MERFISH and expansion microscopy G Wang, JR Moffitt, X Zhuang Scientific reports 8 (1), 4847, 2018 | 257 | 2018 |
| The single-cell chemostat: an agarose-based, microfluidic device for high-throughput, single-cell studies of bacteria and bacterial communities JR Moffitt*, JB Lee*, P Cluzel Lab Chip, *equal authorship, 2012 | 243 | 2012 |
| Cell segmentation in imaging-based spatial transcriptomics V Petukhov, RJ Xu, RA Soldatov, P Cadinu, K Khodosevich, JR Moffitt, ... Nature biotechnology 40 (3), 345-354, 2022 | 240 | 2022 |
| RNA Imaging with Multiplexed Error-Robust Fluorescence In Situ Hybridization (MERFISH) JR Moffitt*, X Zhuang* Methods in Enzymology, *corresponding author, 2016 | 220 | 2016 |
| Time-gating improves the spatial resolution of STED microscopy JR Moffitt*, C Osseforth, J Michaelis* Optics express 19 (5), 4242-4254, *co-corresponding author, 2011 | 178 | 2011 |
| Single–base pair unwinding and asynchronous RNA release by the hepatitis C virus NS3 helicase W Cheng, SG Arunajadai, JR Moffitt, I Tinoco Jr, C Bustamante Science 333 (6050), 1746-1749, 2011 | 170 | 2011 |
| Robust circadian oscillations in growing cyanobacteria require transcriptional feedback SW Teng, S Mukherji*, JR Moffitt*, S De Buyl*, EK O’shea Science 340 (6133), 737-740, *equal authorship, 2013 | 166 | 2013 |
| Spatial organization shapes the turnover of a bacterial transcriptome JR Moffitt, S Pandey, AN Boettiger, S Wang, X Zhuang elife 5, e13065, 2016 | 158 | 2016 |
Xiaowei ZhuangProfessor of Chemistry and Chemical Biology, Harvard UniversityVerified email at chemistry.harvard.edu
