Shixin Liu
Shixin Liu
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Optical tweezers in single-molecule biophysics
CJ Bustamante, YR Chemla, S Liu, MD Wang
Nature Reviews Methods Primers 1 (1), 25, 2021
Slide into action: dynamic shuttling of HIV reverse transcriptase on nucleic acid substrates
S Liu, EA Abbondanzieri, JW Rausch, SFJL Grice, X Zhuang
Science 322 (5904), 1092-1097, 2008
Reversible histone glycation is associated with disease-related changes in chromatin architecture
Q Zheng, ND Omans, R Leicher, A Osunsade, AS Agustinus, ...
Nature Communications 10 (1), 1289, 2019
A viral packaging motor varies its DNA rotation and step size to preserve subunit coordination as the capsid fills
S Liu, G Chistol, CL Hetherington, S Tafoya, K Aathavan, J Schnitzbauer, ...
Cell 157 (3), 702-713, 2014
Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism
M Dangkulwanich, T Ishibashi, S Liu, ML Kireeva, L Lubkowska, ...
Elife 2, e00971, 2013
High degree of coordination and division of labor among subunits in a homomeric ring ATPase
G Chistol, S Liu, CL Hetherington, JR Moffitt, S Grimes, PJ Jardine, ...
Cell 151 (5), 1017-1028, 2012
Replication fork activation is enabled by a single-stranded DNA gate in CMG helicase
MR Wasserman, GD Schauer, ME O’Donnell, S Liu
Cell 178 (3), 600-611. e16, 2019
Dissecting the multistep reaction pathway of an RNA enzyme by single-molecule kinetic “fingerprinting”
S Liu, G Bokinsky, NG Walter, X Zhuang
Proceedings of the National Academy of Sciences 104 (31), 12634-12639, 2007
Full-length RNA profiling reveals pervasive bidirectional transcription terminators in bacteria
X Ju, D Li, S Liu
Nature microbiology 4 (11), 1907-1918, 2019
Initiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription
S Liu, BT Harada, JT Miller, SFJ Le Grice, X Zhuang
Nature structural & molecular biology 17 (12), 1453-1460, 2010
Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses
L Wang, ZL Johnson, MR Wasserman, J Levring, J Chen, S Liu
Elife 9, e56451, 2020
A single amino acid change (Asp 53→ Ala53) converts Survivin from anti-apoptotic to pro-apoptotic
Z Song, S Liu, H He, N Hoti, Y Wang, S Feng, M Wu
Molecular biology of the cell 15 (3), 1287-1296, 2004
Molecular mechanism for direct actin force-sensing by α-catenin
L Mei, S Espinosa de los Reyes, MJ Reynolds, R Leicher, S Liu, ...
Elife 9, e62514, 2020
Two distinct binding modes of a protein cofactor with its target RNA
G Bokinsky, LG Nivón, S Liu, G Chai, M Hong, KM Weeks, X Zhuang
Journal of molecular biology 361 (4), 771-784, 2006
Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H
S Chung, M Wendeler, JW Rausch, G Beilhartz, M Gotte, BR O'Keefe, ...
Antimicrobial agents and chemotherapy 54 (9), 3913-3921, 2010
Nonreciprocal and conditional cooperativity directs the pioneer activity of pluripotency transcription factors
S Li, EB Zheng, L Zhao, S Liu
Cell Reports 28 (10), 2689-2703. e4, 2019
Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase
KJ Mickolajczyk, PMM Shelton, M Grasso, X Cao, SE Warrington, A Aher, ...
Biophysical journal 120 (6), 1020-1030, 2021
Dynamics of Cas10 govern discrimination between self and non-self in type III CRISPR-Cas immunity
L Wang, CY Mo, MR Wasserman, JT Rostøl, LA Marraffini, S Liu
Molecular cell 73 (2), 278-290. e4, 2019
Mechanical operation and intersubunit coordination of ring-shaped molecular motors: insights from single-molecule studies
S Liu, G Chistol, C Bustamante
Biophysical journal 106 (9), 1844-1858, 2014
Using a system’s equilibrium behavior to reduce its energy dissipation in nonequilibrium processes
S Tafoya, SJ Large, S Liu, C Bustamante, DA Sivak
Proceedings of the National Academy of Sciences 116 (13), 5920-5924, 2019
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