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Costin Leu
Costin Leu
Research staff at the Cleveland Clinic
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ...
Science 360 (6395), eaap8757, 2018
10762018
15q13. 3 microdeletions increase risk of idiopathic generalized epilepsy
I Helbig, HC Mefford, AJ Sharp, M Guipponi, M Fichera, A Franke, ...
Nature genetics 41 (2), 160-162, 2009
6342009
Recurrent microdeletions at 15q11. 2 and 16p13. 11 predispose to idiopathic generalized epilepsies
CGF de Kovel, H Trucks, I Helbig, HC Mefford, C Baker, C Leu, C Kluck, ...
Brain 133 (1), 23-32, 2010
4662010
Familial and sporadic 15q13. 3 microdeletions in idiopathic generalized epilepsy: precedent for disorders with complex inheritance
LM Dibbens, S Mullen, I Helbig, HC Mefford, MA Bayly, S Bellows, C Leu, ...
Human molecular genetics 18 (19), 3626-3631, 2009
2432009
Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A
D Kasperavičiūtė, CB Catarino, M Matarin, C Leu, J Novy, A Tostevin, ...
Brain 136 (10), 3140-3150, 2013
1742013
Ultra-rare genetic variation in the epilepsies: a whole-exome sequencing study of 17,606 individuals
YCA Feng, DP Howrigan, LE Abbott, K Tashman, F Cerrato, T Singh, ...
The American Journal of Human Genetics 105 (2), 267-282, 2019
1522019
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
TILAE Consortium
The Lancet. Neurology 13 (9), 893, 2014
1462014
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
Nature communications 9 (1), 5269, 2018
1412018
Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16. 1, 2q22. 3 and 17q21. 32
Epicure Consortium, EMINet Consortium, M Steffens, C Leu, AK Ruppert, ...
Human molecular genetics 21 (24), 5359-5372, 2012
1392012
CHD2 variants are a risk factor for photosensitivity in epilepsy
EC Galizia, CT Myers, C Leu, CGF De Kovel, T Afrikanova, ...
Brain 138 (5), 1198-1208, 2015
1192015
GLUT1 mutations are a rare cause of familial idiopathic generalized epilepsy
P Striano, YG Weber, MR Toliat, J Schubert, C Leu, R Chaimana, ...
Neurology 78 (8), 557-562, 2012
1132012
Pitfalls in genetic testing: the story of missed SCN1A mutations
T Djémié, S Weckhuysen, S von Spiczak, GL Carvill, J Jaehn, ...
Molecular genetics & genomic medicine 4 (4), 457-464, 2016
732016
Dysfunction of NaV1. 4, a skeletal muscle voltage-gated sodium channel, in sudden infant death syndrome: a case-control study
R Männikkö, L Wong, DJ Tester, MG Thor, R Sud, DM Kullmann, ...
The Lancet 391 (10129), 1483-1492, 2018
712018
Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study
P May, S Girard, M Harrer, DR Bobbili, J Schubert, S Wolking, F Becker, ...
The Lancet Neurology 17 (8), 699-708, 2018
682018
Carbamazepine‐and oxcarbazepine‐induced hyponatremia in people with epilepsy
B Berghuis, J van der Palen, GJ de Haan, D Lindhout, BPC Koeleman, ...
Epilepsia 58 (7), 1227-1233, 2017
672017
Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy
D Lal, H Trucks, RS Mřller, H Hjalgrim, BPC Koeleman, CGF de Kovel, ...
Epilepsia 54 (2), 265-271, 2013
662013
Exon‐disrupting deletions of NRXN1 in idiopathic generalized epilepsy
RS Mřller, YG Weber, LL Klitten, H Trucks, H Muhle, WS Kunz, ...
Epilepsia 54 (2), 256-264, 2013
652013
Polygenic burden in focal and generalized epilepsies
C Leu, R Stevelink, AW Smith, SB Goleva, M Kanai, L Ferguson, ...
Brain 142 (11), 3473-3481, 2019
632019
Predicting functional effects of missense variants in voltage-gated sodium and calcium channels
HO Heyne, D Baez-Nieto, S Iqbal, DS Palmer, A Brunklaus, P May, ...
Science translational medicine 12 (556), eaay6848, 2020
572020
Genome-wide polygenic burden of rare deleterious variants in sudden unexpected death in epilepsy
C Leu, S Balestrini, B Maher, L Hernández-Hernández, P Gormley, ...
EBioMedicine 2 (9), 1063-1070, 2015
542015
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