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Frederik Lermyte
Frederik Lermyte
Verified email at tu-darmstadt.de - Homepage
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Year
Metallodrugs are unique: opportunities and challenges of discovery and development
EJ Anthony, EM Bolitho, HE Bridgewater, OWL Carter, JM Donnelly, ...
Chemical science 11 (48), 12888-12917, 2020
4062020
Top or middle? Up or down? Toward a standard lexicon for protein top-down and allied mass spectrometry approaches
F Lermyte, YO Tsybin, PB O’Connor, JA Loo
Journal of The American Society for Mass Spectrometry 30 (7), 1149-1157, 2019
1262019
ETD allows for native surface mapping of a 150 kDa noncovalent complex on a commercial Q-TWIMS-TOF instrument
F Lermyte, A Konijnenberg, JP Williams, JM Brown, D Valkenborg, ...
Journal of The American Society for Mass Spectrometry 25 (3), 343-350, 2014
1072014
Radical solutions: Principles and application of electron‐based dissociation in mass spectrometry‐based analysis of protein structure
F Lermyte, D Valkenborg, JA Loo, F Sobott
Mass spectrometry reviews 37 (6), 750-771, 2018
982018
Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects
J Everett, JF Collingwood, V Tjendana-Tjhin, J Brooks, F Lermyte, ...
Nanoscale 10 (25), 11782-11796, 2018
962018
Higher-order structural characterisation of native proteins and complexes by top-down mass spectrometry
M Zhou, C Lantz, KA Brown, Y Ge, L Paša-Tolić, JA Loo, F Lermyte
Chemical science 11 (48), 12918-12936, 2020
942020
Electron transfer dissociation provides higher‐order structural information of native and partially unfolded protein complexes
F Lermyte, F Sobott
Proteomics 15 (16), 2813-2822, 2015
812015
Extensive Charge Reduction and Dissociation of Intact Protein Complexes Following Electron Transfer on a Quadrupole-Ion Mobility-Time-of-Flight MS.
F Lermyte, JP Williams, JM Brown, EM Martin, F Sobott
Journal of The American Society for Mass Spectrometry 26 (7), 1068-1076, 2015
722015
Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility-Mass Spectrometer
JP Williams, LJ Morrison, JM Brown, JS Beckman, VG Voinov, F Lermyte
Analytical Chemistry 92 (5), 3674-3681, 2020
592020
Metal Ion Binding to the Amyloid β Monomer Studied by Native Top-Down FTICR Mass Spectrometry
F Lermyte, J Everett, YPY Lam, CA Wootton, J Brooks, MP Barrow, ...
Journal of The American Society for Mass Spectrometry 30 (10), 2123-2134, 2019
582019
Biogenic metallic elements in the human brain?
J Everett, F Lermyte, J Brooks, V Tjendana-Tjhin, G Plascencia-Villa, ...
Science Advances 7 (24), eabf6707, 2021
552021
Iron stored in ferritin is chemically reduced in the presence of aggregating Aβ (1-42)
J Everett, J Brooks, F Lermyte, PB O’Connor, PJ Sadler, J Dobson, ...
Scientific Reports 10 (1), 10332, 2020
382020
Conformational Space and Stability of ETD Charge Reduction Products of Ubiquitin.
F Lermyte, MK Łącki, D Valkenborg, A Gambin, F Sobott
Journal of The American Society for Mass Spectrometry 28 (1), 69-76, 2017
332017
Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1
M Heirbaut, F Lermyte, EM Martin, S Beelen, F Sobott, SV Strelkov, ...
Journal of Biological Chemistry 292 (24), 9944-9957, 2017
322017
Characterization of top-down ETD in a travelling-wave ion guide
F Lermyte, T Verschueren, JM Brown, JP Williams, D Valkenborg, ...
Methods 89, 22-29, 2015
312015
The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain
M Heirbaut, F Lermyte, EM Martin, S Beelen, T Verschueren, F Sobott, ...
Archives of biochemistry and biophysics 610, 41-50, 2016
302016
Gas-phase microsolvation of ubiquitin: investigation of crown ether complexation sites using ion mobility-mass spectrometry
M Göth, F Lermyte, XJ Schmitt, S Warnke, G von Helden, F Sobott, ...
Analyst 141 (19), 5502-5510, 2016
262016
Top-down/bottom-up mass spectrometry workflow using dissolvable polyacrylamide gels
N Takemori, A Takemori, P Wongkongkathep, M Nshanian, RRO Loo, ...
Analytical Chemistry 89 (16), 8244-8250, 2017
242017
Understanding reaction pathways in top-down ETD by dissecting isotope distributions: A mammoth task
F Lermyte, MK Łącki, D Valkenborg, G Baggerman, A Gambin, F Sobott
International Journal of Mass Spectrometry 390, 146-154, 2015
242015
Emerging Approaches to Investigate the Influence of Transition Metals in the Proteinopathies
F Lermyte, J Everett, J Brooks, F Bellingeri, K Billimoria, PJ Sadler, ...
Cells 8 (10), 1231, 2019
222019
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