Martin J. Aryee
Martin J. Aryee
Assistant Professor, Pathology Dept at Massachusetts General Hospital and Harvard Medical School
Verified email at mgh.harvard.edu - Homepage
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A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the …
SS Lim, T Vos, AD Flaxman, G Danaei, K Shibuya, H Adair-Rohani, ...
The lancet 380 (9859), 2224-2260, 2012
130032012
Epigenetic memory in induced pluripotent stem cells
K Kim, A Doi, B Wen, K Ng, R Zhao, P Cahan, J Kim, MJ Aryee, H Ji, ...
Nature 467 (7313), 285-290, 2010
23272010
Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays
MJ Aryee, AE Jaffe, H Corrada-Bravo, C Ladd-Acosta, AP Feinberg, ...
Bioinformatics 30 (10), 1363-1369, 2014
23012014
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
SQ Tsai, Z Zheng, NT Nguyen, M Liebers, VV Topkar, V Thapar, ...
Nature biotechnology 33 (2), 187-197, 2015
16022015
Engineered CRISPR-Cas9 nucleases with altered PAM specificities
BP Kleinstiver, MS Prew, SQ Tsai, VV Topkar, NT Nguyen, Z Zheng, ...
Nature 523 (7561), 481-485, 2015
13232015
Differential methylation of tissue-and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
A Doi, IH Park, B Wen, P Murakami, MJ Aryee, R Irizarry, B Herb, ...
Nature genetics 41 (12), 1350-1353, 2009
12672009
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
SQ Tsai, N Wyvekens, C Khayter, JA Foden, V Thapar, D Reyon, ...
Nature biotechnology 32 (6), 569-576, 2014
10392014
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
Y Liu, MJ Aryee, L Padyukov, MD Fallin, E Hesselberg, A Runarsson, ...
Nature biotechnology 31 (2), 142-147, 2013
8582013
Comprehensive methylome map of lineage commitment from haematopoietic progenitors
H Ji, LIR Ehrlich, J Seita, P Murakami, A Doi, P Lindau, H Lee, MJ Aryee, ...
Nature 467 (7313), 338-342, 2010
6622010
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells
K Kim, R Zhao, A Doi, K Ng, J Unternaehrer, P Cahan, H Hongguang, ...
Nature biotechnology 29 (12), 1117-1119, 2011
6172011
Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements
MC Haffner, MJ Aryee, A Toubaji, DM Esopi, R Albadine, B Gurel, ...
Nature genetics 42 (8), 668-675, 2010
5722010
Global causes of diarrheal disease mortality in children< 5 years of age: a systematic review
CF Lanata, CL Fischer-Walker, AC Olascoaga, CX Torres, MJ Aryee, ...
PloS one 8 (9), e72788, 2013
5642013
Diarrhea incidence in low-and middle-income countries in 1990 and 2010: a systematic review
CLF Walker, J Perin, MJ Aryee, C Boschi-Pinto, RE Black
BMC public health 12 (1), 1-7, 2012
5632012
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
BP Kleinstiver, SQ Tsai, MS Prew, NT Nguyen, MM Welch, JM Lopez, ...
Nature biotechnology 34 (8), 869-874, 2016
4902016
CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets
SQ Tsai, NT Nguyen, J Malagon-Lopez, VV Topkar, MJ Aryee, JK Joung
Nature methods 14 (6), 607-614, 2017
4542017
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus
W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ...
PLoS genetics 6 (2), e1000841, 2010
4152010
Personalized epigenomic signatures that are stable over time and covary with body mass index
AP Feinberg, RA Irizarry, D Fradin, MJ Aryee, P Murakami, T Aspelund, ...
Science translational medicine 2 (49), 49ra67-49ra67, 2010
3542010
Integrated single-cell analysis maps the continuous regulatory landscape of human hematopoietic differentiation
JD Buenrostro, MR Corces, CA Lareau, B Wu, AN Schep, MJ Aryee, ...
Cell 173 (6), 1535-1548. e16, 2018
3512018
A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression
J Guintivano, MJ Aryee, ZA Kaminsky
Epigenetics 8 (3), 290-302, 2013
3132013
Reversible switching between epigenetic states in honeybee behavioral subcastes
BR Herb, F Wolschin, KD Hansen, MJ Aryee, B Langmead, R Irizarry, ...
Nature neuroscience 15 (10), 1371-1373, 2012
3132012
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