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Esam T. Abualrous
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Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation
M Wieczorek, ET Abualrous, J Sticht, M Álvaro-Benito, S Stolzenberg, ...
Frontier in Immunology, 2017
11952017
Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations
F Paul, C Wehmeyer, ET Abualrous, H Wu, MD Crabtree, J Schöneberg, ...
Nature communications 8 (1), 1095, 2017
1482017
Peptide-independent stabilization of MHC class I molecules breaches cellular quality control
Z Hein, H Uchtenhagen, ET Abualrous, SK Saini, L Janßen, ...
Journal of cell science 127 (13), 2885-2897, 2014
782014
Benchmarking refined and unrefined AlphaFold2 structures for hit discovery
Y Zhang, M Vass, D Shi, E Abualrous, JM Chambers, N Chopra, C Higgs, ...
Journal of Chemical Information and Modeling 63 (6), 1656-1667, 2023
642023
F pocket flexibility influences the tapasin dependence of two differentially disease‐associated MHC Class I proteins
ET Abualrous, S Fritzsche, Z Hein, MS Al‐Balushi, P Reinink, LH Boyle, ...
European Journal of Immunology 45 (4), 1248-1257, 2015
592015
Dynamically driven allostery in MHC proteins: Peptide-dependent tuning of class I MHC global flexibility
CM Ayres, ET Abualrous, A Bailey, C Abraham, LM Hellman, SA Corcelli, ...
Frontiers in immunology 10, 966, 2019
492019
Major histocompatibility complex (MHC) class I and class II proteins: impact of polymorphism on antigen presentation
ET Abualrous, J Sticht, C Freund
Current Opinion in Immunology 70, 95-104, 2021
482021
Not all empty MHC class I molecules are molten globules: Tryptophan fluorescence reveals a two-step mechanism of thermal denaturation
SK Saini, ET Abualrous, AS Tigan, K Covella, U Wellbrock, S Springer
Molecular immunology 54 (3-4), 386-396, 2013
472013
Quantification of HLA-DM-Dependent Major Histocompatibility Complex of Class II Immunopeptidomes by the Peptide Landscape Antigenic Epitope Alignment Utility
M Álvaro-Benito, E Morrison, ET Abualrous, B Kuropka, C Freund
Frontiers in Immunology 9, 2018
442018
The Carboxy Terminus of the Ligand Peptide Determines the Stability of the MHC Class I Molecule H-2Kb: A Combined Molecular Dynamics and Experimental Study
ET Abualrous, SK Saini, VR Ramnarayan, FT Ilca, M Zacharias, ...
PloS one 10 (8), e0135421, 2015
442015
Exchange catalysis by tapasin exploits conserved and allele-specific features of MHC-I molecules
H Lan, ET Abualrous, J Sticht, LMA Fernandez, T Werk, C Weise, ...
Nature Communications 12 (1), 4236, 2021
312021
Proline substitution independently enhances H‐2Db complex stabilization and TCR recognition of melanoma‐associated peptides
H Uchtenhagen, ET Abualrous, E Stahl, EB Allerbring, M Sluijter, ...
European journal of immunology 43 (11), 3051-3060, 2013
312013
Distinct editing functions of natural HLA-DM allotypes impact antigen presentation and CD4+ T cell activation
M Álvaro-Benito, E Morrison, F Ebner, ET Abualrous, M Urbicht, ...
Cellular & Molecular Immunology 17 (2), 133-142, 2020
262020
Geometrical characterization of T cell receptor binding modes reveals class‐specific binding to maximize access to antigen
NK Singh, ET Abualrous, CM Ayres, F Noé, R Gowthaman, BG Pierce, ...
Proteins: Structure, Function, and Bioinformatics 88 (3), 503-513, 2020
242020
Distinct mechanisms survey the structural integrity of HLA-B* 27: 05 intracellularly and at the surface
Z Hein, B Borchert, E Tolba Abualrous, S Springer
PLoS One 13 (8), e0200811, 2018
152018
Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma
E Bräunlein, G Lupoli, F Füchsl, ET Abualrous, N de Andrade Krätzig, ...
Journal for ImmunoTherapy of Cancer 9 (9), 2021
13*2021
MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange
ET Abualrous, S Stolzenberg, J Sticht, M Wieczorek, Y Roske, M Günther, ...
Nature Chemical Biology 19 (10), 1196-1204, 2023
102023
Release from endoplasmic reticulum matrix proteins controls cell surface transport of MHC class I molecules
S Fritzsche, ET Abualrous, B Borchert, F Momburg, S Springer
Traffic 16 (6), 591-603, 2015
62015
Major histocompatibility complex (MHC) class I and MHC class II proteins: Conformational plasticity in antigen presentation. Front Immunol. 2017 Mar 17; 8: 292
M Wieczorek, ET Abualrous, J Sticht, M Álvaro-Benito, S Stolzenberg, ...
52017
FBP21’s C-terminal domain remains dynamic when wrapped around the c-Sec63 Unit of Brr2 helicase
J Sticht, M Bertazzon, LM Henning, JR Licha, ET Abualrous, C Freund
Biophysical Journal 116 (3), 406-418, 2019
22019
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Articles 1–20