| The treatment-naive microbiome in new-onset Crohn’s disease D Gevers, S Kugathasan, LA Denson, Y Vázquez-Baeza, W Van Treuren, ... Cell host & microbe 15 (3), 382-392, 2014 | 3500 | 2014 |
| Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases J Lloyd-Price, C Arze, AN Ananthakrishnan, M Schirmer, J Avila-Pacheco, ... Nature 569 (7758), 655-662, 2019 | 2280 | 2019 |
| Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246-252, 2011 | 1762 | 2011 |
| Single-cell analysis of Crohn’s disease lesions identifies a pathogenic cellular module associated with resistance to anti-TNF therapy JC Martin, C Chang, G Boschetti, R Ungaro, M Giri, JA Grout, K Gettler, ... Cell 178 (6), 1493-1508. e20, 2019 | 688 | 2019 |
| Role of fecal calprotectin as a biomarker of intestinal inflammation in inflammatory bowel disease MR Konikoff, LA Denson Inflammatory bowel diseases 12 (6), 524-534, 2006 | 613 | 2006 |
| Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study S Kugathasan, LA Denson, TD Walters, MO Kim, UM Marigorta, ... The Lancet 389 (10080), 1710-1718, 2017 | 608 | 2017 |
| Common variants at five new loci associated with early-onset inflammatory bowel disease M Imielinski, RN Baldassano, A Griffiths, RK Russell, V Annese, ... Nature genetics 41 (12), 1335-1340, 2009 | 585 | 2009 |
| Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature Y Haberman, TL Tickle, PJ Dexheimer, MO Kim, D Tang, R Karns, ... The Journal of clinical investigation 124 (8), 3617-3633, 2014 | 569 | 2014 |
| The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp LA Denson, E Sturm, W Echevarria, TL Zimmerman, M Makishima, ... Gastroenterology 121 (1), 140-147, 2001 | 562 | 2001 |
| Dynamics of metatranscription in the inflammatory bowel disease gut microbiome M Schirmer, EA Franzosa, J Lloyd-Price, LJ McIver, R Schwager, ... Nature microbiology 3 (3), 337-346, 2018 | 523 | 2018 |
| Association of host genome with intestinal microbial composition in a large healthy cohort W Turpin, O Espin-Garcia, W Xu, MS Silverberg, D Kevans, MI Smith, ... Nature genetics 48 (11), 1413-1417, 2016 | 486 | 2016 |
| Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease S Kugathasan, RN Baldassano, JP Bradfield, PMA Sleiman, M Imielinski, ... Nature genetics 40 (10), 1211-1215, 2008 | 422 | 2008 |
| Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease K Wang, H Zhang, S Kugathasan, V Annese, JP Bradfield, RK Russell, ... The American Journal of Human Genetics 84 (3), 399-405, 2009 | 356 | 2009 |
| High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ... Nature genetics 47 (2), 172-179, 2015 | 355 | 2015 |
| GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis K Uchida, DC Beck, T Yamamoto, PY Berclaz, S Abe, MK Staudt, ... New England Journal of Medicine 356 (6), 567-579, 2007 | 332 | 2007 |
| Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease TD Walters, MO Kim, LA Denson, AM Griffiths, M Dubinsky, J Markowitz, ... Gastroenterology 146 (2), 383-391, 2014 | 304 | 2014 |
| Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response Y Haberman, R Karns, PJ Dexheimer, M Schirmer, J Somekh, I Jurickova, ... Nature communications 10 (1), 38, 2019 | 297 | 2019 |
| Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases YR Li, J Li, SD Zhao, JP Bradfield, FD Mentch, SM Maggadottir, C Hou, ... Nature medicine 21 (9), 1018-1027, 2015 | 281 | 2015 |
| Compositional and temporal changes in the gut microbiome of pediatric ulcerative colitis patients are linked to disease course M Schirmer, L Denson, H Vlamakis, EA Franzosa, S Thomas, NM Gotman, ... Cell host & microbe 24 (4), 600-610. e4, 2018 | 259 | 2018 |
| Interleukin-1β suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation LA Denson, KL Auld, DS Schiek, MH McClure, DJ Mangelsdorf, ... Journal of Biological Chemistry 275 (12), 8835-8843, 2000 | 246 | 2000 |
