A modified γ-retrovirus vector for X-linked severe combined immunodeficiency S Hacein-Bey-Abina, SY Pai, HB Gaspar, M Armant, CC Berry, S Blanche, ... New England Journal of Medicine 371 (15), 1407-1417, 2014 | 476 | 2014 |
Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor SK Selvaraj, RK Giri, N Perelman, C Johnson, P Malik, VK Kalra Blood 102 (4), 1515-1524, 2003 | 371 | 2003 |
Pulmonary macrophage transplantation therapy T Suzuki, P Arumugam, T Sakagami, N Lachmann, C Chalk, A Sallese, ... Nature 514 (7523), 450, 2014 | 325 | 2014 |
Successful correction of the human β-thalassemia major phenotype using a lentiviral vector G Puthenveetil, J Scholes, D Carbonell, N Qureshi, P Xia, L Zeng, S Li, ... Blood 104 (12), 3445-3453, 2004 | 269 | 2004 |
Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management SK Ballas, MR Kesen, MF Goldberg, GA Lutty, C Dampier, I Osunkwo, ... The Scientific World Journal 2012, 2012 | 256 | 2012 |
Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease A George, S Pushkaran, DG Konstantinidis, S Koochaki, P Malik, ... Blood 121 (11), 2099-2107, 2013 | 217 | 2013 |
Therapeutic strategies for sickle cell disease: towards a multi-agent approach MJ Telen, P Malik, GM Vercellotti Nature Reviews Drug Discovery 18 (2), 139-158, 2019 | 201 | 2019 |
Pediatric tumor cells express erythropoietin and a functional erythropoietin receptor that promotes angiogenesis and tumor cell survival S Batra, N Perelman, LR Luck, H Shimada, P Malik Laboratory investigation 83 (10), 1477, 2003 | 194 | 2003 |
Placenta growth factor activates monocytes and correlates with sickle cell disease severity N Perelman, SK Selvaraj, S Batra, LR Luck, A Erdreich-Epstein, ... Blood 102 (4), 1506-1514, 2003 | 189 | 2003 |
Ineffective erythropoiesis in β-thalassemia major is due to apoptosis at the polychromatophilic normoblast stage LA Mathias, TC Fisher, L Zeng, HJ Meiselman, KI Weinberg, AL Hiti, ... Experimental hematology 28 (12), 1343-1353, 2000 | 183 | 2000 |
CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites R Jayavaradhan, DM Pillis, M Goodman, F Zhang, Y Zhang, ... Nature communications 10 (1), 2866, 2019 | 163 | 2019 |
G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment X Chen, K Skutt-Kakaria, J Davison, YL Ou, E Choi, P Malik, K Loeb, ... Genes & development 26 (22), 2499-2511, 2012 | 161 | 2012 |
Improved human β-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element PI Arumugam, J Scholes, N Perelman, P Xia, JK Yee, P Malik Molecular Therapy 15 (10), 1863-1871, 2007 | 154 | 2007 |
Constitutive HOXA5 expression inhibits erythropoiesis and increases myelopoiesis from human hematopoietic progenitors GM Crooks, J Fuller, D Petersen, P Izadi, P Malik, PK Pattengale, ... Blood 94 (2), 519-528, 1999 | 152 | 1999 |
Cardiomyopathy with restrictive physiology in sickle cell disease O Niss, CT Quinn, A Lane, J Daily, PR Khoury, N Bakeer, TR Kimball, ... JACC: Cardiovascular Imaging 9 (3), 243-252, 2016 | 144 | 2016 |
High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors F Moreau-Gaudry, P Xia, G Jiang, NP Perelman, G Bauer, J Ellis, ... Blood 98 (9), 2664-2672, 2001 | 144 | 2001 |
Pathophysiology and therapy for haemoglobinopathies; Part I: sickle cell disease C Madigan, P Malik Expert reviews in molecular medicine 8 (9), 1-23, 2006 | 141 | 2006 |
Integrated genomic analysis of diverse induced pluripotent stem cells from the progenitor cell biology consortium N Salomonis, PJ Dexheimer, L Omberg, R Schroll, S Bush, J Huo, ... Stem cell reports 7 (1), 110-125, 2016 | 129 | 2016 |
The woodchuck hepatitis virus post-transcriptional regulatory element reduces readthrough transcription from retroviral vectors T Higashimoto, F Urbinati, A Perumbeti, G Jiang, A Zarzuela, LJ Chang, ... Gene therapy 14 (17), 1298, 2007 | 124 | 2007 |
An in vitro model of human red blood cell production from hematopoietic progenitor cells P Malik, TC Fisher, LLW Barsky, L Zeng, P Izadi, AL Hiti, KI Weinberg, ... Blood 91 (8), 2664-2671, 1998 | 124 | 1998 |