| A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function CL Araya, DM Fowler, W Chen, I Muniez, JW Kelly, S Fields Proceedings of the National Academy of Sciences, 2012 | 282 | 2012 |
| “Inverse drug discovery” strategy to identify proteins that are targeted by latent electrophiles as exemplified by aryl fluorosulfates DE Mortenson, GJ Brighty, L Plate, G Bare, W Chen, S Li, H Wang, ... Journal of the American Chemical Society 140 (1), 200-210, 2018 | 261 | 2018 |
| Arylfluorosulfates inactivate intracellular lipid binding protein (s) through chemoselective SuFEx reaction with a binding site Tyr residue W Chen, J Dong, L Plate, DE Mortenson, GJ Brighty, S Li, Y Liu, ... Journal of the American Chemical Society 138 (23), 7353-7364, 2016 | 251 | 2016 |
| Structural and energetic basis of carbohydrate–aromatic packing interactions in proteins W Chen, S Enck, JL Price, DL Powers, ET Powers, CH Wong, HJ Dyson, ... Journal of the American Chemical Society 135 (26), 9877-9884, 2013 | 106 | 2013 |
| A novel method for high‐level production of TEV protease by superfolder GFP Tag X Wu, D Wu, Z Lu, W Chen, X Hu, Y Ding BioMed Research International 2009 (1), 591923, 2009 | 88 | 2009 |
| N‐glycosylation of enhanced aromatic sequons to increase glycoprotein stability JL Price, EK Culyba, W Chen, AN Murray, SR Hanson, CH Wong, ... Peptide Science 98 (3), 195-211, 2012 | 64 | 2012 |
| Synthesis of Sulfotyrosine‐Containing Peptides by Incorporating Fluorosulfated Tyrosine Using an Fmoc‐Based Solid‐Phase Strategy W Chen, J Dong, S Li, Y Liu, Y Wang, L Yoon, P Wu, KB Sharpless, ... Angewandte Chemie 128 (5), 1867-1870, 2016 | 60 | 2016 |
| Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon W Chen, L Kong, S Connelly, JM Dendle, Y Liu, IA Wilson, ET Powers, ... ACS chemical biology 11 (7), 1852-1861, 2016 | 52 | 2016 |
| Enhanced aromatic sequons increase oligosaccharyltransferase glycosylation efficiency and glycan homogeneity AN Murray, W Chen, A Antonopoulos, SR Hanson, RL Wiseman, A Dell, ... Chemistry & biology 22 (8), 1052-1062, 2015 | 51 | 2015 |
| Fluorescence turn-on folding sensor to monitor proteome stress in live cells Y Liu, X Zhang, W Chen, YL Tan, JW Kelly Journal of the American Chemical Society 137 (35), 11303-11311, 2015 | 37 | 2015 |
| A novel method for high-level production of psychrophilic TAB5 alkaline phosphatase Z Lu, W Chen, R Liu, X Hu, Y Ding Protein Expression and Purification 74 (2), 217-222, 2010 | 27 | 2010 |
| Engineering improved antiphosphotyrosine antibodies based on an immunoconvergent binding motif Y Mou, XX Zhou, K Leung, AJ Martinko, JY Yu, W Chen, JA Wells Journal of the American Chemical Society 140 (48), 16615-16624, 2018 | 24 | 2018 |
| Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy W Chen, KY Mou, P Solomon, R Aggarwal, KK Leung, JA Wells Proceedings of the National Academy of Sciences 118 (4), e2018861118, 2021 | 13 | 2021 |
| Sulfur (VI) fluoride compounds and methods for the preparation thereof J Dong, KB Sharpless | 7 | 2015 |
| Soluble expression, purification, and characterization of recombinant human flotillin-2 (reggie-1) in Escherichia coli J Song, W Chen, Z Lu, X Hu, Y Ding Molecular biology reports 38, 2091-2098, 2011 | 7 | 2011 |
| Sulfur (VI) fluoride compounds and methods for the preparation thereof J Dong, KB Sharpless, JW Kelly, W Chen US Patent 10,117,840, 2018 | 6 | 2018 |
| Tree Search-Based Evolutionary Bandits for Protein Sequence Optimization J Qiu, H Yuan, J Zhang, W Chen, H Wang, M Wang Proceedings of the AAAI Conference on Artificial Intelligence 38 (13), 14686 …, 2024 | | 2024 |
| Sulfur (vi) fluoride compounds and their use in click-reaction J Dong, KB Sharpless, JW Kelly, A Baranczak, W Chen | | 2024 |
| Anti-CCR8 antibodies and uses thereof WO2022256563A1 (PCT), 2022 | | 2022 |
| T cell engager molecules and uses thereof WO2022256559A1 (PCT), 2022 | | 2022 |
