| The dependence of amyloid‐β dynamics on protein force fields and water models AK Somavarapu, KP Kepp ChemPhysChem 16 (15), 3278-3289, 2015 | 109 | 2015 |
| Mycobacterium tuberculosis keto-mycolic acid and macrophage nuclear receptor TR4 modulate foamy biogenesis in granulomas: a case of a heterologous and noncanonical ligand … HK Dkhar, R Nanduri, S Mahajan, S Dave, A Saini, AK Somavarapu, ... The Journal of Immunology 193 (1), 295-305, 2014 | 66 | 2014 |
| Membrane dynamics of γ-secretase provides a molecular basis for β-amyloid binding and processing AK Somavarapu, KP Kepp ACS chemical neuroscience 8 (11), 2424-2436, 2017 | 55 | 2017 |
| The dynamic mechanism of presenilin-1 function: Sensitive gate dynamics and loop unplugging control protein access AK Somavarapu, KP Kepp Neurobiology of disease 89, 147-156, 2016 | 54 | 2016 |
| Loss of stability and hydrophobicity of presenilin 1 mutations causing Alzheimer's disease AK Somavarapu, KP Kepp Journal of neurochemistry 137 (1), 101-111, 2016 | 51 | 2016 |
| The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization A Farzadfard, JN Pedersen, G Meisl, AK Somavarapu, P Alam, L Goksøyr, ... Communications biology 5 (1), 123, 2022 | 36 | 2022 |
| Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein—Evidence for a common hot spot site at the interface and its functional … PP Nanaware, MP Ramteke, AK Somavarapu, P Venkatraman Proteins: Structure, Function, and Bioinformatics 82 (7), 1283-1300, 2014 | 33 | 2014 |
| A computer-simulated mechanism of familial Alzheimer’s disease: Mutations enhance thermal dynamics and favor looser substrate-binding to γ-secretase B Dehury, AK Somavarapu, KP Kepp Journal of Structural Biology 212 (3), 107648, 2020 | 22 | 2020 |
| Identification of a novel ATPase activity in 14-3-3 proteins–Evidence from enzyme kinetics, structure guided modeling and mutagenesis studies MP Ramteke, P Shelke, V Ramamoorthy, AK Somavarapu, AKS Gautam, ... FEBS letters 588 (1), 71-78, 2014 | 21 | 2014 |
| Molecular recipe for γ-secretase modulation from computational analysis of 60 active compounds N Tang, AK Somavarapu, KP Kepp ACS Omega 3 (12), 18078-18088, 2018 | 20 | 2018 |
| The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+–Aβ Complex AK Somavarapu, F Shen, K Teilum, J Zhang, S Mossin, PW Thulstrup, ... Chemistry–A European Journal 23 (55), 13591-13595, 2017 | 20 | 2017 |
| Direct correlation of cell toxicity to conformational ensembles of genetic Aβ Variants AK Somavarapu, KP Kepp ACS Chemical Neuroscience 6 (12), 1990-1996, 2015 | 18 | 2015 |
| ONRLDB—manually curated database of experimentally validated ligands for orphan nuclear receptors: insights into new drug discovery R Nanduri, I Bhutani, AK Somavarapu, S Mahajan, R Parkesh, P Gupta Database 2015, bav112, 2015 | 18 | 2015 |
| Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: role of an unusual and versatile PDZ-domain motif interaction and identification of putative … N Sangith, K Srinivasaraghavan, I Sahu, A Desai, S Medipally, ... FEBS Open Bio 4 (1), 571–583, 2014 | 14 | 2014 |
| Structural interrogation of phosphoproteome identified by mass spectrometry reveals allowed and disallowed regions of phosphoconformation AK Somavarapu, S Balakrishnan, AKS Gautam, DS Palmer, ... BMC structural biology 14, 1-14, 2014 | 12 | 2014 |
| The interactome of stabilized α‐synuclein oligomers and neuronal proteins F van Diggelen, SA Frank, AK Somavarapu, C Scavenius, MM Apetri, ... The FEBS journal 287 (10), 2037-2054, 2020 | 11 | 2020 |
| Cys-labeling kinetics of membrane protein GlpG: a role for specific SDS binding and micelle changes? DE Otzen, JN Pedersen, AK Somavarapu, A Clement, M Ji, EH Petersen, ... Biophysical Journal 120 (18), 4115-4128, 2021 | 5 | 2021 |
| Two Receptor Binding Strategy of SARS-CoV-2 Is Mediated by Both the N-Terminal and Receptor-Binding Spike Domain M Monti, E Milanetti, MT Frans, M Miotto, L Di Rienzo, MV Baranov, ... The Journal of Physical Chemistry B 128 (2), 451-464, 2024 | 3 | 2024 |
| Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions AK Somavarapu, G Kleijwegt, M Nagaraj, P Alam, J Nielsen, DE Otzen Chemical Science 14 (11), 3030-3047, 2023 | 1 | 2023 |
| Corrigendum to “Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of … N Sangith, K Srinivasaraghavan, I Sahu, A Desai, S Medipally, ... FEBS Open bio 5, 731, 2015 | | 2015 |
Prasanna VenkatramanProfessor, Protein Interaction lab, ACTREC, IndiaVerified email at actrec.gov.in
