| Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells J Zuin, JR Dixon, MIJA van der Reijden, Z Ye, P Kolovos, RWW Brouwer, ... Proceedings of the National Academy of Sciences 111 (3), 996-1001, 2014 | 919 | 2014 |
| eRNAs are required for p53-dependent enhancer activity and gene transcription CA Melo, J Drost, PJ Wijchers, H van de Werken, E de Wit, JAFO Vrielink, ... Molecular cell 49 (3), 524-535, 2013 | 585 | 2013 |
| Robust 4C-seq data analysis to screen for regulatory DNA interactions HJG van de Werken, G Landan, SJB Holwerda, M Hoichman, P Klous, ... Nature methods 9 (10), 969-972, 2012 | 452 | 2012 |
| The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA E Splinter, E de Wit, EP Nora, P Klous, HJG van de Werken, Y Zhu, ... Genes and Development 25 (13), 1371-1383, 2011 | 382 | 2011 |
| The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies L Angus, M Smid, SM Wilting, J van Riet, A Van Hoeck, L Nguyen, ... Nature genetics 51 (10), 1450-1458, 2019 | 306 | 2019 |
| Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: from fixation to computation E Splinter, E de Wit, HJG van de Werken, P Klous, W de Laat Methods 58 (3), 221-230, 2012 | 264 | 2012 |
| 4C Technology: Protocols and Data Analysis HJG van de Werken, PJP de Vree, E Splinter, SJB Holwerda, P Klous, ... Methods in Enzymology 513 (Nucleosomes, Histones & Chromatin), 89, 2012 | 261 | 2012 |
| A common genetic variant within SCN10A modulates cardiac SCN5A expression M Van Den Boogaard, S Smemo, O Burnicka-Turek, DE Arnolds, ... Journal of clinical investigation 124 (4), 1844-1852, 2014 | 220 | 2014 |
| Paneth cells respond to inflammation and contribute to tissue regeneration by acquiring stem-like features through SCF/c-Kit signaling M Schmitt, M Schewe, A Sacchetti, D Feijtel, WS van de Geer, ... Cell reports 24 (9), 2312-2328. e7, 2018 | 219 | 2018 |
| Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor saccharolyticus HJG van de Werken, MRA Verhaart, AL VanFossen, K Willquist, DL Lewis, ... Applied and environmental microbiology 74 (21), 6720-6729, 2008 | 214 | 2008 |
| The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact LF van Dessel, J van Riet, M Smits, Y Zhu, P Hamberg, ... Nature communications 10 (1), 1-13, 2019 | 193 | 2019 |
| The lncRNA MIR31HG regulates p16INK4A expression to modulate senescence M Montes, MM Nielsen, G Maglieri, A Jacobsen, J Højfeldt, ... Nature Communications 6 (1), 6967, 2015 | 182 | 2015 |
| Variegated gene expression caused by cell-specific long-range DNA interactions D Noordermeer, E De Wit, P Klous, H Van De Werken, M Simonis, ... Nature cell biology 13 (8), 944-951, 2011 | 181 | 2011 |
| Endogenous WNT signals mediate BMP-induced and spontaneous differentiation of epiblast stem cells and human embryonic stem cells D Kurek, A Neagu, M Tastemel, N Tüysüz, J Lehmann, ... Stem cell reports 4 (1), 114-128, 2015 | 165 | 2015 |
| Decoding the DNA methylome of mantle cell lymphoma in the light of the entire B cell lineage AC Queiros, R Beekman, R Vilarrasa-Blasi, M Duran-Ferrer, G Clot, ... Cancer cell 30 (5), 806-821, 2016 | 150 | 2016 |
| Gene length corrected trimmed mean of M-values (GeTMM) processing of RNA-seq data performs similarly in intersample analyses while improving intrasample comparisons M Smid, RRJ Coebergh van den Braak, HJG van de Werken, J van Riet, ... BMC bioinformatics 19, 1-13, 2018 | 137 | 2018 |
| Identification of the Missing Links in Prokaryotic Pentose Oxidation Pathways : Evidence for enzyme recruiment SJJ Brouns, J Walther, APL Snijders, HJG van de Werken, ... Journal of Biological Chemistry 281 (37), 27378-27388, 2006 | 126 | 2006 |
| DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus LTJ Kaaij, M van de Wetering, F Fang, B Decato, A Molaro, ... Genome biology 14, 1-15, 2013 | 124 | 2013 |
| Transcriptome analysis of infection of the archaeon Sulfolobus solfataricus with Sulfolobus turreted icosahedral virus AC Ortmann, SK Brumfield, J Walther, K McInnerney, SJJ Brouns, ... Journal of virology 82 (10), 4874-4883, 2008 | 104 | 2008 |
| Targeted Chromatin Capture (T2C): a novel high resolution high throughput method to detect genomic interactions and regulatory elements P Kolovos, HJG van de Werken, N Kepper, J Zuin, RWW Brouwer, ... Epigenetics and Chromatin 7, 1-17, 2014 | 98 | 2014 |
Job van RietGerman Cancer Research Center (DKFZ)Verified email at dkfz-heidelberg.de
