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Pradeepa Madapura
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Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing
MM Pradeepa, HG Sutherland, J Ule, GR Grimes, WA Bickmore
PLoS genetics 8 (5), e1002717, 2012
3812012
Histone H3 globular domain acetylation identifies a new class of enhancers
MM Pradeepa, GR Grimes, Y Kumar, G Olley, GCA Taylor, R Schneider, ...
Nature genetics 48 (6), 681-686, 2016
2542016
H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction
GCA Taylor, R Eskeland, B Hekimoglu-Balkan, MM Pradeepa, ...
Genome research 23 (12), 2053-2065, 2013
2182013
The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development
RS Illingworth, M Moffat, AR Mann, CJ Hunter, MM Pradeepa, IR Adams, ...
Genes & development 29 (18), 1897-1902, 2015
1752015
BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome
G Olley, M Ansari, H Bengani, GR Grimes, J Rhodes, A von Kriegsheim, ...
Nature Genetics 50 (3), 329-332, 2018
1282018
Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage
R Marin, D Cortez, F Lamanna, MM Pradeepa, E Leushkin, P Julien, ...
Genome research 27 (12), 1974-1987, 2017
862017
Causal role of histone acetylations in enhancer function
MM Pradeepa
Transcription 8 (1), 40-47, 2017
742017
Chromatin remodeling during mammalian spermatogenesis: role of testis specific histone variants and transition proteins.
MM Pradeepa, MR Rao
Society of Reproduction and Fertility supplement 63, 1-10, 2007
632007
An interferon regulated MicroRNA provides broad cell-intrinsic antiviral immunity through multihit host-directed targeting of the sterol pathway
KA Robertson, WY Hsieh, T Forster, M Blanc, H Lu, PJ Crick, E Yutuc, ...
PLoS biology 14 (3), e1002364, 2016
452016
Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus
MM Pradeepa, S Manjunatha, V Sathish, S Agrawal, MRS Rao
Molecular and cellular biology 28 (13), 4331-4341, 2008
432008
Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip
MM Pradeepa, F McKenna, GCA Taylor, H Bengani, GR Grimes, AJ Wood, ...
PLoS genetics 13 (4), e1006677, 2017
362017
Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins
MM Pradeepa, GR Grimes, GCA Taylor, HG Sutherland, WA Bickmore
Nucleic acids research 42 (14), 9021-9032, 2014
362014
Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states
F Rodriguez-Algarra, RAE Seaborne, AF Danson, S Yildizoglu, ...
Genome biology 23 (1), 54, 2022
272022
Mapping of post-translational modifications of transition proteins, TP1 and TP2, and identification of protein arginine methyltransferase 4 and lysine methyltransferase 7 as …
N Gupta, MP Madapura, UA Bhat, MRS Rao
Journal of Biological Chemistry 290 (19), 12101-12122, 2015
262015
H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function
D Pal, M Patel, F Boulet, J Sundarraj, OA Grant, MR Branco, S Basu, ...
Nature structural & molecular biology 30 (7), 935-947, 2023
242023
Acetylation of transition protein 2 (TP2) by KAT3B (p300) alters its DNA condensation property and interaction with putative histone chaperone NPM3
MM Pradeepa, G Nikhil, AH Kishore, GN Bharath, TK Kundu, MRS Rao
Journal of biological chemistry 284 (43), 29956-29967, 2009
222009
Spatiotemporal organization of AT-and GC-rich DNA and their association with transition proteins TP1 and TP2 in rat condensing spermatids
U Kolthur-Seetharam, MM Pradeepa, N Gupta, R Narayanaswamy, ...
Journal of Histochemistry & Cytochemistry 57 (10), 951-962, 2009
222009
Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect
G Olley, MM Pradeepa, GR Grimes, S Piquet, SE Polo, DR FitzPatrick, ...
Nature Communications 12 (1), 3127, 2021
212021
Germline thymidylate synthase deficiency impacts nucleotide metabolism and causes dyskeratosis congenita
H Tummala, A Walne, R Buccafusca, J Alnajar, A Szabo, P Robinson, ...
The American Journal of Human Genetics 109 (8), 1472-1483, 2022
172022
H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci
J Sundarraj, GCA Taylor, A von Kriegsheim, MM Pradeepa
Wellcome Open Research 2, 2017
122017
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Articles 1–20