Discovery of potent antiallodynic agents for neuropathic pain targeting P2X3 receptors YH Jung, YO Kim, H Lin, JH Cho, JH Park, SD Lee, J Bae, KM Kang, ... ACS Chemical Neuroscience 8 (7), 1465-1478, 2017 | 30 | 2017 |
Structure–Activity Relationships and Optimization of 3,5-Dichloropyridine Derivatives As Novel P2X7 Receptor Antagonists WG Lee, SD Lee, JH Cho, Y Jung, J Kim, TT Hien, KW Kang, H Ko, ... Journal of Medicinal Chemistry 55 (8), 3687-3698, 2012 | 27 | 2012 |
P2Y14 Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model F Mufti, YH Jung, LA Giancotti, J Yu, Z Chen, NB Phung, KA Jacobson, ... ACS Medicinal Chemistry Letters 11 (6), 1281-1286, 2020 | 25 | 2020 |
Exploration of Alternative Scaffolds for P2Y14 Receptor Antagonists Containing a Biaryl Core YH Jung, J Yu, Z Wen, V Salmaso, TP Karcz, NB Phung, Z Chen, S Duca, ... Journal of medicinal chemistry 63 (17), 9563-9589, 2020 | 23 | 2020 |
Design and synthesis of potent and selective P2X3 receptor antagonists derived from PPADS as potential pain modulators JH Cho, KY Jung, Y Jung, MH Kim, H Ko, CS Park, YC Kim European Journal of Medicinal Chemistry 70, 811-830, 2013 | 23 | 2013 |
Adipocyte P2Y14 receptors play a key role in regulating whole-body glucose and lipid homeostasis S Jain, SP Pydi, YH Jung, M Scortichini, EL Kesner, TP Karcz, DN Cook, ... JCI insight 6 (10), 2021 | 18 | 2021 |
Structure–Activity Relationship of Heterocyclic P2Y14 Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres YH Jung, V Salmaso, Z Wen, JM Bennett, NB Phung, DI Lieberman, ... Journal of medicinal chemistry 64 (8), 5099-5122, 2021 | 13 | 2021 |
Isobolographic analysis of drug combinations with intrathecal BRL52537 (κ-opioid agonist), pregabalin (calcium channel modulator), AF 353 (P2X3 receptor antagonist), and … YH Jung, YO Kim, JH Han, YC Kim, MH Yoon Anesthesia & Analgesia 125 (2), 670-677, 2017 | 12 | 2017 |
Structure activity relationship of 3-nitro-2-(trifluoromethyl)-2H-chromene derivatives as P2Y6 receptor antagonists YH Jung, S Jain, V Gopinatth, NB Phung, ZG Gao, KA Jacobson Bioorganic & medicinal chemistry letters 41, 128008, 2021 | 11 | 2021 |
Biological Evaluation of 5′-(N-Ethylcarboxamido)adenosine Analogues as Grp94-Selective Inhibitors DK Tosh, CM Brackett, YH Jung, ZG Gao, M Banerjee, BSJ Blagg, ... ACS Medicinal Chemistry Letters 12 (3), 373-379, 2021 | 10 | 2021 |
Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y6 receptor antagonists YH Jung, Q Shah, SA Lewicki, A Pramanik, V Gopinatth, J Pelletier, ... Bioorganic & medicinal chemistry letters 75, 128981, 2022 | 6 | 2022 |
Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y14R Antagonist Z Wen, V Salmaso, YH Jung, NB Phung, V Gopinatth, Q Shah, ... Journal of medicinal chemistry 65 (4), 3434-3459, 2022 | 6 | 2022 |
Structure activity relationship of 2-arylalkynyl-adenine derivatives as human A 3 adenosine receptor antagonists J Yu, P Mannes, YH Jung, A Ciancetta, A Bitant, DI Lieberman, ... Medchemcomm 9 (11), 1920-1932, 2018 | 5 | 2018 |
Effects of purinergic receptor deletion or pharmacologic modulation on pulmonary inflammation in mice GS Whitehead, TP Karcz, DK Tosh, YH Jung, Z Wen, RG Campbell, ... ACS Pharmacology & Translational Science 5 (10), 973-984, 2022 | 4 | 2022 |
Heterocyclic P2Y14 receptor antagonists KA Jacobson, J Yu, A Ciancetta, Z Wen, YH Jung WO 157417, A1, 2019 | 3 | 2019 |
Alicyclic Ring Size Variation of 4-Phenyl-2-naphthoic Acid Derivatives as P2Y14 Receptor Antagonists Z Wen, A Pramanik, SA Lewicki, YH Jung, ZG Gao, JCR Randle, C Cronin, ... Journal of Medicinal Chemistry 66 (13), 9076-9094, 2023 | 1 | 2023 |
Novel 5-hydroxy pyridine-based compound for use as p2x1 and p2x3 receptor antagonist and pharmaceutical composition comprising same YC Kim, YH Jung US Patent App. 16/494,212, 2020 | 1 | 2020 |
Heterocyclic P2Y14 receptor antagonists KA Jacobson, J Yu, A Ciancetta, Z Wen, YH Jung US Patent 11,584,736, 2023 | | 2023 |
5-hydroxy pyridine-based compound for use as P2X1 and P2X3 receptor antagonist and pharmaceutical composition comprising same YC Kim, YH Jung US Patent 11,319,289, 2022 | | 2022 |
P2Y14 receptor inhibition reverses mechanical sensitivity in a mouse model of chronic neuropathic pain F Mufti, YH Jung, LA Giancotti, J Yu, Z Chen, NB Phung, KA Jacobson, ... The FASEB Journal 36, 2022 | | 2022 |