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Francesco R Simonetti
Francesco R Simonetti
Verified email at jhmi.edu
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Year
Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
F Maldarelli, X Wu, L Su, FR Simonetti, W Shao, S Hill, J Spindler, ...
Science 345 (6193), 179-183, 2014
9052014
A quantitative approach for measuring the reservoir of latent HIV-1 proviruses
KM Bruner, Z Wang, FR Simonetti, AM Bender, KJ Kwon, S Sengupta, ...
Nature 566 (7742), 120-125, 2019
5732019
Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo
FR Simonetti, MD Sobolewski, E Fyne, W Shao, J Spindler, J Hattori, ...
Proceedings of the National Academy of Sciences 113 (7), 1883-1888, 2016
3842016
Antigen-driven clonal selection shapes the persistence of HIV-1–infected CD4+ T cells in vivo
FR Simonetti, H Zhang, GP Soroosh, J Duan, K Rhodehouse, AL Hill, ...
The Journal of clinical investigation 131 (3), 2021
1292021
Different human resting memory CD4+ T cell subsets show similar low inducibility of latent HIV-1 proviruses
KJ Kwon, AE Timmons, S Sengupta, FR Simonetti, H Zhang, R Hoh, ...
Science translational medicine 12 (528), eaax6795, 2020
902020
Intact proviral DNA assay analysis of large cohorts of people with HIV provides a benchmark for the frequency and composition of persistent proviral DNA
FR Simonetti, JA White, C Tumiotto, KD Ritter, M Cai, RT Gandhi, ...
Proceedings of the National Academy of Sciences 117 (31), 18692-18700, 2020
892020
Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir
Z Wang, FR Simonetti, RF Siliciano, GM Laird
Retrovirology 15, 1-9, 2018
862018
The landscape of persistent viral genomes in ART-treated SIV, SHIV, and HIV-2 infections
AM Bender, FR Simonetti, MR Kumar, EJ Fray, KM Bruner, AE Timmons, ...
Cell host & microbe 26 (1), 73-85. e4, 2019
842019
No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication
G Bozzi, FR Simonetti, SA Watters, EM Anderson, M Gouzoulis, ...
Science advances 5 (9), eaav2045, 2019
792019
The forces driving clonal expansion of the HIV-1 latent reservoir
R Liu, FR Simonetti, YC Ho
Virology journal 17 (1), 4, 2020
782020
Clones of infected cells arise early in HIV-infected individuals
JM Coffin, DW Wells, JM Zerbato, JD Kuruc, S Guo, BT Luke, JJ Eron, ...
JCI insight 4 (12), 2019
782019
The role of CD32 during HIV-1 infection
LN Bertagnolli, JA White, FR Simonetti, SA Beg, J Lai, C Tomescu, ...
Nature 561 (7723), E17-E19, 2018
622018
HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus
A Musick, J Spindler, E Boritz, L Pérez, D Crespo-Vélez, SC Patro, ...
Frontiers in microbiology 10, 2204, 2019
612019
Complex decay dynamics of HIV virions, intact and defective proviruses, and 2LTR circles following initiation of antiretroviral therapy
JA White, FR Simonetti, S Beg, NF McMyn, W Dai, N Bachmann, J Lai, ...
Proceedings of the National Academy of Sciences 119 (6), e2120326119, 2022
532022
Autologous IgG antibodies block outgrowth of a substantial but variable fraction of viruses in the latent reservoir for HIV-1
LN Bertagnolli, J Varriale, S Sweet, J Brockhurst, FR Simonetti, J White, ...
Proceedings of the National Academy of Sciences 117 (50), 32066-32077, 2020
522020
Origin, evolution, and phylogeography of recent epidemic CHIKV strains
AL Presti, M Ciccozzi, E Cella, A Lai, FR Simonetti, M Galli, G Zehender, ...
Infection, Genetics and Evolution 12 (2), 392-398, 2012
522012
Clonally expanded HIV-1 proviruses with 5-leader defects can give rise to nonsuppressible residual viremia
JA White, F Wu, S Yasin, M Moskovljevic, J Varriale, F Dragoni, ...
The Journal of clinical investigation 133 (6), 2023
402023
Dynamic shifts in the HIV proviral landscape during long term combination antiretroviral therapy: implications for persistence and control of HIV infections
EM Anderson, FR Simonetti, RJ Gorelick, S Hill, MA Gouzoulis, J Bell, ...
Viruses 12 (2), 136, 2020
392020
influence of ART on HIV genetics
FR Simonetti, MF Kearney
Current Opinion in HIV and AIDS 10 (1), 49-54, 2015
342015
Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods
JA White, JT Kufera, N Bachmann, W Dai, FR Simonetti, C Armstrong, ...
PLoS pathogens 18 (9), e1010845, 2022
332022
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