| Decoding myofibroblast origins in human kidney fibrosis C Kuppe, MM Ibrahim, J Kranz, X Zhang, S Ziegler, J Perales-Patón, ... Nature 589 (7841), 281-286, 2021 | 478 | 2021 |
| Tubuloids derived from human adult kidney and urine for personalized disease modeling F Schutgens, MB Rookmaaker, T Margaritis, A Rios, C Ammerlaan, ... Nature biotechnology 37 (3), 303-313, 2019 | 380 | 2019 |
| SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 189 | 2022 |
| Advances in predictive in vitro models of drug-induced nephrotoxicity JYC Soo, J Jansen, R Masereeuw, MH Little Nature Reviews Nephrology 14 (6), 378-393, 2018 | 165 | 2018 |
| Bioengineered kidney tubules efficiently excrete uremic toxins J Jansen, M Fedecostante, MJ Wilmer, JG Peters, UM Kreuser, ... Scientific reports 6 (1), 26715, 2016 | 146 | 2016 |
| Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration HAM Mutsaers, MJG Wilmer, D Reijnders, J Jansen, PHH van den Broek, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (1), 142-150, 2013 | 128 | 2013 |
| Human proximal tubule epithelial cells cultured on hollow fibers: living membranes that actively transport organic cations J Jansen, IE De Napoli, M Fedecostante, CMS Schophuizen, ... Scientific reports 5 (1), 16702, 2015 | 118 | 2015 |
| A morphological and functional comparison of proximal tubule cell lines established from human urine and kidney tissue J Jansen, CMS Schophuizen, MJ Wilmer, SHM Lahham, HAM Mutsaers, ... Experimental cell research 323 (1), 87-99, 2014 | 117 | 2014 |
| The influence of dietary protein intake on mammalian tryptophan and phenolic metabolites R Poesen, HAM Mutsaers, K Windey, PH Van Den Broek, V Verweij, ... PLoS One 10 (10), e0140820, 2015 | 104 | 2015 |
| Genetic disorders in complement (regulating) genes in patients with atypical haemolytic uraemic syndrome (aHUS) D Westra, E Volokhina, E Van der Heijden, A Vos, M Huigen, J Jansen, ... Nephrology Dialysis Transplantation 25 (7), 2195-2202, 2010 | 103 | 2010 |
| Remote sensing and signaling in kidney proximal tubules stimulates gut microbiome-derived organic anion secretion J Jansen, K Jansen, E Neven, R Poesen, A Othman, A van Mil, J Sluijter, ... Proceedings of the National Academy of Sciences 116 (32), 16105-16110, 2019 | 89 | 2019 |
| Kidney organoids and tubuloids FA Yousef Yengej, J Jansen, MB Rookmaaker, MC Verhaar, H Clevers Cells 9 (6), 1326, 2020 | 86 | 2020 |
| From portable dialysis to a bioengineered kidney MK van Gelder, SM Mihaila, J Jansen, M Wester, MC Verhaar, JA Joles, ... Expert review of medical devices 15 (5), 323-336, 2018 | 71 | 2018 |
| Development of a living membrane comprising a functional human renal proximal tubule cell monolayer on polyethersulfone polymeric membrane CMS Schophuizen, IE De Napoli, J Jansen, S Teixeira, MJ Wilmer, ... Acta biomaterialia 14, 22-32, 2015 | 69 | 2015 |
| Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter CMS Schophuizen, MJ Wilmer, J Jansen, L Gustavsson, C Hilgendorf, ... Pflügers Archiv-European Journal of Physiology 465, 1701-1714, 2013 | 67 | 2013 |
| Biotechnological challenges of bioartificial kidney engineering J Jansen, M Fedecostante, MJ Wilmer, LP Van den Heuvel, ... Biotechnology advances 32 (7), 1317-1327, 2014 | 65 | 2014 |
| Upscaling of a living membrane for bioartificial kidney device NV Chevtchik, M Fedecostante, J Jansen, M Mihajlovic, M Wilmer, M Rüth, ... European journal of pharmacology 790, 28-35, 2016 | 59 | 2016 |
| Disposition and clinical implications of protein-bound uremic toxins J Jansen, J Jankowski, PR Gajjala, JFM Wetzels, R Masereeuw Clinical science 131 (14), 1631-1647, 2017 | 52 | 2017 |
| Restoration of complex V deficiency caused by a novel deletion in the human TMEM70 gene normalizes mitochondrial morphology AI Jonckheere, M Huigsloot, M Lammens, J Jansen, LP van den Heuvel, ... Mitochondrion 11 (6), 954-963, 2011 | 51 | 2011 |
| Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 45 | 2023 |
