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Sriram Aiyer
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BET proteins promote efficient murine leukemia virus integration at transcription start sites
A Sharma, RC Larue, MR Plumb, N Malani, F Male, A Slaughter, JJ Kessl, ...
Proceedings of the National Academy of Sciences 110 (29), 12036-12041, 2013
2072013
Sub-2 Ewald curvature corrected structure of an AAV2 capsid variant
YZ Tan, S Aiyer, M Mietzsch, JA Hull, R McKenna, J Grieger, RJ Samulski, ...
Nature communications 9 (1), 3628, 2018
1102018
Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction
S Aiyer, GVT Swapna, N Malani, JM Aramini, WM Schneider, MR Plumb, ...
Nucleic acids research 42 (9), 5917-5928, 2014
752014
Viral DNA tethering domains complement replication-defective mutations in the p12 protein of MuLV Gag
WM Schneider, JD Brzezinski, S Aiyer, N Malani, M Gyuricza, ...
Proceedings of the National Academy of Sciences 110 (23), 9487-9492, 2013
502013
Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes
RC Larue, MR Plumb, BL Crowe, N Shkriabai, A Sharma, J DiFiore, ...
Nucleic acids research 42 (8), 4868-4881, 2014
452014
MuLV IN mutants responsive to HDAC inhibitors enhance transcription from unintegrated retroviral DNA
WM Schneider, D Wu, V Amin, S Aiyer, MJ Roth
Virology 426 (2), 188-196, 2012
302012
Structural and sequencing analysis of local target DNA recognition by MLV integrase
S Aiyer, P Rossi, N Malani, WM Schneider, A Chandar, FD Bushman, ...
Nucleic acids research 43 (11), 5647-5663, 2015
262015
A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins
S Aiyer, GVT Swapna, LC Ma, G Liu, J Hao, G Chalmers, BC Jacobs, ...
Structure 29 (8), 886-898. e6, 2021
222021
Evaluating local and directional resolution of cryo-EM density maps
S Aiyer, C Zhang, PR Baldwin, D Lyumkis
cryoEM: Methods and Protocols, 161-187, 2021
212021
Disrupting MLV integrase: BET protein interaction biases integration into quiescent chromatin and delays but does not eliminate tumor activation in a MYC/Runx2 mouse model
L Loyola, V Achuthan, K Gilroy, G Borland, A Kilbey, N Mackay, M Bell, ...
PLoS pathogens 15 (12), e1008154, 2019
132019
X‐ray crystal structure of the N‐terminal region of M oloney murine leukemia virus integrase and its implications for viral DNA recognition
R Guan, S Aiyer, ML Cote, R Xiao, M Jiang, TB Acton, MJ Roth, ...
Proteins: Structure, Function, and Bioinformatics 85 (4), 647-656, 2017
122017
Development of an enzyme-linked immunosorbent assay based on the murine leukemia virus p30 capsid protein
DT Wu, S Aiyer, RA Villanueva, MJ Roth
Journal of virological methods 193 (2), 332-336, 2013
102013
B-to-A transition in target DNA during retroviral integration
IK Jźwik, W Li, DW Zhang, D Wong, J Grawenhoff, A Ballandras-Colas, ...
Nucleic Acids Research 50 (15), 8898-8918, 2022
82022
Single-particle cryo-EM data collection with stage tilt using leginon
S Aiyer, TS Strutzenberg, ME Bowman, JP Noel, D Lyumkis
JoVE (Journal of Visualized Experiments), e64136, 2022
52022
Overcoming resolution attenuation during tilted cryo-EM data collection
S Aiyer, PR Baldwin, SM Tan, Z Shan, J Oh, A Mehrani, ME Bowman, ...
Nature communications 15 (1), 389, 2024
32024
Assembly of the Bacterial Ribosome with Circularly Permuted rRNA
X Dong, K Sheng, LFR Gebert, S Aiyer, IJ MacRae, D Lyumkis, ...
bioRxiv, 2024
12024
Domain consolidation in Bacterial 50S assembly revealed by Anti-Sense Oligonucleotide Probing
K Sheng, X Dong, S Aiyer, J Lee, SD Marquardt, D Lyumkis, ...
bioRxiv, 2024
2024
Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding
T Jing, Z Shan, T Dinh, A Biswas, S Jang, J Greenwood, M Li, Z Zhang, ...
bioRxiv, 2024
2024
Anisotropy in CryoEM Resolution is Dominated by Preferred Orientations, but not Structure Factors: A Study Using a Highly Symmetric Structure
PR Baldwin, S Aiyer, TS Strutzenberg, D Lyumkis
Microscopy and Microanalysis 29 (Supplement_1), 1021-1023, 2023
2023
AAV Capsid Dynamics at the 5-Fold Pore Controls Genome Release
JA Hull, M Mietzsch, YZ Tan, S Aiyer, A Bennett, R Lakshman, P Chipman, ...
MOLECULAR THERAPY 30 (4), 205-206, 2022
2022
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