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Lee Denson
Lee Denson
Unknown affiliation
Verified email at cchmc.org
Title
Cited by
Cited by
Year
The treatment-naive microbiome in new-onset Crohn’s disease
D Gevers, S Kugathasan, LA Denson, Y Vázquez-Baeza, W Van Treuren, ...
Cell host & microbe 15 (3), 382-392, 2014
35002014
Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases
J Lloyd-Price, C Arze, AN Ananthakrishnan, M Schirmer, J Avila-Pacheco, ...
Nature 569 (7758), 655-662, 2019
22802019
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ...
Nature genetics 43 (3), 246-252, 2011
17622011
Single-cell analysis of Crohn’s disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy
JC Martin, C Chang, G Boschetti, R Ungaro, M Giri, JA Grout, K Gettler, ...
Cell 178 (6), 1493-1508. e20, 2019
6882019
Role of fecal calprotectin as a biomarker of intestinal inflammation in inflammatory bowel disease
MR Konikoff, LA Denson
Inflammatory bowel diseases 12 (6), 524-534, 2006
6132006
Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study
S Kugathasan, LA Denson, TD Walters, MO Kim, UM Marigorta, ...
The Lancet 389 (10080), 1710-1718, 2017
6082017
Common variants at five new loci associated with early-onset inflammatory bowel disease
M Imielinski, RN Baldassano, A Griffiths, RK Russell, V Annese, ...
Nature genetics 41 (12), 1335-1340, 2009
5852009
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
Y Haberman, TL Tickle, PJ Dexheimer, MO Kim, D Tang, R Karns, ...
The Journal of clinical investigation 124 (8), 3617-3633, 2014
5692014
The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp
LA Denson, E Sturm, W Echevarria, TL Zimmerman, M Makishima, ...
Gastroenterology 121 (1), 140-147, 2001
5622001
Dynamics of metatranscription in the inflammatory bowel disease gut microbiome
M Schirmer, EA Franzosa, J Lloyd-Price, LJ McIver, R Schwager, ...
Nature microbiology 3 (3), 337-346, 2018
5232018
Association of host genome with intestinal microbial composition in a large healthy cohort
W Turpin, O Espin-Garcia, W Xu, MS Silverberg, D Kevans, MI Smith, ...
Nature genetics 48 (11), 1413-1417, 2016
4862016
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease
S Kugathasan, RN Baldassano, JP Bradfield, PMA Sleiman, M Imielinski, ...
Nature genetics 40 (10), 1211-1215, 2008
4222008
Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease
K Wang, H Zhang, S Kugathasan, V Annese, JP Bradfield, RK Russell, ...
The American Journal of Human Genetics 84 (3), 399-405, 2009
3562009
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ...
Nature genetics 47 (2), 172-179, 2015
3552015
GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis
K Uchida, DC Beck, T Yamamoto, PY Berclaz, S Abe, MK Staudt, ...
New England Journal of Medicine 356 (6), 567-579, 2007
3322007
Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease
TD Walters, MO Kim, LA Denson, AM Griffiths, M Dubinsky, J Markowitz, ...
Gastroenterology 146 (2), 383-391, 2014
3042014
Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response
Y Haberman, R Karns, PJ Dexheimer, M Schirmer, J Somekh, I Jurickova, ...
Nature communications 10 (1), 38, 2019
2972019
Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases
YR Li, J Li, SD Zhao, JP Bradfield, FD Mentch, SM Maggadottir, C Hou, ...
Nature medicine 21 (9), 1018-1027, 2015
2812015
Compositional and temporal changes in the gut microbiome of pediatric ulcerative colitis patients are linked to disease course
M Schirmer, L Denson, H Vlamakis, EA Franzosa, S Thomas, NM Gotman, ...
Cell host & microbe 24 (4), 600-610. e4, 2018
2592018
Interleukin-1β suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation
LA Denson, KL Auld, DS Schiek, MH McClure, DJ Mangelsdorf, ...
Journal of Biological Chemistry 275 (12), 8835-8843, 2000
2462000
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