Florence Wagner
Florence Wagner
Broad Institute
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Hdac3 is essential for the maintenance of chromatin structure and genome stability
S Bhaskara, SK Knutson, G Jiang, MB Chandrasekharan, AJ Wilson, ...
Cancer cell 18 (5), 436-447, 2010
Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories
J Gräff, NF Joseph, ME Horn, A Samiei, J Meng, J Seo, D Rei, AW Bero, ...
Cell 156 (1-2), 261-276, 2014
Progress in understanding and treating SCN2A-mediated disorders
SJ Sanders, AJ Campbell, JR Cottrell, RS Moller, FF Wagner, ...
Trends in neurosciences 41 (7), 442-456, 2018
Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif
FF Wagner, DE Olson, JP Gale, T Kaya, M Weïwer, N Aidoud, M Thomas, ...
Journal of medicinal chemistry 56 (4), 1772-1776, 2013
Characterization of Plant-Derived Saponin Natural Products against Candida albicans
JJ Coleman, I Okoli, GP Tegos, EB Holson, FF Wagner, MR Hamblin, ...
ACS chemical biology 5 (3), 321-332, 2010
A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests
FA Schroeder, MC Lewis, DM Fass, FF Wagner, YL Zhang, KM Hennig, ...
PloS one 8 (8), e71323, 2013
Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay
I Okoli, JJ Coleman, E Tempakakis, WF An, E Holson, F Wagner, ...
PloS one 4 (9), e7025, 2009
Small molecule inhibitors of zinc-dependent histone deacetylases
FF Wagner, M Weїwer, MC Lewis, EB Holson
Neurotherapeutics 10, 589-604, 2013
Discovery of the first histone deacetylase 6/8 dual inhibitors
DE Olson, FF Wagner, T Kaya, JP Gale, N Aidoud, EL Davoine, F Lazzaro, ...
Journal of medicinal chemistry 56 (11), 4816-4820, 2013
AKT kinase activity is required for lithium to modulate mood-related behaviors in mice
JQ Pan, MC Lewis, JK Ketterman, EL Clore, M Riley, KR Richards, ...
Neuropsychopharmacology 36 (7), 1397-1411, 2011
Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries
JT Lowe, MD Lee IV, LB Akella, E Davoine, EJ Donckele, L Durak, ...
The Journal of organic chemistry 77 (17), 7187-7211, 2012
Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy
BS Ferguson, BC Harrison, MY Jeong, BG Reid, MF Wempe, FF Wagner, ...
Proceedings of the National Academy of Sciences 110 (24), 9806-9811, 2013
Small molecule targets TMED9 and promotes lysosomal degradation to reverse proteinopathy
M Dvela-Levitt, M Kost-Alimova, M Emani, E Kohnert, R Thompson, ...
Cell 178 (3), 521-535. e23, 2019
Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers
FF Wagner, YL Zhang, DM Fass, N Joseph, JP Gale, M Weïwer, ...
Chemical science 6 (1), 804-815, 2015
Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis
DHC Chou, EB Holson, FF Wagner, AJ Tang, RL Maglathlin, TA Lewis, ...
Chemistry & biology 19 (6), 669-673, 2012
An unbiased approach to identify endogenous substrates of “histone” deacetylase 8
DE Olson, ND Udeshi, NA Wolfson, CA Pitcairn, ED Sullivan, JD Jaffe, ...
ACS chemical biology 9 (10), 2210-2216, 2014
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation
SM Frumm, ZP Fan, KN Ross, JR Duvall, S Gupta, L VerPlank, BC Suh, ...
Chemistry & biology 20 (5), 713-725, 2013
Selective HDAC inhibition for the disruption of latent HIV-1 infection
KM Barton, NM Archin, KS Keedy, AS Espeseth, Y Zhang, J Gale, ...
PloS one 9 (8), e102684, 2014
In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs
C Wang, FA Schroeder, HY Wey, R Borra, FF Wagner, S Reis, SW Kim, ...
Journal of medicinal chemistry 57 (19), 7999-8009, 2014
An isochemogenic set of inhibitors to define the therapeutic potential of histone deacetylases in β-cell protection
FF Wagner, M Lundh, T Kaya, P McCarren, YL Zhang, S Chattopadhyay, ...
ACS chemical biology 11 (2), 363-374, 2016
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