| Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls 1958 Birth Cohort Controls Jones Richard W. 18 McArdle Wendy L. 18 Ring ... Nature 447 (7145), 661-678, 2007 | 9327 | 2007 |
| Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119-124, 2012 | 5252* | 2012 |
| Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease JC Barrett, S Hansoul, DL Nicolae, JH Cho, RH Duerr, JD Rioux, SR Brant, ... Nature genetics 40 (8), 955-962, 2008 | 3217 | 2008 |
| Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ... Nature genetics 42 (12), 1118-1125, 2010 | 3128 | 2010 |
| Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246-252, 2011 | 1697 | 2011 |
| Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility M Parkes, JC Barrett, NJ Prescott, M Tremelling, CA Anderson, SA Fisher, ... Nature genetics 39 (7), 830-832, 2007 | 1432 | 2007 |
| Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants 1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ... Nature genetics 39 (11), 1329-1337, 2007 | 1422 | 2007 |
| Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease KM De Lange, L Moutsianas, JC Lee, CA Lamb, Y Luo, NA Kennedy, ... Nature genetics 49 (2), 256-261, 2017 | 1190 | 2017 |
| Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls Nature 464 (7289), 713-720, 2010 | 931 | 2010 |
| The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease AP Cuthbert, SA Fisher, MM Mirza, K King, J Hampe, PJP Croucher, ... Gastroenterology 122 (4), 867-874, 2002 | 925 | 2002 |
| Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig, T Ahmad, ... The Lancet 387 (10014), 156-167, 2016 | 822 | 2016 |
| Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A S Nejentsev, JMM Howson, NM Walker, J Szeszko, SF Field, HE Stevens, ... Nature 450 (7171), 887-892, 2007 | 699 | 2007 |
| Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region Data and Analysis Group: Spencer Chris CA chris. spencer@ well. ox. ac. uk 5 ... Nature genetics 41 (12), 1330-1334, 2009 | 622 | 2009 |
| Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ... The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019 | 553 | 2019 |
| Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease SA Fisher, M Tremelling, CA Anderson, R Gwilliam, S Bumpstead, ... Nature genetics 40 (6), 710-712, 2008 | 545 | 2008 |
| Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist JC Mansfield, H Holden, JK Tarlow, FS Di Giovine, TL McDowell, ... Gastroenterology 106 (3), 637-642, 1994 | 524 | 1994 |
| Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial S Vermeire, S O'Byrne, M Keir, M Williams, TT Lu, JC Mansfield, CA Lamb, ... The Lancet 384 (9940), 309-318, 2014 | 498 | 2014 |
| A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn’s disease and is independent of CARD15 and IBD5 NJ Prescott, SA Fisher, A Franke, J Hampe, CM Onnie, D Soars, ... Gastroenterology 132 (5), 1665-1671, 2007 | 395 | 2007 |
| High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ... Nature genetics 47 (2), 172-179, 2015 | 329 | 2015 |
| HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease A Sazonovs, NA Kennedy, L Moutsianas, GA Heap, DL Rice, M Reppell, ... Gastroenterology 158 (1), 189-199, 2020 | 303 | 2020 |
