| Optical tweezers in single-molecule biophysics CJ Bustamante, YR Chemla, S Liu, MD Wang Nature Reviews Methods Primers 1 (1), 25, 2021 | 468 | 2021 |
| Slide into action: dynamic shuttling of HIV reverse transcriptase on nucleic acid substrates S Liu, EA Abbondanzieri, JW Rausch, SFJL Grice, X Zhuang Science 322 (5904), 1092-1097, 2008 | 205 | 2008 |
| Reversible histone glycation is associated with disease-related changes in chromatin architecture Q Zheng, ND Omans, R Leicher, A Osunsade, AS Agustinus, ... Nature Communications 10 (1), 1289, 2019 | 166 | 2019 |
| A viral packaging motor varies its DNA rotation and step size to preserve subunit coordination as the capsid fills S Liu, G Chistol, CL Hetherington, S Tafoya, K Aathavan, J Schnitzbauer, ... Cell 157 (3), 702-713, 2014 | 149 | 2014 |
| Complete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanism M Dangkulwanich, T Ishibashi, S Liu, ML Kireeva, L Lubkowska, ... Elife 2, e00971, 2013 | 147 | 2013 |
| Replication fork activation is enabled by a single-stranded DNA gate in CMG helicase MR Wasserman, GD Schauer, ME O’Donnell, S Liu Cell 178 (3), 600-611. e16, 2019 | 132 | 2019 |
| High degree of coordination and division of labor among subunits in a homomeric ring ATPase G Chistol, S Liu, CL Hetherington, JR Moffitt, S Grimes, PJ Jardine, ... Cell 151 (5), 1017-1028, 2012 | 131 | 2012 |
| Dissecting the multistep reaction pathway of an RNA enzyme by single-molecule kinetic “fingerprinting” S Liu, G Bokinsky, NG Walter, X Zhuang Proceedings of the National Academy of Sciences 104 (31), 12634-12639, 2007 | 109 | 2007 |
| Full-length RNA profiling reveals pervasive bidirectional transcription terminators in bacteria X Ju, D Li, S Liu Nature microbiology 4 (11), 1907-1918, 2019 | 102 | 2019 |
| Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses L Wang, ZL Johnson, MR Wasserman, J Levring, J Chen, S Liu Elife 9, e56451, 2020 | 86 | 2020 |
| Initiation complex dynamics direct the transitions between distinct phases of early HIV reverse transcription S Liu, BT Harada, JT Miller, SFJ Le Grice, X Zhuang Nature structural & molecular biology 17 (12), 1453-1460, 2010 | 85 | 2010 |
| Molecular mechanism for direct actin force-sensing by α-catenin L Mei, S Espinosa de los Reyes, MJ Reynolds, R Leicher, S Liu, ... Elife 9, e62514, 2020 | 76 | 2020 |
| A single amino acid change (Asp 53→ Ala53) converts Survivin from anti-apoptotic to pro-apoptotic Z Song, S Liu, H He, N Hoti, Y Wang, S Feng, M Wu Molecular biology of the cell 15 (3), 1287-1296, 2004 | 74 | 2004 |
| Two distinct binding modes of a protein cofactor with its target RNA G Bokinsky, LG Nivón, S Liu, G Chai, M Hong, KM Weeks, X Zhuang Journal of molecular biology 361 (4), 771-784, 2006 | 71 | 2006 |
| Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H S Chung, M Wendeler, JW Rausch, G Beilhartz, M Gotte, BR O'Keefe, ... Antimicrobial agents and chemotherapy 54 (9), 3913-3921, 2010 | 62 | 2010 |
| Nonreciprocal and conditional cooperativity directs the pioneer activity of pluripotency transcription factors S Li, EB Zheng, L Zhao, S Liu Cell Reports 28 (10), 2689-2703. e4, 2019 | 59 | 2019 |
| Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase KJ Mickolajczyk, PMM Shelton, M Grasso, X Cao, SE Warrington, A Aher, ... Biophysical journal 120 (6), 1020-1030, 2021 | 53 | 2021 |
| Dynamics of Cas10 govern discrimination between self and non-self in type III CRISPR-Cas immunity L Wang, CY Mo, MR Wasserman, JT Rostøl, LA Marraffini, S Liu Molecular cell 73 (2), 278-290. e4, 2019 | 53 | 2019 |
| Mechanical operation and intersubunit coordination of ring-shaped molecular motors: insights from single-molecule studies S Liu, G Chistol, C Bustamante Biophysical journal 106 (9), 1844-1858, 2014 | 52 | 2014 |
| Using a system’s equilibrium behavior to reduce its energy dissipation in nonequilibrium processes S Tafoya, SJ Large, S Liu, C Bustamante, DA Sivak Proceedings of the National Academy of Sciences 116 (13), 5920-5924, 2019 | 50 | 2019 |
