Puneet Opal
Puneet Opal
Northwestern University
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Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice
CJ Cummings, Y Sun, P Opal, B Antalffy, R Mestril, HT Orr, WH Dillmann, ...
Human molecular genetics 10 (14), 1511-1518, 2001
The function of intermediate filaments in cell shape and cytoskeletal integrity.
RD Goldman, S Khuon, YH Chou, P Opal, PM Steinert
The Journal of cell biology 134 (4), 971-983, 1996
Intermediate filament dynamics
JE Eriksson, P Opal, RD Goldman
Current Opinion in Cell Biology 4 (1), 99-104, 1992
Intrafamilial phenotypic variability of the DYT1 dystonia: From asymptomatic TOR1A gene carrier status to dystonic storm
P Opal, R Tintner, J Jankovic, J Leung, XO Breakefield, J Friedman, ...
Movement disorders: official journal of the Movement Disorder Society 17 (2 …, 2002
Giant axonal neuropathy–associated gigaxonin mutations impair intermediate filament protein degradation
S Mahammad, SNP Murthy, A Didonna, B Grin, E Israeli, R Perrot, ...
The Journal of clinical investigation 123 (5), 1964-1975, 2013
The promise and perils of HDAC inhibitors in neurodegeneration
A Didonna, P Opal
Annals of clinical and translational neurology 2 (1), 79-101, 2015
Neuronal atrophy early in degenerative ataxia is a compensatory mechanism to regulate membrane excitability
JM Dell'Orco, AH Wasserman, R Chopra, MAC Ingram, YS Hu, V Singh, ...
Journal of Neuroscience 35 (32), 11292-11307, 2015
Paraneoplastic cerebellar degeneration with anti‐Yo antibodies–a review
A Venkatraman, P Opal
Annals of clinical and translational neurology 3 (8), 655-663, 2016
Vascular endothelial growth factor ameliorates the ataxic phenotype in a mouse model of spinocerebellar ataxia type 1
M Cvetanovic, JM Patel, HH Marti, AR Kini, P Opal
Nature medicine 17 (11), 1445-1447, 2011
Early activation of microglia and astrocytes in mouse models of spinocerebellar ataxia type 1
M Cvetanovic, M Ingram, H Orr, P Opal
Neuroscience 289, 289-299, 2015
The relative roles of specific N-and C-terminal phosphorylation sites in the disassembly of intermediate filament in mitotic BHK-21 cells
YH Chou, P Opal, RA Quinlan, RD Goldman
Journal of cell science 109 (4), 817-826, 1996
The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disorders
A Didonna, P Opal
Molecular neurodegeneration 14 (1), 1-10, 2019
Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis
P Opal, JJ Garcia, F Propst, A Matilla, HT Orr, HY Zoghbi
Journal of Biological Chemistry 278 (36), 34691-34699, 2003
Alterations in neural intermediate filament organization: functional implications and the induction of pathological changes related to motor neuron disease
K Straube-West, PA Loomis, P Opal, RD Goldman
Journal of cell science 109 (9), 2319-2329, 1996
In cis autosomal dominant mutation of Senataxin associated with tremor/ataxia syndrome
AG Bassuk, YZ Chen, SD Batish, N Nagan, P Opal, PF Chance, ...
Neurogenetics 8, 45-49, 2007
The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1
A Venkatraman, YS Hu, A Didonna, M Cvetanovic, A Krbanjevic, ...
Human molecular genetics 23 (14), 3733-3745, 2014
Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1
CR Edamakanti, J Do, A Didonna, M Martina, P Opal
The Journal of clinical investigation 128 (6), 2252-2265, 2018
The role of LANP and ataxin 1 in E4F‐mediated transcriptional repression
M Cvetanovic, RJ Rooney, JJ Garcia, N Toporovskaya, HY Zoghbi, P Opal
EMBO reports 8 (7), 671-677, 2007
Generation and characterization of LANP/pp32 null mice
P Opal, JJ Garcia, AE McCall, B Xu, EJ Weeber, JD Sweatt, HT Orr, ...
Molecular and cellular biology 24 (8), 3140-3149, 2004
The role of chaperones in polyglutamine disease
P Opal, HY Zoghbi
Trends in molecular medicine 8 (5), 232-236, 2002
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