| A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP. 664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies RW Sanders, R Derking, A Cupo, JP Julien, A Yasmeen, N de Val, HJ Kim, ... PLoS pathogens 9 (9), e1003618, 2013 | 1022 | 2013 |
| Crystal structure of a soluble cleaved HIV-1 envelope trimer JP Julien, A Cupo, D Sok, RL Stanfield, D Lyumkis, MC Deller, PJ Klasse, ... Science 342 (6165), 1477-1483, 2013 | 976 | 2013 |
| Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer D Lyumkis, JP Julien, N De Val, A Cupo, CS Potter, PJ Klasse, DR Burton, ... Science 342 (6165), 1484-1490, 2013 | 808 | 2013 |
| Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120 RS Veazey, RJ Shattock, M Pope, JC Kirijan, J Jones, Q Hu, T Ketas, ... Nature medicine 9 (3), 343-346, 2003 | 580 | 2003 |
| HIV-1 neutralizing antibodies induced by native-like envelope trimers RW Sanders, MJ van Gils, R Derking, D Sok, TJ Ketas, JA Burger, ... Science 349 (6244), aac4223, 2015 | 558 | 2015 |
| Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface J Huang, BH Kang, M Pancera, JH Lee, T Tong, Y Feng, H Imamichi, ... Nature 515 (7525), 138-142, 2014 | 520 | 2014 |
| Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4 N Signoret, J Oldridge, A Pelchen-Matthews, PJ Klasse, T Tran, LF Brass, ... The Journal of cell biology 139 (3), 651-664, 1997 | 487 | 1997 |
| Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 L Kong, JH Lee, KJ Doores, CD Murin, JP Julien, R McBride, Y Liu, ... Nature structural & molecular biology 20 (7), 796-803, 2013 | 418 | 2013 |
| V3: HIV's switch-hitter O Hartley, PJ Klasse, QJ Sattentau, JP Moore AIDS Research & Human Retroviruses 21 (2), 171-189, 2005 | 411 | 2005 |
| Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus–cell fusion RS Veazey, PJ Klasse, SM Schader, Q Hu, TJ Ketas, M Lu, PA Marx, ... Nature 438 (7064), 99-102, 2005 | 399 | 2005 |
| Occupancy and mechanism in antibody-mediated neutralization of animal viruses PJ Klasse, QJ Sattentau Journal of General Virology 83 (9), 2091-2108, 2002 | 385 | 2002 |
| Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes SW De Taeye, G Ozorowski, AT de la Peņa, M Guttman, JP Julien, ... Cell 163 (7), 1702-1715, 2015 | 355 | 2015 |
| Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers WS Horne, LM Johnson, TJ Ketas, PJ Klasse, M Lu, JP Moore, ... Proceedings of the National Academy of Sciences 106 (35), 14751-14756, 2009 | 322 | 2009 |
| Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9 JP Julien, JH Lee, A Cupo, CD Murin, R Derking, S Hoffenberg, ... Proceedings of the National Academy of Sciences 110 (11), 4351-4356, 2013 | 312 | 2013 |
| Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody DR Burton, AJ Hessell, BF Keele, PJ Klasse, TA Ketas, B Moldt, ... Proceedings of the National Academy of Sciences 108 (27), 11181-11186, 2011 | 292 | 2011 |
| HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors B He, X Qiao, PJ Klasse, A Chiu, A Chadburn, DM Knowles, JP Moore, ... The Journal of Immunology 176 (7), 3931-3941, 2006 | 288 | 2006 |
| Neutralization of virus infectivity by antibodies: old problems in new perspectives PJ Klasse Advances in biology 2014 (1), 157895, 2014 | 278 | 2014 |
| A Native-Like SOSIP.664 Trimer Based on an HIV-1 Subtype B env Gene P Pugach, G Ozorowski, A Cupo, R Ringe, A Yasmeen, N de Val, ... Journal of virology 89 (6), 3380-3395, 2015 | 277 | 2015 |
| Composition and antigenic effects of individual glycan sites of a trimeric HIV-1 envelope glycoprotein AJ Behrens, S Vasiljevic, LK Pritchard, DJ Harvey, RS Andev, SA Krumm, ... Cell reports 14 (11), 2695-2706, 2016 | 276 | 2016 |
| A broadly neutralizing antibody targets the dynamic HIV envelope trimer apex via a long, rigidified, and anionic β-hairpin structure JH Lee, R Andrabi, CY Su, A Yasmeen, JP Julien, L Kong, NC Wu, ... Immunity 46 (4), 690-702, 2017 | 249 | 2017 |
Jean-Philippe JulienScientist, Hospital for Sick Children Research InstituteVerified email at sickkids.ca
