| Decreased α-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's diseas L Lannfelt, H Basun, LO Wahlund, BA Rowe, SL Wagner Nature medicine 1 (8), 829-832, 1995 | 225 | 1995 |
| A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain JA O'Brien, W Lemaire, M Wittmann, MA Jacobson, SN Ha, DD Wisnoski, ... Journal of Pharmacology and Experimental Therapeutics 309 (2), 568-577, 2004 | 201 | 2004 |
| Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2 H Schaffhauser, BA Rowe, S Morales, LE Chavez-Noriega, R Yin, ... Molecular pharmacology 64 (4), 798-810, 2003 | 196 | 2003 |
| Reductions in β-amyloid concentrations in vivo by the γ-secretase inhibitors BMS-289948 and BMS-299897 JJ Anderson, G Holtz, PP Baskin, M Turner, B Rowe, B Wang, ... Biochemical pharmacology 69 (4), 689-698, 2005 | 140 | 2005 |
| [3H] Methoxymethyl-3-[(2-methyl-1, 3-thiazol-4-yl) ethynyl] pyridine binding to metabotropic glutamate receptor subtype 5 in rodent brain: in vitro and in vivo characterization JJ Anderson, SP Rao, B Rowe, DR Giracello, G Holtz, DF Chapman, ... Journal of Pharmacology and Experimental Therapeutics 303 (3), 1044-1051, 2002 | 113 | 2002 |
| Cerebrospinal fluid levels of α-secretase—Cleaved soluble amyloid precursor protein mirror cognition in a Swedish family with Alzheimer disease and a gene mutation O Almkvist, H Basun, SL Wagner, BA Rowe, LO Wahlund, L Lannfelt Archives of neurology 54 (5), 641-644, 1997 | 100 | 1997 |
| Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge DS Lorrain, H Schaffhauser, UC Campbell, CS Baccei, LD Correa, ... Neuropsychopharmacology 28 (9), 1622-1632, 2003 | 95 | 2003 |
| Phenyl-tetrazolyl acetophenones: discovery of positive allosteric potentiatiors for the metabotropic glutamate 2 receptor AB Pinkerton, JM Vernier, H Schaffhauser, BA Rowe, UC Campbell, ... Journal of medicinal chemistry 47 (18), 4595-4599, 2004 | 77 | 2004 |
| Biphenyl-indanones: allosteric potentiators of the metabotropic glutamate subtype 2 receptor C Bonnefous, JM Vernier, JH Hutchinson, MF Gardner, M Cramer, ... Bioorganic & Medicinal Chemistry Letters 15 (19), 4354-4358, 2005 | 69 | 2005 |
| Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators AB Pinkerton, RV Cube, JH Hutchinson, JK James, MF Gardner, BA Rowe, ... Bioorganic & medicinal chemistry letters 15 (6), 1565-1571, 2005 | 62 | 2005 |
| Benzazoles as allosteric potentiators of metabotropic glutamate receptor 2 (mGluR2): efficacy in an animal model for schizophrenia SP Govek, C Bonnefous, JH Hutchinson, T Kamenecka, J McQuiston, ... Bioorganic & medicinal chemistry letters 15 (18), 4068-4072, 2005 | 50 | 2005 |
| Transposition of three amino acids transforms the human metabotropic glutamate receptor (mGluR)-3-positive allosteric modulation site to mGluR2, and additional characterization … BA Rowe, H Schaffhauser, S Morales, LS Lubbers, C Bonnefous, ... Journal of Pharmacology and Experimental Therapeutics 326 (1), 240-251, 2008 | 49 | 2008 |
| Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 1: Identification and synthesis of phenyl-tetrazolyl acetophenones AB Pinkerton, RV Cube, JH Hutchinson, BA Rowe, H Schaffhauser, ... Bioorganic & medicinal chemistry letters 14 (21), 5329-5332, 2004 | 45 | 2004 |
| 3-(2-Ethoxy-4-{4-[3-hydroxy-2-methyl-4-(3-methylbutanoyl) phenoxy] butoxy} phenyl) propanoic acid: a brain penetrant allosteric potentiator at the metabotropic glutamate … RV Cube, JM Vernier, JH Hutchinson, MF Gardner, JK James, BA Rowe, ... Bioorganic & medicinal chemistry letters 15 (9), 2389-2393, 2005 | 39 | 2005 |
| Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 2: 4-thiopyridyl acetophenones as non-tetrazole containing mGlu2 receptor potentiators AB Pinkerton, RV Cube, JH Hutchinson, JK James, MF Gardner, ... Bioorganic & medicinal chemistry letters 14 (23), 5867-5872, 2004 | 35 | 2004 |
| Synthesis and evaluation of a new series of Neuropeptide S receptor antagonists JY Melamed, AE Zartman, NR Kett, AL Gotter, VN Uebele, DR Reiss, ... Bioorganic & medicinal chemistry letters 20 (15), 4700-4703, 2010 | 28 | 2010 |
| Pyrimidine methyl anilines: selective potentiators for the metabotropic glutamate 2 receptor E Hu, PC Chua, L Tehrani, JY Nagasawa, AB Pinkerton, BA Rowe, ... Bioorganic & medicinal chemistry letters 14 (20), 5071-5074, 2004 | 18 | 2004 |
| Peptide and peptide analog protease inhibitors BA Rowe, RS Siegel, SL Wagner US Patent 5,714,471, 1998 | 17 | 1998 |
| Peptide and peptide analog protease inhibitors 2 IA McDonald, E Albrecht, B Munoz, BA Rowe, RS Siegel, SL Wagner, ... US Patent 5,962,419, 1999 | 15 | 1999 |
| MK-7128, a novel CB1 receptor inverse agonist, improves scopolamine-induced learning and memory deficits in mice GM Dillon, LS Lubbers, MT Ferguson, JZ Lao, RRC Huang, JC Xiao, ... Behavioural Pharmacology 22 (2), 91-100, 2011 | 9 | 2011 |
