| N-terminal and C-terminal modulation of Hsp90 produce dissimilar phenotypes Y Wang, SR McAlpine Chemical communications 51 (8), 1410-1413, 2015 | 77 | 2015 |
| Synthesis and antiproliferative activity of 4-substituted-piperazine-1-carbodithioate derivatives of 2, 4-diaminoquinazoline SL Cao, Y Han, CZ Yuan, Y Wang, ZK Xiahou, J Liao, RT Gao, BB Mao, ... European journal of medicinal chemistry 64, 401-409, 2013 | 63 | 2013 |
| Co-polymers of actin and tropomyosin account for a major fraction of the human actin cytoskeleton JCM Meiring, NS Bryce, Y Wang, MH Taft, DJ Manstein, SL Lau, J Stear, ... Current Biology, 2018 | 56 | 2018 |
| Chemically accessible hsp90 inhibitor that does not induce a heat shock response YC Koay, JR McConnell, Y Wang, SJ Kim, LK Buckton, F Mansour, ... ACS medicinal chemistry letters 5 (7), 771-776, 2014 | 51 | 2014 |
| Synthesis and cytotoxic activity of N-((2-methyl-4 (3H)-quinazolinon-6-yl) methyl) dithiocarbamates SL Cao, Y Wang, L Zhu, J Liao, YW Guo, LL Chen, HQ Liu, X Xu European journal of medicinal chemistry 45 (9), 3850-3857, 2010 | 45 | 2010 |
| Heat-shock protein 90 inhibitors: will they ever succeed as chemotherapeutics? Y Wang, SR McAlpine Future medicinal chemistry 7 (2), 87-90, 2015 | 30 | 2015 |
| Regulating the cytoprotective response in cancer cells using simultaneous inhibition of Hsp90 and Hsp70 Y Wang, SR McAlpine Organic & biomolecular chemistry 13 (7), 2108-2116, 2015 | 30 | 2015 |
| C-terminal heat shock protein 90 modulators produce desirable oncogenic properties Y Wang, SR McAlpine Organic & biomolecular chemistry 13 (16), 4627-4631, 2015 | 29 | 2015 |
| How selective are Hsp90 inhibitors for cancer cells over normal cells? Y Wang, YC Koay, SR McAlpine ChemMedChem, 353-357, 2017 | 23 | 2017 |
| Redefining the phenotype of heat shock protein 90 (Hsp90) inhibitors. Y Wang, YC Koay, SR McAlpine Chemistry-A European Journal, 2010-2013, 2017 | 19 | 2017 |
| Combining an Hsp70 inhibitor with either an N-or C-terminal Hsp90 inhibitor produces mechanistically distinct phenotypes Y Wang, SR McAlpine Organic & Biomolecular Chemistry 13 (12), 3691-3698, 2015 | 19 | 2015 |
| Blocking the heat shock response and depleting HSF-1 levels through heat shock protein 90 (hsp90) inhibition: a significant advance on current hsp90 chemotherapies YC Koay, JR McConnell, Y Wang, SR McAlpine RSC advances 5 (73), 59003-59013, 2015 | 14 | 2015 |
| Design, synthesis and anticancer mechanistic studies of linked azoles MA Islam, Y Zhang, Y Wang, SR McAlpine MedChemComm 6 (2), 300-305, 2015 | 12 | 2015 |
| The fungal natural product (1S, 3S)-austrocortirubin induces DNA damage in HCT116 cells via a mechanism unique from other DNA damaging agents Y Wang, MA Islam, RA Davis, SR McAlpine Bioorganic & medicinal chemistry letters 25 (2), 249-253, 2015 | 9 | 2015 |
| Utilizing a dimerization strategy to inhibit the dimer protein Hsp90: Synthesis and biological activity of a sansalvamide A dimer H Wahyudi, Y Wang, SR McAlpine Org Biomol Chem 12, 765-773, 2014 | 8* | 2014 |
| Novel Movable Typing for Personalized Vein‐Chips in Large Scale: Recapitulate Patient‐Specific Virchow's Triad and its Contribution to Cerebral Venous Sinus Thrombosis YC Zhao, Y Zhang, Z Wang, F Jiang, K Kyanian, SSS Aye, T Hong, ... Advanced Functional Materials 33 (23), 2214179, 2023 | 7 | 2023 |
| Targeting the C-terminus of Hsp90 as a cancer therapy J McConnell, Y Wang, S McAlpine Heat Shock Protein Inhibitors: Success Stories, 1-20, 2016 | 6 | 2016 |
| Synthesis of 1-Substituted 4 (1 H)-Quinazolinones Under Solvent-Free Conditions Y Wang, M Zhang, S Cao, H Lin, M Gao, Z Li Synthetic Communications 42 (18), 2715-2727, 2012 | 6 | 2012 |
| Synthesis and cytotoxic evaluation of quinazolin-4(3H)-one derivatives bearing thiocarbamate, thiourea or N-methyldithiocarbamate side chains. S Cao, H Xu, Y Wang, J Liao, X Li, Y Guo, Z Li, X Cui, X Xu. Medicinal Chemistry, 163-173, 2012 | 6 | 2012 |
| Evaluating dual Hsp90 and Hsp70 inhibition as a cancer therapy LK Buckton, Y Wang, JR McConnell, SR McAlpine Heat Shock Protein Inhibitors: Success Stories, 55-80, 2016 | 5 | 2016 |
