Inhibition of endogenous TGF-β during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair A Scharstuhl, HL Glansbeek, HM van Beuningen, EL Vitters, ... The Journal of Immunology 169 (1), 507-514, 2002 | 312 | 2002 |
Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity EN Blaney Davidson, A Scharstuhl, EL Vitters, PM Van Der Kraan, ... Arthritis research & therapy 7, 1-10, 2005 | 297 | 2005 |
Chondrogenic potential of human adult mesenchymal stem cells is independent of age or osteoarthritis etiology A Scharstuhl, B Schewe, K Benz, C Gaissmaier, HJ Bühring, R Stoop Stem cells 25 (12), 3244-3251, 2007 | 259 | 2007 |
Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor β/bone morphogenetic protein inhibitors during experimental … A Scharstuhl, EL Vitters, PM van der Kraan, WB van den Berg Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 233 | 2003 |
The role of reactive oxygen species in apoptosis of the diabetic kidney F Wagener, D Dekker, JH Berden, A Scharstuhl, J Van der Vlag Apoptosis 14, 1451-1458, 2009 | 173 | 2009 |
Growth factors and cartilage repair WB van den Berg, PM van der Kraan, A Scharstuhl, HM van Beuningen Clinical Orthopaedics and Related Research® 391, S244-S250, 2001 | 131 | 2001 |
Curcumin‐induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation A Scharstuhl, HAM Mutsaers, SWC Pennings, WA Szarek, FGM Russel, ... Journal of cellular and molecular medicine 13 (4), 712-725, 2009 | 128 | 2009 |
Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis A Scharstuhl, HAM Mutsaers, SWC Pennings, FGM Russel, FA Wagener PloS one 4 (8), e6688, 2009 | 87 | 2009 |
Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice A Scharstuhl, HM Van Beuningen, EL Vitters, PM Van der Kraan, ... Annals of the rheumatic diseases 61 (12), 1095-1098, 2002 | 79 | 2002 |
Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-β-mediated chondrocyte proliferation and proteoglycan synthesis A Scharstuhl, R Diepens, J Lensen, E Vitters, H van Beuningen, ... Osteoarthritis and cartilage 11 (11), 773-782, 2003 | 44 | 2003 |
The heme-heme oxygenase system in wound healing; implications for scar formation F ADTG Wagener, A Scharstuhl, R M Tyrrell, J W Von den Hoff, ... Current drug targets 11 (12), 1571-1585, 2010 | 28 | 2010 |
Cell-type-specific downregulation of heme oxygenase-1 by lipopolysaccharide via Bach1 in primary human mononuclear cells MJ Dorresteijn, A Paine, E Zilian, MGE Fenten, E Frenzel, ... Free Radical Biology and Medicine 78, 224-232, 2015 | 26 | 2015 |
Heme oxygenase-1 and breast cancer resistance protein protect against hemeinduced toxicity F ADTG Wagener, A CA Dankers, F van Summeren, A Scharstuhl, ... Current pharmaceutical design 19 (15), 2698-2707, 2013 | 26 | 2013 |
Low heme oxygenase-1 levels in patients with systemic sclerosis are associated with an altered Toll-like receptor response: another role for CXCL4? L van Bon, M Cossu, A Scharstuhl, BWC Pennings, MC Vonk, HJ Vreman, ... Rheumatology 55 (11), 2066-2073, 2016 | 24 | 2016 |
Delayed cutaneous wound closure in HO‐2 deficient mice despite normal HO‐1 expression DMS Lundvig, A Scharstuhl, NAJ Cremers, SWC Pennings, J te Paske, ... Journal of Cellular and Molecular Medicine 18 (12), 2488-2498, 2014 | 16 | 2014 |
Large scale protein production of the extracellular domain of the transforming growth factor-β type II receptor using the Pichia pastoris expression system A Scharstuhl, H Glansbeek, EL Vitters, PM van der Kraan, ... Journal of Chromatography B 786 (1-2), 271-277, 2003 | 8 | 2003 |
Hydrazine-induced liver toxicity is enhanced by glutathione depletion but is not mediated by oxidative stress in HepG2 cells. E Olthof, A Tostmann, WHM Peters, HMJ Roelofs, FA Wagener, ... | 5 | 2009 |
Curcumin-induced apoptosis of human dermal fibroblasts is mediated by apoptosis inducing factor (Aif) and not by caspases A Scharstuhl, R Mutsaers, B Pennings, M Zizi, F Russel, F Wagener WOUND REPAIR AND REGENERATION 17 (2), A18-A18, 2009 | 2 | 2009 |
In vivo inhibition of TGF-beta activity inhibits osteophyte formation and decreases cartilage proteoglycan content and synthesis. A Scharstuhl, EL Vitters, HM van Beuningen, PM van der Krann, ... ARTHRITIS AND RHEUMATISM 44 (9), S306-S306, 2001 | 2 | 2001 |
WOUND CLOSURE IS DELAYED IN HEME OXYGENASE-2 KNOCK-OUT MICE BUT INCREASED IN HYPERBILIRUBINEMIC RATS A Scharstuhl, B Pennings, J te Paske, R Regan, R van Rheden, F Russel, ... WOUND REPAIR AND REGENERATION 18 (6), A93-A93, 2010 | 1 | 2010 |