Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-I in cultured bovine articular cartilage DJ McQUILLAN, CJ Handley, MA Campbell, S Bolis, VE Milway, ... Biochemical Journal 240 (2), 423-430, 1986 | 378 | 1986 |
Variants within the COL5A1 gene are associated with Achilles tendinopathy in two populations AV September, J Cook, CJ Handley, L van der Merwe, MP Schwellnus, ... British journal of sports medicine 43 (5), 357-365, 2009 | 259 | 2009 |
The effect of serum on biosynthesis of proteoglycans by bovine articular cartilage in culture VC Hascall, CJ Handley, DJ McQuillan, GK Hascall, HC Robinson, ... Archives of Biochemistry and Biophysics 224 (1), 206-223, 1983 | 223 | 1983 |
Mechanism of catabolism of aggrecan by articular cartilage MZ Ilic, CJ Handley, HC Robinson, MT Mok Archives of biochemistry and biophysics 294 (1), 115-122, 1992 | 209 | 1992 |
In vitro response of chondrocytes to mechanical loading. The effect of short term mechanical tension MT De Witt, CJ Handley, BW Oakes, DA Lowther Connective tissue research 12 (2), 97-109, 1984 | 207 | 1984 |
Changes in the composition of the extracellular matrix in patellar tendinopathy S Tom, J Parkinson, MZ Ilic, J Cook, JA Feller, CJ Handley Matrix Biology 28 (4), 230-236, 2009 | 191 | 2009 |
Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin b and an inhibitor of matrix metalloproteinases. evidence for two converging pathways of … DJ Buttle, CJ Handley, MZ Ilic, J Saklatvala, M Murata, AJ Barrett Arthritis & Rheumatism 36 (12), 1709-1717, 1993 | 146 | 1993 |
Expression and activity of ADAMTS‐5 in synovium MN Vankemmelbeke, I Holen, AG Wilson, MZ Ilic, CJ Handley, GS Kelner, ... European Journal of Biochemistry 268 (5), 1259-1268, 2001 | 145 | 2001 |
The synthesis of elastin, collagen, and glycosaminoglycans by high density primary cultures of neonatal rat aortic smooth muscle. An ultrastructural and biochemical study. BW Oakes, AC Batty, CJ Handley, LB Sandberg European journal of cell biology 27 (1), 34-46, 1982 | 144 | 1982 |
Selective inhibition of ADAMTS‐1,‐4 and‐5 by catechin gallate esters MN Vankemmelbeke, GC Jones, C Fowles, MZ Ilic, CJ Handley, AJ Day, ... European journal of biochemistry 270 (11), 2394-2403, 2003 | 136 | 2003 |
Characterisation of proteoglycans and their catabolic products in tendon and explant cultures of tendon T Samiric, MZ Ilic, CJ Handley Matrix biology 23 (2), 127-140, 2004 | 133 | 2004 |
Inhibition of proteoglycan biosynthesis by hyaluronic acid in chondrocytes in cell culture CJ Handley, DA Lowther Biochimica et Biophysica Acta (BBA)-General Subjects 444 (1), 69-74, 1976 | 127 | 1976 |
Components of the transforming growth factor-β family and the pathogenesis of human Achilles tendon pathology—a genetic association study M Posthumus, M Collins, J Cook, CJ Handley, WJ Ribbans, RKW Smith, ... Rheumatology 49 (11), 2090-2097, 2010 | 121 | 2010 |
Turnover of proteoglycans in cultures of bovine articular cartilage MA Campbell, CJ Handley, VC Hascall, RA Campbell, DA Lowther Archives of biochemistry and biophysics 234 (1), 275-289, 1984 | 113 | 1984 |
Oxygen free-radicals mediate an inhibition of proteoglycan synthesis in cultured articular cartilage. EJ Bates, DA Lowther, CJ Handley Annals of the rheumatic diseases 43 (3), 462-469, 1984 | 104 | 1984 |
Involvement of proteoglycans in tendinopathy J Parkinson, T Samiric, MZ Ilic, J Cook, CJ Handley The Journal of Musculoskeletal and Neuronal Interactions 11 (2), 86-93, 2011 | 102 | 2011 |
Change in proteoglycan metabolism is a characteristic of human patellar tendinopathy J Parkinson, T Samiric, MZ Ilic, J Cook, JA Feller, CJ Handley Arthritis & Rheumatism 62 (10), 3028-3035, 2010 | 94 | 2010 |
The apoptosis pathway and the genetic predisposition to Achilles tendinopathy EM Nell, L Van Der Merwe, J Cook, CJ Handley, M Collins, AV September Journal of Orthopaedic Research 30 (11), 1719-1724, 2012 | 91 | 2012 |
The oxidant hypochlorite (OCl−), a product of the myeloperoxidase system, degrades articular cartilage proteoglycan aggregate M Katrantzis, MS Baker, CJ Handley, DA Lowther Free Radical Biology and Medicine 10 (2), 101-109, 1991 | 78 | 1991 |
Polymorphic variation within the ADAMTS2, ADAMTS14, ADAMTS5, ADAM12 and TIMP2 genes and the risk of Achilles tendon pathology: a genetic association study L El Khoury, M Posthumus, M Collins, CJ Handley, J Cook, SM Raleigh Journal of science and medicine in sport 16 (6), 493-498, 2013 | 77 | 2013 |