| HMGB1 activates proinflammatory signaling via TLR5 leading to allodynia N Das, V Dewan, PM Grace, RJ Gunn, R Tamura, N Tzarum, LR Watkins, ... Cell reports 17 (4), 1128-1140, 2016 | 161 | 2016 |
| VH1-69 antiviral broadly neutralizing antibodies: genetics, structures, and relevance to rational vaccine design F Chen, N Tzarum, IA Wilson, M Law Current opinion in virology 34, 149-159, 2019 | 117 | 2019 |
| N-glycolylneuraminic acid as a receptor for influenza A viruses F Broszeit, N Tzarum, X Zhu, N Nemanichvili, D Eggink, T Leenders, Z Li, ... Cell reports 27 (11), 3284-3294. e6, 2019 | 96 | 2019 |
| Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen L Kong, DE Lee, RU Kadam, T Liu, E Giang, T Nieusma, F Garces, ... Proceedings of the National Academy of Sciences 113 (45), 12768-12773, 2016 | 90 | 2016 |
| Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies N Tzarum, E Giang, L Kong, L He, J Prentoe, E Augestad, Y Hua, ... Science Advances 5 (1), eaav1882, 2019 | 86 | 2019 |
| Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis R Gopal, K Jackson, N Tzarum, L Kong, A Ettenger, J Guest, JM Pfaff, ... PLoS pathogens 13 (12), e1006735, 2017 | 71 | 2017 |
| The neutralizing face of hepatitis C virus E2 envelope glycoprotein N Tzarum, IA Wilson, M Law Frontiers in immunology 9, 1315, 2018 | 69 | 2018 |
| A human-infecting H10N8 influenza virus retains a strong preference for avian-type receptors H Zhang, RP de Vries, N Tzarum, X Zhu, W Yu, R McBride, JC Paulson, ... Cell host & microbe 17 (3), 377-384, 2015 | 60 | 2015 |
| Structure and receptor binding of the hemagglutinin from a human H6N1 influenza virus N Tzarum, RP De Vries, X Zhu, W Yu, R McBride, JC Paulson, IA Wilson Cell host & microbe 17 (3), 369-376, 2015 | 59 | 2015 |
| Proof of concept for rational design of hepatitis C virus E2 core nanoparticle vaccines L He, N Tzarum, X Lin, B Shapero, C Sou, CJ Mann, A Stano, L Zhang, ... Science advances 6 (16), eaaz6225, 2020 | 54 | 2020 |
| A single mutation in Taiwanese H6N1 influenza hemagglutinin switches binding to human‐type receptors RP de Vries, N Tzarum, W Peng, AJ Thompson, ... EMBO molecular medicine 9 (9), 1314-1325, 2017 | 53 | 2017 |
| The 150-loop restricts the host specificity of human H10N8 influenza virus N Tzarum, RP de Vries, W Peng, AJ Thompson, KM Bouwman, R McBride, ... Cell reports 19 (2), 235-245, 2017 | 40 | 2017 |
| DEF pocket in p38α facilitates substrate selectivity and mediates autophosphorylation N Tzarum, N Komornik, DB Chetrit, D Engelberg, O Livnah Journal of Biological Chemistry 288 (27), 19537-19547, 2013 | 38 | 2013 |
| Lipid molecules induce p38α activation via a novel molecular switch N Tzarum, Y Eisenberg-Domovich, JJ Gills, PA Dennis, O Livnah Journal of molecular biology 424 (5), 339-353, 2012 | 34 | 2012 |
| An alternate conformation of HCV E2 neutralizing face as an additional vaccine target N Tzarum, E Giang, RU Kadam, F Chen, K Nagy, EH Augestad, ... Science advances 6 (30), eabb5642, 2020 | 30 | 2020 |
| Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins F Chen, N Tzarum, X Lin, E Giang, R Velázquez-Moctezuma, ... Immunity 54 (4), 781-796. e4, 2021 | 28 | 2021 |
| Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors F Aleman, N Tzarum, L Kong, K Nagy, J Zhu, IA Wilson, M Law Proceedings of the National Academy of Sciences 115 (29), 7569-7574, 2018 | 20 | 2018 |
| From structural studies to HCV vaccine design I Yechezkel, M Law, N Tzarum Viruses 13 (5), 833, 2021 | 17 | 2021 |
| Active mutants of the TCR-mediated p38α alternative activation site show changes in the phosphorylation lip and DEF site formation N Tzarum, R Diskin, D Engelberg, O Livnah Journal of molecular biology 405 (5), 1154-1169, 2011 | 16 | 2011 |
| Unique structural features of influenza virus H15 hemagglutinin N Tzarum, R McBride, CM Nycholat, W Peng, JC Paulson, IA Wilson Journal of Virology 91 (12), 10.1128/jvi. 00046-17, 2017 | 15 | 2017 |
Robert P de VriesDepartment of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical ScienceVerified email at uu.nl
