Epigenetic modifications and head and neck cancer: implications for tumor progression and resistance to therapy RM Castilho, CH Squarize, LO Almeida International journal of molecular sciences 18 (7), 1506, 2017 | 173 | 2017 |
Epigenetic Modifications of Histones in Periodontal Disease CRM Martins MD, Jiao Y, Larsson L, Almeida LO, Garaicoa-Pazmino C, Le JM ... J Dent Res, 1-8, 2015 | 143* | 2015 |
NFκB mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC) LO Almeida, AC Abrahao, LK Rosselli-Murai, FS Giudice, C Zagni, ... FEBS open bio 4, 96-104, 2014 | 136 | 2014 |
Periostin responds to mechanical stress and tension by activating the MTOR signaling pathway LK Rosselli-Murai, LO Almeida, C Zagni, P Galindo-Moreno, ... PloS one 8 (12), e83580, 2013 | 63 | 2013 |
Unlocking the chromatin of adenoid cystic carcinomas using HDAC inhibitors sensitize cancer stem cells to cisplatin and induces tumor senescence LO Almeida, DM Guimarães, MD Martins, MAT Martins, KA Warner, ... Stem cell research 21, 94-105, 2017 | 59 | 2017 |
PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells CS Matsumoto, LO Almeida, DM Guimarães, MD Martins, P Papagerakis, ... Oncotarget 7 (27), 42393, 2016 | 57 | 2016 |
Cancer stem cells: powerful targets to improve current anticancer therapeutics RL Bighetti-Trevisan, LO Sousa, RM Castilho, LO Almeida Stem cells international 2019, 2019 | 51 | 2019 |
SET protein accumulates in HNSCC and contributes to cell survival: antioxidant defense, Akt phosphorylation and AVOs acidification AM Leopoldino, CH Squarize, CB Garcia, LO Almeida, CR Pestana, ... Oral oncology 48 (11), 1106-1113, 2012 | 51 | 2012 |
Accumulation of the SET protein in HEK293T cells and mild oxidative stress: cell survival or death signaling AM Leopoldino, CH Squarize, CB Garcia, LO Almeida, CR Pestana, ... Molecular and cellular biochemistry 363, 65-74, 2012 | 49 | 2012 |
Polymorphisms and DNA methylation of gene TP53 associated with extra-axial brain tumors LO Almeida, AC Custódio, GR Pinto, MJ Santos, JR Almeida, CA Clara, ... Genet Mol Res 8 (1), 8-18, 2009 | 47 | 2009 |
Sensitizing mucoepidermoid carcinomas to chemotherapy by targeted disruption of cancer stem cells DM Guimarães, LO Almeida, MD Martins, KA Warner, ARS Silva, ... Oncotarget 7 (27), 42447, 2016 | 43 | 2016 |
Profiling the behavior of distinct populations of head and neck cancer stem cells LO Almeida, DM Guimarães, CH Squarize, RM Castilho Cancers 8 (1), 7, 2016 | 36 | 2016 |
Targeting histone deacetylase and NFκB signaling as a novel therapy for Mucoepidermoid Carcinomas VP Wagner, MD Martins, MAT Martins, LO Almeida, KA Warner, JE Nör, ... Scientific Reports 8 (1), 2065, 2018 | 31 | 2018 |
Epigenetic modifications and accumulation of DNA double-strand breaks in oral lichen planus lesions presenting poor response to therapy CS Dillenburg, MAT Martins, LO Almeida, L Meurer, CH Squarize, ... Medicine 94 (30), e997, 2015 | 31 | 2015 |
Laser phototherapy triggers the production of reactive oxygen species in oral epithelial cells without inducing DNA damage CS Dillenburg, LO Almeida, MD Martins, CH Squarize, RM Castilho Journal of biomedical optics 19 (4), 048002-048002, 2014 | 31 | 2014 |
PTEN mediates activation of core clock protein BMAL1 and accumulation of epidermal stem cells C Zagni, LO Almeida, T Balan, MT Martins, LK Rosselli-Murai, ... Stem cell reports 9 (1), 304-314, 2017 | 29 | 2017 |
SET overexpression decreases cell detoxification efficiency: ALDH 2 and GSTP 1 are downregulated, DDR is impaired and DNA damage accumulates LO Almeida, RN Goto, CR Pestana, SA Uyemura, S Gutkind, C Curti, ... The FEBS Journal 279 (24), 4615-4628, 2012 | 29 | 2012 |
Variation in DNA repair gene XRCC3 affects susceptibility to astrocytomas and glioblastomas AC Custodio, LO Almeida, GR Pinto, MJ Santos, JR Almeida, CA Clara, ... Genet Mol Res 11 (1), 332-9, 2012 | 29 | 2012 |
Analysis of the polymorphisms XRCC1Arg194Trp and XRCC1Arg399Gln in gliomas AC Custódio, LO Almeida, GR Pinto, MJ Santos, JR Almeida, CA Clara, ... Genet Mol Res 10 (2), 1120-1129, 2011 | 29 | 2011 |
SET oncoprotein accumulation regulates transcription through DNA demethylation and histone hypoacetylation LO Almeida, MPC Neto, LO Sousa, MA Tannous, C Curti, AM Leopoldino Oncotarget 8 (16), 26802, 2017 | 26 | 2017 |