Sergei Zolotukhin
Sergei Zolotukhin
Professor of Pediatrics
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Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield
S Zolotukhin, BJ Byrne, E Mason, I Zolotukhin, M Potter, K Chesnut, ...
Gene therapy 6 (6), 973-985, 1999
Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of …
C Burger, OS Gorbatyuk, MJ Velardo, CS Peden, P Williams, S Zolotukhin, ...
Molecular Therapy 10 (2), 302-317, 2004
A" humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells
S Zolotukhin, M Potter, WW Hauswirth, J Guy, N Muzyczka
Journal of virology 70 (7), 4646-4654, 1996
Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses
L Zhong, B Li, CS Mah, L Govindasamy, M Agbandje-McKenna, ...
Proceedings of the National Academy of Sciences 105 (22), 7827-7832, 2008
Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors
S Zolotukhin, M Potter, I Zolotukhin, Y Sakai, S Loiler, TJ Fraites Jr, ...
Methods 28 (2), 158-167, 2002
Efficient photoreceptor-targeted gene expression in vivo by recombinant adeno-associated virus
JG Flannery, S Zolotukhin, MI Vaquero, MM LaVail, N Muzyczka, ...
Proceedings of the National Academy of Sciences 94 (13), 6916-6921, 1997
High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors
H Petrs-Silva, A Dinculescu, Q Li, SH Min, V Chiodo, JJ Pang, L Zhong, ...
Molecular therapy 17 (3), 463-471, 2009
Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding
SR Opie, KH Warrington Jr, M Agbandje-McKenna, S Zolotukhin, ...
Journal of virology 77 (12), 6995-7006, 2003
Humanized green fluorescent protein genes and methods
S Zolotukhin, N Muzyczka, WW Hauswirth
US Patent 5,874,304, 1999
Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adeno-associated virus vectors
RL Klein, EM Meyer, AL Peel, S Zolotukhin, C Meyers, N Muzyczka, ...
Experimental neurology 150 (2), 183-194, 1998
Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters
AL Peel, S Zolotukhin, GW Schrimsher, N Muzyczka, PJ Reier
Gene therapy 4 (1), 16-24, 1997
Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats
S Shklyaev, G Aslanidi, M Tennant, V Prima, E Kohlbrenner, V Kroutov, ...
Proceedings of the National Academy of Sciences 100 (24), 14217-14222, 2003
Structure of adeno-associated virus serotype 8, a gene therapy vector
HJ Nam, MD Lane, E Padron, B Gurda, R McKenna, E Kohlbrenner, ...
Journal of virology 81 (22), 12260-12271, 2007
Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression
LI Zhong, B Li, G Jayandharan, CS Mah, L Govindasamy, ...
Virology 381 (2), 194-202, 2008
Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus
KH Warrington Jr, OS Gorbatyuk, JK Harrison, SR Opie, S Zolotukhin, ...
Journal of virology 78 (12), 6595-6609, 2004
Structural insight into the unique properties of adeno-associated virus serotype 9
MA DiMattia, HJ Nam, K Van Vliet, M Mitchell, A Bennett, BL Gurda, ...
Journal of virology 86 (12), 6947-6958, 2012
Regulation of adiponectin and leptin gene expression in white and brown adipose tissues: influence of β3-adrenergic agonists, retinoic acid, leptin and fasting
Y Zhang, M Matheny, S Zolotukhin, N Tumer, PJ Scarpace
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2002
[48] Production and purification of recombinant adeno-associated virus
WW Hauswirth, AS Lewin, S Zolotukhin, N Muzyczka
Methods in enzymology 316, 743-761, 2000
A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis
L Zhong, W Zhao, J Wu, B Li, S Zolotukhin, L Govindasamy, ...
Molecular Therapy 15 (7), 1323-1330, 2007
High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap
JE Conway, CMJ Ap Rhys, I Zolotukhin, S Zolotukhin, N Muzyczka, ...
Gene Therapy 6 (6), 986-993, 1999
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