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Dr. Ahmad Al-Khliefat
Dr. Ahmad Al-Khliefat
Verified email at kcl.ac.uk
Title
Cited by
Cited by
Year
Detection of long repeat expansions from PCR-free whole-genome sequence data
E Dolzhenko, JJ Van Vugt, RJ Shaw, MA Bekritsky, M Van Blitterswijk, ...
Genome research 27 (11), 1895-1903, 2017
3212017
A multicentre validation study of the diagnostic value of plasma neurofilament light
NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ...
Nature communications 12 (1), 3400, 2021
2832021
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology
W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ...
Nature genetics 53 (12), 1636-1648, 2021
2812021
Stage at which riluzole treatment prolongs survival in patients with amyotrophic lateral sclerosis: a retrospective analysis of data from a dose-ranging study
T Fang, A Al Khleifat, JH Meurgey, A Jones, PN Leigh, G Bensimon, ...
The Lancet Neurology 17 (5), 416-422, 2018
2422018
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ...
Nature genetics 53 (9), 1311-1321, 2021
2322021
Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis
European Journal of Human Genetics 26 (10), 1537-1546, 2018
1322018
What causes amyotrophic lateral sclerosis?
S Martin, A Al Khleifat, A Al-Chalabi
F1000Research 6, 2017
1252017
Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein
SMK Farhan, DP Howrigan, LE Abbott, JR Klim, SD Topp, AE Byrnes, ...
Nature neuroscience 22 (12), 1966-1974, 2019
1122019
C9orf72 intermediate expansions of 24–30 repeats are associated with ALS
A Iacoangeli, A Al Khleifat, AR Jones, W Sproviero, A Shatunov, ...
Acta neuropathologica communications 7, 1-7, 2019
1012019
A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK
S Morgan, A Shatunov, W Sproviero, AR Jones, M Shoai, D Hughes, ...
Brain 140 (6), 1611-1618, 2017
972017
Safety and efficacy of nabiximols on spasticity symptoms in patients with motor neuron disease (CANALS): a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial
N Riva, G Mora, G Sorarù, C Lunetta, OE Ferraro, Y Falzone, L Leocani, ...
The Lancet Neurology 18 (2), 155-164, 2019
892019
Comparison of the King’s and MiToS staging systems for ALS
T Fang, A Al Khleifat, DR Stahl, C Lazo La Torre, C Murphy, ...
Amyotrophic lateral sclerosis and frontotemporal degeneration 18 (3-4), 227-232, 2017
862017
Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias
PR Mehta, AR Jones, S Opie-Martin, A Shatunov, A Iacoangeli, ...
Journal of Neurology, Neurosurgery & Psychiatry 90 (3), 268-271, 2019
612019
Association of variants in the SPTLC1 gene with juvenile amyotrophic lateral sclerosis
JO Johnson, R Chia, DE Miller, R Li, R Kumaran, Y Abramzon, ...
JAMA neurology 78 (10), 1236-1248, 2021
562021
Genome-wide meta-analysis finds the ACSL5-ZDHHC6 locus is associated with ALS and links weight loss to the disease genetics
A Iacoangeli, T Lin, A Al Khleifat, AR Jones, S Opie-Martin, JRI Coleman, ...
Cell Reports 33 (4), 2020
482020
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS
PJ Hop, RAJ Zwamborn, E Hannon, GL Shireby, MF Nabais, EM Walker, ...
Science translational medicine 14 (633), eabj0264, 2022
472022
A standard operating procedure for King’s ALS clinical staging
R Balendra, A Al Khleifat, T Fang, A Al-Chalabi
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 20 (3-4), 159-164, 2019
432019
Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis
A Al Khleifat, A Iacoangeli, JJFA Van Vugt, H Bowles, M Moisse, ...
NPJ genomic medicine 7 (1), 8, 2022
332022
Whole-genome sequencing reveals that variants in the interleukin 18 receptor accessory protein 3′ UTR protect against ALS
C Eitan, A Siany, E Barkan, T Olender, KR van Eijk, M Moisse, ...
Nature neuroscience 25 (4), 433-445, 2022
252022
The impact of age on genetic testing decisions in amyotrophic lateral sclerosis
PR Mehta, A Iacoangeli, S Opie-Martin, JJFA van Vugt, A Al Khleifat, ...
Brain 145 (12), 4440-4447, 2022
242022
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