| Hdac3 is essential for the maintenance of chromatin structure and genome stability S Bhaskara, SK Knutson, G Jiang, MB Chandrasekharan, AJ Wilson, ... Cancer cell 18 (5), 436-447, 2010 | 360 | 2010 |
| Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories J Gräff, NF Joseph, ME Horn, A Samiei, J Meng, J Seo, D Rei, AW Bero, ... Cell 156 (1-2), 261-276, 2014 | 327 | 2014 |
| Progress in understanding and treating SCN2A-mediated disorders SJ Sanders, AJ Campbell, JR Cottrell, RS Moller, FF Wagner, ... Trends in neurosciences 41 (7), 442-456, 2018 | 174 | 2018 |
| Potent and selective inhibition of histone deacetylase 6 (HDAC6) does not require a surface-binding motif FF Wagner, DE Olson, JP Gale, T Kaya, M Weïwer, N Aidoud, M Thomas, ... Journal of medicinal chemistry 56 (4), 1772-1776, 2013 | 154 | 2013 |
| Characterization of Plant-Derived Saponin Natural Products against Candida albicans JJ Coleman, I Okoli, GP Tegos, EB Holson, FF Wagner, MR Hamblin, ... ACS chemical biology 5 (3), 321-332, 2010 | 148 | 2010 |
| A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests FA Schroeder, MC Lewis, DM Fass, FF Wagner, YL Zhang, KM Hennig, ... PloS one 8 (8), e71323, 2013 | 142 | 2013 |
| Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay I Okoli, JJ Coleman, E Tempakakis, WF An, E Holson, F Wagner, ... PloS one 4 (9), e7025, 2009 | 134 | 2009 |
| Small molecule inhibitors of zinc-dependent histone deacetylases FF Wagner, M Weїwer, MC Lewis, EB Holson Neurotherapeutics 10, 589-604, 2013 | 128 | 2013 |
| Discovery of the first histone deacetylase 6/8 dual inhibitors DE Olson, FF Wagner, T Kaya, JP Gale, N Aidoud, EL Davoine, F Lazzaro, ... Journal of medicinal chemistry 56 (11), 4816-4820, 2013 | 125 | 2013 |
| AKT kinase activity is required for lithium to modulate mood-related behaviors in mice JQ Pan, MC Lewis, JK Ketterman, EL Clore, M Riley, KR Richards, ... Neuropsychopharmacology 36 (7), 1397-1411, 2011 | 115 | 2011 |
| Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries JT Lowe, MD Lee IV, LB Akella, E Davoine, EJ Donckele, L Durak, ... The Journal of organic chemistry 77 (17), 7187-7211, 2012 | 109 | 2012 |
| Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy BS Ferguson, BC Harrison, MY Jeong, BG Reid, MF Wempe, FF Wagner, ... Proceedings of the National Academy of Sciences 110 (24), 9806-9811, 2013 | 100 | 2013 |
| Small molecule targets TMED9 and promotes lysosomal degradation to reverse proteinopathy M Dvela-Levitt, M Kost-Alimova, M Emani, E Kohnert, R Thompson, ... Cell 178 (3), 521-535. e23, 2019 | 98 | 2019 |
| Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers FF Wagner, YL Zhang, DM Fass, N Joseph, JP Gale, M Weïwer, ... Chemical science 6 (1), 804-815, 2015 | 96 | 2015 |
| Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis DHC Chou, EB Holson, FF Wagner, AJ Tang, RL Maglathlin, TA Lewis, ... Chemistry & biology 19 (6), 669-673, 2012 | 95 | 2012 |
| An unbiased approach to identify endogenous substrates of “histone” deacetylase 8 DE Olson, ND Udeshi, NA Wolfson, CA Pitcairn, ED Sullivan, JD Jaffe, ... ACS chemical biology 9 (10), 2210-2216, 2014 | 93 | 2014 |
| Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation SM Frumm, ZP Fan, KN Ross, JR Duvall, S Gupta, L VerPlank, BC Suh, ... Chemistry & biology 20 (5), 713-725, 2013 | 90 | 2013 |
| Selective HDAC inhibition for the disruption of latent HIV-1 infection KM Barton, NM Archin, KS Keedy, AS Espeseth, Y Zhang, J Gale, ... PloS one 9 (8), e102684, 2014 | 83 | 2014 |
| In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs C Wang, FA Schroeder, HY Wey, R Borra, FF Wagner, S Reis, SW Kim, ... Journal of medicinal chemistry 57 (19), 7999-8009, 2014 | 81 | 2014 |
| An isochemogenic set of inhibitors to define the therapeutic potential of histone deacetylases in β-cell protection FF Wagner, M Lundh, T Kaya, P McCarren, YL Zhang, S Chattopadhyay, ... ACS chemical biology 11 (2), 363-374, 2016 | 71 | 2016 |
