Mihály Kovács
Mihály Kovács
Eötvös Loránd University, Department of Biochemistry, Budapest, Hungary
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Mechanism of blebbistatin inhibition of myosin II
M Kovács, J Tóth, C Hetényi, A Málnási-Csizmadia, JR Sellers
Journal of Biological Chemistry 279 (34), 35557-35563, 2004
Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform
M Kovács, F Wang, A Hu, Y Zhang, JR Sellers
Journal of Biological Chemistry 278 (40), 38132-38140, 2003
Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance
F Wang, M Kovács, A Hu, J Limouze, EV Harvey, JR Sellers
Journal of Biological Chemistry 278 (30), 27439-27448, 2003
Load-dependent mechanism of nonmuscle myosin 2
M Kovács, K Thirumurugan, PJ Knight, JR Sellers
Proceedings of the National Academy of Sciences 104 (24), 9994-9999, 2007
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis
X Ma, M Kovács, MA Conti, A Wang, Y Zhang, JR Sellers, RS Adelstein
Proceedings of the National Academy of Sciences 109 (12), 4509-4514, 2012
Kinetic resolution of a conformational transition and the ATP hydrolysis step using relaxation methods with a Dictyostelium myosin II mutant containing a single tryptophan residue
A Málnási-Csizmadia, DS Pearson, M Kovács, RJ Woolley, MA Geeves, ...
Biochemistry 40 (42), 12727-12737, 2001
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C
KY Kim, M Kovács, S Kawamoto, JR Sellers, RS Adelstein
Journal of Biological Chemistry 280 (24), 22769-22775, 2005
Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor
Y Yang, S Gourinath, M Kovács, L Nyitray, R Reutzel, DM Himmel, ...
Structure 15 (5), 553-564, 2007
Myosin cleft movement and its coupling to actomyosin dissociation
PB Conibear, CR Bagshaw, PG Fajer, M Kovács, A Málnási-Csizmadia
Nature Structural & Molecular Biology 10 (10), 831-835, 2003
Targeting myosin by blebbistatin derivatives: optimization and pharmacological potential
AÁ Rauscher, M Gyimesi, M Kovács, A Málnási-Csizmadia
Trends in biochemical sciences 43 (9), 700-713, 2018
Phase separation by ssDNA binding protein controlled via protein− protein and protein− DNA interactions
GM Harami, ZJ Kovács, R Pancsa, J Pálinkás, V Baráth, K Tárnok, ...
Proceedings of the National Academy of Sciences 117 (42), 26206-26217, 2020
From keys to bulldozers: expanding roles for winged helix domains in nucleic-acid-binding proteins
GM Harami, M Gyimesi, M Kovács
Trends in biochemical sciences 38 (7), 364-371, 2013
Kinetic mechanism of human dUTPase, an essential nucleotide pyrophosphatase enzyme
J Tóth, B Varga, M Kovács, A Málnási-Csizmadia, BG Vértessy
Journal of Biological Chemistry 282 (46), 33572-33582, 2007
A single mutation in a tunnel to the active site changes the mechanism and kinetics of product release in haloalkane dehalogenase LinB
L Biedermannová, Z Prokop, A Gora, E Chovancová, M Kovács, ...
Journal of Biological Chemistry 287 (34), 29062-29074, 2012
Emerging complex pathways of the actomyosin powerstroke
A Málnási-Csizmadia, M Kovács
Trends in biochemical sciences 35 (12), 684-690, 2010
Dimerized Drosophila myosin VIIa: a processive motor
Y Yang, M Kovács, T Sakamoto, F Zhang, DP Kiehart, JR Sellers
Proceedings of the National Academy of Sciences 103 (15), 5746-5751, 2006
Myosin V from Drosophila reveals diversity of motor mechanisms within the myosin V family
J Tóth, M Kovács, F Wang, L Nyitray, JR Sellers
Journal of Biological Chemistry 280 (34), 30594-30603, 2005
The Dynamics of the Relay Loop Tryptophan Residue in theDictyostelium Myosin Motor Domain and the Origin of Spectroscopic Signals
A Málnási-Csizmadia, M Kovács, RJ Woolley, SW Botchway, ...
Journal of Biological Chemistry 276 (22), 19483-19490, 2001
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke
B Takács, N Billington, M Gyimesi, B Kintses, A Málnási-Csizmadia, ...
Proceedings of the National Academy of Sciences 107 (15), 6799-6804, 2010
Human myosin Vc is a low duty ratio, nonprocessive molecular motor
Y Takagi, Y Yang, I Fujiwara, D Jacobs, RE Cheney, JR Sellers, M Kovacs
Journal of Biological Chemistry 283 (13), 8527-8537, 2008
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