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Paul Bastard
Paul Bastard
Imagine Institute, Paris, France
Verified email at institutimagine.org
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Cited by
Cited by
Year
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ...
Science 370 (6515), eabd4585, 2020
24502020
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ...
Science 370 (6515), eabd4570, 2020
21252020
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
4402021
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19
T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ...
Science immunology 6 (62), eabl4348, 2021
3252021
Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity
Y Guo, M Audry, M Ciancanelli, L Alsina, J Azevedo, M Herman, ...
Journal of Experimental Medicine 208 (10), 2083-2098, 2011
3152011
A global effort to define the human genetics of protective immunity to SARS-CoV-2 infection
JL Casanova, HC Su, L Abel, A Aiuti, S Almuhsen, AA Arias, P Bastard, ...
Cell 181 (6), 1194-1199, 2020
2522020
Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1
P Bastard, E Orlova, L Sozaeva, R Lévy, A James, MM Schmitt, S Ochoa, ...
Journal of Experimental Medicine 218 (7), 2021
2292021
Human genetic and immunological determinants of critical COVID-19 pneumonia
Q Zhang, P Bastard, A Cobat, JL Casanova
Nature 603 (7902), 587-598, 2022
2192022
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19
MGP van der Wijst, SE Vazquez, GC Hartoularos, P Bastard, T Grant, ...
Science translational medicine 13 (612), eabh2624, 2021
1712021
Severe influenza pneumonitis in children with inherited TLR3 deficiency
HK Lim, SXL Huang, J Chen, G Kerner, O Gilliaux, P Bastard, K Dobbs, ...
Journal of Experimental Medicine 216 (9), 2038-2056, 2019
1552019
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine
P Bastard, E Michailidis, HH Hoffmann, M Chbihi, T Le Voyer, J Rosain, ...
Journal of Experimental Medicine 218 (4), e20202486, 2021
1432021
Life-threatening COVID-19: defective interferons unleash excessive inflammation
Q Zhang, P Bastard, A Bolze, E Jouanguy, SY Zhang, A Cobat, ...
Med 1 (1), 14-20, 2020
1402020
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ...
Proceedings of the National Academy of Sciences 119 (21), 2022
1282022
Polyclonal expansion of TCR Vβ 21.3+ CD4+ and CD8+ T cells is a hallmark of multisystem inflammatory syndrome in children
M Moreews, K Le Gouge, S Khaldi-Plassart, R Pescarmona, AL Mathieu, ...
Science immunology 6 (59), eabh1516, 2021
1262021
Early nasal type I IFN immunity against SARS-CoV-2 is compromised in patients with autoantibodies against type I IFNs
J Lopez, M Mommert, W Mouton, A Pizzorno, K Brengel-Pesce, M Mezidi, ...
Journal of Experimental Medicine 218 (10), e20211211, 2021
1202021
Artificial intelligence in nephrology: core concepts, clinical applications, and perspectives
O Niel, P Bastard
American Journal of Kidney Diseases 74 (6), 803-810, 2019
1182019
Neutralizing autoantibodies to type I IFNs in> 10% of patients with severe COVID-19 pneumonia hospitalized in Madrid, Spain
J Troya, P Bastard, L Planas-Serra, P Ryan, M Ruiz, M de Carranza, ...
Journal of clinical immunology 41, 914-922, 2021
1162021
Autoantibodies against type I interferons are associated with multi-organ failure in COVID-19 patients
R Koning, P Bastard, JL Casanova, MC Brouwer, D van de Beek
Intensive care medicine 47, 704-706, 2021
1092021
Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies
J Damoiseaux, A Dotan, MJ Fritzler, DP Bogdanos, PL Meroni, ...
Autoimmunity Reviews 21 (3), 103012, 2022
902022
COVID Human Genetic Effort, Cobat A, Casanova JL
Q Zhang, P Bastard
Human genetic and immunological determinants of critical COVID-19 pneumonia …, 2022
902022
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