| Synthesis and evaluation of antifungal properties of a series of the novel 2-amino-5-oxo-4-phenyl-5, 6, 7, 8-tetrahydroquinoline-3-carbonitrile and its analogues AR Gholap, KS Toti, F Shirazi, R Kumari, MK Bhat, MV Deshpande, ... Bioorganic & medicinal chemistry 15 (21), 6705-6715, 2007 | 181 | 2007 |
| Efficient synthesis of antifungal pyrimidines via palladium catalyzed Suzuki/Sonogashira cross-coupling reaction from Biginelli 3, 4-dihydropyrimidin-2 (1H)-ones AR Gholap, KS Toti, F Shirazi, MV Deshpande, KV Srinivasan Tetrahedron 64 (44), 10214-10223, 2008 | 117 | 2008 |
| South (S)-and North (N)-methanocarba-7-deazaadenosine analogues as inhibitors of human adenosine kinase KS Toti, D Osborne, A Ciancetta, D Boison, KA Jacobson Journal of medicinal chemistry 59 (14), 6860-6877, 2016 | 42 | 2016 |
| Lack of adipocyte purinergic P2Y6 receptor greatly improves whole body glucose homeostasis S Jain, SP Pydi, KS Toti, B Robaye, M Idzko, O Gavrilova, J Wess, ... Proceedings of the National Academy of Sciences 117 (48), 30763-30774, 2020 | 39 | 2020 |
| Synthesis of an apionucleoside family and discovery of a prodrug with anti-HIV activity KS Toti, M Derudas, F Pertusati, D Sinnaeve, F Van den Broeck, ... The Journal of Organic Chemistry 79 (11), 5097-5112, 2014 | 38 | 2014 |
| Nucleosides with transposed base or 4′-hydroxymethyl moieties and their corresponding oligonucleotides K Toti, M Renders, E Groaz, P Herdewijn, S Van Calenbergh Chemical Reviews 115 (24), 13484-13525, 2015 | 24 | 2015 |
| Polypharmacology of conformationally locked methanocarba nucleosides KA Jacobson, DK Tosh, KS Toti, A Ciancetta Drug Discovery Today 22 (12), 1782-1791, 2017 | 19 | 2017 |
| Pyrimidine nucleotides containing a (S)-methanocarba ring as P2Y 6 receptor agonists KS Toti, S Jain, A Ciancetta, R Balasubramanian, S Chakraborty, ... MedChemComm 8 (10), 1897-1908, 2017 | 18 | 2017 |
| Synthesis and evaluation of 5′-modified thymidines and 5-hydroxymethyl-2′-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors KS Toti, F Verbeke, MDP Risseeuw, V Frecer, H Munier-Lehmann, ... Bioorganic & medicinal chemistry 21 (1), 257-268, 2013 | 18 | 2013 |
| Identification of a new heterocyclic scaffold for inhibitors of the polo-box domain of polo-like kinase 1 CN Alverez, JE Park, KS Toti, Y Xia, KW Krausz, G Rai, JK Bang, ... Journal of medicinal chemistry 63 (22), 14087-14117, 2020 | 16 | 2020 |
| Adenosine Kinase expression determines DNA methylation in cancer cell lines AE Wahba, D Fedele, H Gebril, E AlHarfoush, KS Toti, KA Jacobson, ... ACS pharmacology & translational science 4 (2), 680-686, 2021 | 13 | 2021 |
| Allosteric Antagonism of the A2A Adenosine Receptor by a Series of Bitopic Ligands ZG Gao, KS Toti, R Campbell, RR Suresh, H Yang, KA Jacobson Cells 9 (5), 1200, 2020 | 12 | 2020 |
| Synthesis and antiviral evaluation of α-l-2′-deoxythreofuranosyl nucleosides KS Toti, M Derudas, C McGuigan, J Balzarini, S Van Calenbergh European journal of medicinal chemistry 46 (9), 3704-3713, 2011 | 10 | 2011 |
| Structure-activity relationships of pyrimidine nucleotides containing a 5′-α, β-methylene diphosphonate at the P2Y6 receptor P Oliva, M Scortichini, C Dobelmann, S Jain, V Gopinatth, KS Toti, ... Bioorganic & medicinal chemistry letters 45, 128137, 2021 | 8 | 2021 |
| A Practical Method for Regioselective 5′-O-tert-Butyldimethylsilyl Deprotection of Persilylated Nucleosides by Methanolic Phosphomolybdic Acid HS Huang, R Kong, XA Zheng, WJ Chen, SB Han, DY Zeng, SS Gong, ... Synlett 29 (18), 2437-2443, 2018 | 8 | 2018 |
| A2A Adenosine Receptor: Structures, Modeling, and Medicinal Chemistry S Baraldi, PG Baraldi, P Oliva, KS Toti, A Ciancetta, KA Jacobson The Adenosine Receptors, 91-136, 2018 | 8 | 2018 |
| Synthesis and evaluation of N6-substituted apioadenosines as potential adenosine A3 receptor modulators KS Toti, SM Moss, S Paoletta, ZG Gao, KA Jacobson, S Van Calenbergh Bioorganic & medicinal chemistry 22 (15), 4257-4268, 2014 | 7 | 2014 |
| Structure activity relationship of novel antiviral nucleosides against Enterovirus A71 DK Tosh, KS Toti, BL Hurst, JG Julander, KA Jacobson Bioorganic & Medicinal Chemistry Letters 30 (23), 127599, 2020 | 6 | 2020 |
| Prevention and rescue of cardiac dysfunction by methanocarba adenosine monophosphonate derivatives JB Shen, KS Toti, S Chakraborty, TS Kumar, C Cronin, BT Liang, ... Purinergic Signalling 16, 61-72, 2020 | 6 | 2020 |
| Novel alendronate-CGS21680 conjugate reduces bone resorption and induces new bone formation in post-menopausal osteoporosis and inflammatory osteolysis mouse models A Larrañaga-Vera, KS Toti, JS Flatow, AJ Haraczy, E Warnick, H Rao, ... Arthritis Research & Therapy 24 (1), 265, 2022 | 5 | 2022 |
