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Alan Engelman
Alan Engelman
Dana-Farber Cancer Institute
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
Identification of host proteins required for HIV infection through a functional genomic screen
AL Brass, DM Dykxhoorn, Y Benita, N Yan, A Engelman, RJ Xavier, ...
science 319 (5865), 921-926, 2008
17832008
Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases
F Dyda, AB Hickman, TM Jenkins, A Engelman, R Craigie, DR Davies
Science 266 (5193), 1981-1986, 1994
10531994
HIV-1 DNA integration: mechanism of viral DNA cleavage and DNA strand transfer
A Engelman, K Mizuuchi, R Craigie
Cell 67 (6), 1211-1221, 1991
8941991
Retroviral intasome assembly and inhibition of DNA strand transfer
S Hare, SS Gupta, E Valkov, A Engelman, P Cherepanov
Nature 464 (7286), 232-236, 2010
7892010
The structural biology of HIV-1: mechanistic and therapeutic insights
A Engelman, P Cherepanov
Nature Reviews Microbiology 10 (4), 279-290, 2012
7222012
Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro
A Engelman, R Craigie
Journal of virology 66 (11), 6361-6369, 1992
6731992
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
MC Shun, NK Raghavendra, N Vandegraaff, JE Daigle, S Hughes, ...
Genes & development 21 (14), 1767-1778, 2007
5762007
Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication
A Engelman, G Englund, JM Orenstein, MA Martin, R Craigie
Journal of virology 69 (5), 2729-2736, 1995
5431995
Flexible use of nuclear import pathways by HIV-1
KE Lee, Z Ambrose, TD Martin, I Oztop, A Mulky, JG Julias, N Vandegraaff, ...
Cell host & microbe 7 (3), 221-233, 2010
5322010
Haematopoietic stem and progenitor cells from human pluripotent stem cells
R Sugimura, DK Jha, A Han, C Soria-Valles, EL Da Rocha, YF Lu, ...
Nature 545 (7655), 432-438, 2017
4962017
Structural basis for the recognition between HIV-1 integrase and transcriptional coactivator p75
P Cherepanov, ALB Ambrosio, S Rahman, T Ellenberger, A Engelman
Proceedings of the National Academy of Sciences 102 (48), 17308-17313, 2005
4792005
Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding.
FD Bushman, A Engelman, I Palmer, P Wingfield, R Craigie
Proceedings of the National Academy of Sciences 90 (8), 3428-3432, 1993
4681993
Identification of discrete functional domains of HIV‐1 integrase and their organization within an active multimeric complex.
A Engelman, FD Bushman, R Craigie
The EMBO journal 12 (8), 3269-3275, 1993
4531993
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
JK Nuņez, ASY Lee, A Engelman, JA Doudna
Nature 519 (7542), 193-198, 2015
4282015
Solution structure of the DNA binding domain of HIV-1 integrase
PJ Lodi, JA Ernst, J Kuszewski, AB Hickman, A Engelman, R Craigie, ...
Biochemistry 34 (31), 9826-9833, 1995
3971995
A Soluble Active Mutant of HIV-1 Integrase: INVOLVEMENT OF BOTH THE CORE AND CARBOXYL-TERMINAL DOMAINS IN MULTIMERIZATION (∗)
TM Jenkins, A Engelman, R Ghirlando, R Craigie
Journal of Biological Chemistry 271 (13), 7712-7718, 1996
3751996
Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration
JL Mbisa, R Barr, JA Thomas, N Vandegraaff, IJ Dorweiler, ...
Journal of virology 81 (13), 7099-7110, 2007
3392007
Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase
P Cherepanov, E Devroe, PA Silver, A Engelman
Journal of Biological Chemistry 279 (47), 48883-48892, 2004
3302004
The lentiviral integrase binding protein LEDGF/p75 and HIV-1 replication
A Engelman, P Cherepanov
PLoS pathogens 4 (3), e1000046, 2008
3072008
Critical contacts between HIV‐1 integrase and viral DNA identified by structure‐based analysis and photo‐crosslinking
TM Jenkins, D Esposito, A Engelman, R Craigie
The EMBO Journal, 1997
3021997
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